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The map label for this gene is walR [H]

Identifier: 239617104

GI number: 239617104

Start: 759795

End: 760475

Strand: Reverse

Name: walR [H]

Synonym: Kole_0706

Alternate gene names: 239617104

Gene position: 760475-759795 (Counterclockwise)

Preceding gene: 239617105

Following gene: 239617103

Centisome position: 33.03

GC content: 42.0

Gene sequence:

>681_bases
GTGAAAATATTAGTGGTAGATGACGATCCGGATATCCTGAACATAGTGAAAACTGCTTGCGAACAGGAATGTTTTAATGT
TAGAACCGCAAATTCTGCCCGGAACATGTGGGAAGCATTGGAAAATGACCCACCGGATTTAATCGTGCTGGACATAATGC
TTCCCGATGCCAGTGGATTGGATGTCATAAAAAAACTTAAAAGAAAATACGAAGAGATACCGGTGATATTTCTTACGGCC
AGAAAATCCGATCTTGATATGATCCTTGGCCTTGAACTTGGTGCTGATGACTATATTACCAAGCCCTTTAATCCAAGAAC
CCTTATCGCCAGAATTAAAGCGGTGAGCAGGCGTTACGAAATGGGTCCAAAGGACAGAAACGTTGTGAAATTGGGTGACA
TTGAAATAGATATGAATTCATACAGCATGATAAAGGATGGGAAAAAAGAGGAACTTCCCAGAAAGGAATTTGAGCTTTTG
AAACTCATGATAGAGAACCCCGGAAAAGTCTTTAACCGCCAGGAAATCCTCGATAGGGTCTGGGGGATGGACTTCTTTGG
AGACTTTAGAACCGTTGATGTTCATATAAGCAAACTCAGAGAGAAAATCGGGAGCGAATTCATAAAAACTGTGCGAGGAG
TTGGGTACAAACTCGTTATCCCGGAGGATGAGAAGAGTTGA

Upstream 100 bases:

>100_bases
TTACCAGGTTTCTCGAAAGGGCTGCTGATCATATTACAAATATCTGCGAAGAAGTATATTTCATAGTTGAGGGAAAAAAC
CTGAAGGAGGAAATGCGCCG

Downstream 100 bases:

>100_bases
ACCGTGATTTTAAAACGATATTCGACAGCCTTTCTGATGGCATATTAGAGGTTGATGAAACTCTGCGGATTATTGATTGT
AACCGTGTTGCAGAGGGATT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILVVDDDPDILNIVKTACEQECFNVRTANSARNMWEALENDPPDLIVLDIMLPDASGLDVIKKLKRKYEEIPVIFLTA
RKSDLDMILGLELGADDYITKPFNPRTLIARIKAVSRRYEMGPKDRNVVKLGDIEIDMNSYSMIKDGKKEELPRKEFELL
KLMIENPGKVFNRQEILDRVWGMDFFGDFRTVDVHISKLREKIGSEFIKTVRGVGYKLVIPEDEKS

Sequences:

>Translated_226_residues
MKILVVDDDPDILNIVKTACEQECFNVRTANSARNMWEALENDPPDLIVLDIMLPDASGLDVIKKLKRKYEEIPVIFLTA
RKSDLDMILGLELGADDYITKPFNPRTLIARIKAVSRRYEMGPKDRNVVKLGDIEIDMNSYSMIKDGKKEELPRKEFELL
KLMIENPGKVFNRQEILDRVWGMDFFGDFRTVDVHISKLREKIGSEFIKTVRGVGYKLVIPEDEKS
>Mature_226_residues
MKILVVDDDPDILNIVKTACEQECFNVRTANSARNMWEALENDPPDLIVLDIMLPDASGLDVIKKLKRKYEEIPVIFLTA
RKSDLDMILGLELGADDYITKPFNPRTLIARIKAVSRRYEMGPKDRNVVKLGDIEIDMNSYSMIKDGKKEELPRKEFELL
KLMIENPGKVFNRQEILDRVWGMDFFGDFRTVDVHISKLREKIGSEFIKTVRGVGYKLVIPEDEKS

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.1785714285714, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=33.6170212765957, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.6491228070175, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=38.2608695652174, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.4260089686099, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=35.7798165137615, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=34.6666666666667, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=39.3013100436681, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.2678571428571, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=32.2869955156951, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.4444444444444, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=29.5454545454545, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.6943231441048, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790299, Length=127, Percent_Identity=32.2834645669291, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=30.0970873786408, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=31.6666666666667, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26036; Mature: 26036

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVVDDDPDILNIVKTACEQECFNVRTANSARNMWEALENDPPDLIVLDIMLPDASGL
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCH
DVIKKLKRKYEEIPVIFLTARKSDLDMILGLELGADDYITKPFNPRTLIARIKAVSRRYE
HHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
MGPKDRNVVKLGDIEIDMNSYSMIKDGKKEELPRKEFELLKLMIENPGKVFNRQEILDRV
CCCCCCCEEEECCEEECCCCHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
WGMDFFGDFRTVDVHISKLREKIGSEFIKTVRGVGYKLVIPEDEKS
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MKILVVDDDPDILNIVKTACEQECFNVRTANSARNMWEALENDPPDLIVLDIMLPDASGL
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCH
DVIKKLKRKYEEIPVIFLTARKSDLDMILGLELGADDYITKPFNPRTLIARIKAVSRRYE
HHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
MGPKDRNVVKLGDIEIDMNSYSMIKDGKKEELPRKEFELLKLMIENPGKVFNRQEILDRV
CCCCCCCEEEECCEEECCCCHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
WGMDFFGDFRTVDVHISKLREKIGSEFIKTVRGVGYKLVIPEDEKS
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA