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The map label for this gene is rbsK [H]

Identifier: 239617001

GI number: 239617001

Start: 648449

End: 649351

Strand: Reverse

Name: rbsK [H]

Synonym: Kole_0601

Alternate gene names: 239617001

Gene position: 649351-648449 (Counterclockwise)

Preceding gene: 239617002

Following gene: 239617000

Centisome position: 28.21

GC content: 44.3

Gene sequence:

>903_bases
ATGATAGCAGTAGTCGGAAGCAACAATGTTGATGTAGTTCTCACGGTTGACCATTTCACGCGCGCTGGTGAAACTCAAAA
GTGCACAACACTAAATTACTTTCCTGGTGGAAAAGGAGCCAATCAAGCAGTAGCTGCTAAAAAGTTAGGAGCAGAGGTTT
ATTTCCTGACATGTGTAGGCAATGATGGAAATGCGCAGTTTGCCGTTGAAAGCCTGAAAAAAGCTGGCTTAGAGAAAGGG
ATTAAAAAAGTTGATTCTCCCAATGGCATGGCGATAATTGAAGTTGAAGCTTCGGGTAACAACCGGATAGTAATCTATCC
CGGCGCAAACGCTTATCTTACTGAAAGTGTTGTGGAGTCCGCAAGAGATGAACTTTTGAAAGCGGACGTGCTTTTGTTGC
AGAATGAGATTCCATTTTCTGCAACTCTTCATGCTGCTCGTTTATTTCACGAAGCGGGAAAACTCGTTATTTTCGATCCA
GCACCTTCGAAAGATATAACGAAGGAGATCTTTCAGTACGTTGACATAATCACCCCAAACGAATCGGAAGCAGTTTCACT
GGTAGGTGATTTGCCGCCGGAAATGTTGATTAAGGAACTGAAGAAACTTGGCTGTAAAAATGTACTGTTGAAACTTGGTG
AGAAAGGAACTATCTTTTCTGGAGAACTTGGTGAATTCTCTCTTGGTGCTTTCAAGGTTGATGCAGTAGATACAACCGCT
GCTGGCGATACATTCAACGGGGCTCTCGCGGTAGCTATCGAAAATGGGCTTGACATGATCGATGCGGTTAAATTTGCCAG
TGCCGCTGCTGCAATTTCAGTTACACGTATGGGGGCGCAACCGTCTTGCCCAACACTTGAAGAGGTCAAGTTCTTTCTTG
ATGAACGCGGGGTGAAGATATGA

Upstream 100 bases:

>100_bases
CGGGCTCTATTTATATCCCTGTTGATCTAAAACTTGTTGTGAATGAATAATGGAAAAGGAGGGGGAATGTCCCCCCTCCG
TTTTTTGTGGAGGGATTCGT

Downstream 100 bases:

>100_bases
AGCGCAGCGGAATTATAAACAGGGAGATTGCCAGAATAGCTGCGGAAATGGGGCATATGGACAGAATAACAGTTTGTGAC
TGTGGTTTCCCAATACCTGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIAVVGSNNVDVVLTVDHFTRAGETQKCTTLNYFPGGKGANQAVAAKKLGAEVYFLTCVGNDGNAQFAVESLKKAGLEKG
IKKVDSPNGMAIIEVEASGNNRIVIYPGANAYLTESVVESARDELLKADVLLLQNEIPFSATLHAARLFHEAGKLVIFDP
APSKDITKEIFQYVDIITPNESEAVSLVGDLPPEMLIKELKKLGCKNVLLKLGEKGTIFSGELGEFSLGAFKVDAVDTTA
AGDTFNGALAVAIENGLDMIDAVKFASAAAAISVTRMGAQPSCPTLEEVKFFLDERGVKI

Sequences:

>Translated_300_residues
MIAVVGSNNVDVVLTVDHFTRAGETQKCTTLNYFPGGKGANQAVAAKKLGAEVYFLTCVGNDGNAQFAVESLKKAGLEKG
IKKVDSPNGMAIIEVEASGNNRIVIYPGANAYLTESVVESARDELLKADVLLLQNEIPFSATLHAARLFHEAGKLVIFDP
APSKDITKEIFQYVDIITPNESEAVSLVGDLPPEMLIKELKKLGCKNVLLKLGEKGTIFSGELGEFSLGAFKVDAVDTTA
AGDTFNGALAVAIENGLDMIDAVKFASAAAAISVTRMGAQPSCPTLEEVKFFLDERGVKI
>Mature_300_residues
MIAVVGSNNVDVVLTVDHFTRAGETQKCTTLNYFPGGKGANQAVAAKKLGAEVYFLTCVGNDGNAQFAVESLKKAGLEKG
IKKVDSPNGMAIIEVEASGNNRIVIYPGANAYLTESVVESARDELLKADVLLLQNEIPFSATLHAARLFHEAGKLVIFDP
APSKDITKEIFQYVDIITPNESEAVSLVGDLPPEMLIKELKKLGCKNVLLKLGEKGTIFSGELGEFSLGAFKVDAVDTTA
AGDTFNGALAVAIENGLDMIDAVKFASAAAAISVTRMGAQPSCPTLEEVKFFLDERGVKI

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=302, Percent_Identity=33.112582781457, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=39.6039603960396, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI87082343, Length=296, Percent_Identity=29.0540540540541, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17532905, Length=299, Percent_Identity=31.7725752508361, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=28.7425149700599, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583886, Length=306, Percent_Identity=30.0653594771242, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=32.3529411764706, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31827; Mature: 31827

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVVGSNNVDVVLTVDHFTRAGETQKCTTLNYFPGGKGANQAVAAKKLGAEVYFLTCVG
CEEEEECCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEEC
NDGNAQFAVESLKKAGLEKGIKKVDSPNGMAIIEVEASGNNRIVIYPGANAYLTESVVES
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHH
ARDELLKADVLLLQNEIPFSATLHAARLFHEAGKLVIFDPAPSKDITKEIFQYVDIITPN
HHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCC
ESEAVSLVGDLPPEMLIKELKKLGCKNVLLKLGEKGTIFSGELGEFSLGAFKVDAVDTTA
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCEECCEEEEECCCCCC
AGDTFNGALAVAIENGLDMIDAVKFASAAAAISVTRMGAQPSCPTLEEVKFFLDERGVKI
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIAVVGSNNVDVVLTVDHFTRAGETQKCTTLNYFPGGKGANQAVAAKKLGAEVYFLTCVG
CEEEEECCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEEC
NDGNAQFAVESLKKAGLEKGIKKVDSPNGMAIIEVEASGNNRIVIYPGANAYLTESVVES
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHH
ARDELLKADVLLLQNEIPFSATLHAARLFHEAGKLVIFDPAPSKDITKEIFQYVDIITPN
HHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCC
ESEAVSLVGDLPPEMLIKELKKLGCKNVLLKLGEKGTIFSGELGEFSLGAFKVDAVDTTA
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCEECCEEEEECCCCCC
AGDTFNGALAVAIENGLDMIDAVKFASAAAAISVTRMGAQPSCPTLEEVKFFLDERGVKI
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]