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The map label for this gene is btuR [H]

Identifier: 239616999

GI number: 239616999

Start: 647376

End: 647891

Strand: Reverse

Name: btuR [H]

Synonym: Kole_0599

Alternate gene names: 239616999

Gene position: 647891-647376 (Counterclockwise)

Preceding gene: 239617000

Following gene: 239616998

Centisome position: 28.14

GC content: 41.09

Gene sequence:

>516_bases
ATGGGTAAAGGATATGTTCATGTTTATACAGGAAATGGAAAGGGTAAAACTACTGCGGCATTGGGATTAGCTTTAAGGGC
GGTATGCGCCGGGAAAAAGGTTTTCTTTGGGCAATTTGTTAAAGGAATGGATTACAGTGAACTAAAGGCTGCTAACTTTC
TCCCAAACTTTGTTATAGAGCAATTTGGGAGAGGATGTTTCATACACGGTGAGCCCAGCGACGAAGATGCAAAAGCCGCC
AAAGATGGCCTAAGAAAACTTAAGAATATGCTGGAAGAAGGGAATTTCGATCTGGTGGTAATGGATGAGGTTAATATAGC
GCTCTATTTTAAACTGATAACCTCTTCTGAGGTTATTGAAGCTGTAAATAACCGTGCCGAACATGTAGAAGTGGTTCTTA
CGGGAAGATACGCTCCTCAGGAGATTATTGAGATTGCAGACCTGGTTACCGAAATGAAAGAAGTGAAGCATTACTACCAG
AAAGGGATTATTGCTCGAAAAGGGATTGAATTTTAG

Upstream 100 bases:

>100_bases
TTTTGCTTTCTTTAATCCTCATTTTAAAGCTTATGATTTTTATACCATCGTTAATGATATATTTGAGAGAGAGATACTTA
CCTGGTTAGGGGGCTTAAAG

Downstream 100 bases:

>100_bases
TTTTTAGAACCAAAAGATTTTTGATGTAGTCTTCTCGTTTTTGTATTCGTGTAAATTCGGTAACAAAAACCTGTTTTTTC
AAGATTTACACAATTAACGG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGKGYVHVYTGNGKGKTTAALGLALRAVCAGKKVFFGQFVKGMDYSELKAANFLPNFVIEQFGRGCFIHGEPSDEDAKAA
KDGLRKLKNMLEEGNFDLVVMDEVNIALYFKLITSSEVIEAVNNRAEHVEVVLTGRYAPQEIIEIADLVTEMKEVKHYYQ
KGIIARKGIEF

Sequences:

>Translated_171_residues
MGKGYVHVYTGNGKGKTTAALGLALRAVCAGKKVFFGQFVKGMDYSELKAANFLPNFVIEQFGRGCFIHGEPSDEDAKAA
KDGLRKLKNMLEEGNFDLVVMDEVNIALYFKLITSSEVIEAVNNRAEHVEVVLTGRYAPQEIIEIADLVTEMKEVKHYYQ
KGIIARKGIEF
>Mature_170_residues
GKGYVHVYTGNGKGKTTAALGLALRAVCAGKKVFFGQFVKGMDYSELKAANFLPNFVIEQFGRGCFIHGEPSDEDAKAAK
DGLRKLKNMLEEGNFDLVVMDEVNIALYFKLITSSEVIEAVNNRAEHVEVVLTGRYAPQEIIEIADLVTEMKEVKHYYQK
GIIARKGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=170, Percent_Identity=35.2941176470588, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 18983; Mature: 18852

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGYVHVYTGNGKGKTTAALGLALRAVCAGKKVFFGQFVKGMDYSELKAANFLPNFVIE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHH
QFGRGCFIHGEPSDEDAKAAKDGLRKLKNMLEEGNFDLVVMDEVNIALYFKLITSSEVIE
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEHHHHHHHH
AVNNRAEHVEVVLTGRYAPQEIIEIADLVTEMKEVKHYYQKGIIARKGIEF
HHHCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
GKGYVHVYTGNGKGKTTAALGLALRAVCAGKKVFFGQFVKGMDYSELKAANFLPNFVIE
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHH
QFGRGCFIHGEPSDEDAKAAKDGLRKLKNMLEEGNFDLVVMDEVNIALYFKLITSSEVIE
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEHHHHHHHH
AVNNRAEHVEVVLTGRYAPQEIIEIADLVTEMKEVKHYYQKGIIARKGIEF
HHHCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]