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The map label for this gene is hypE [C]

Identifier: 239616958

GI number: 239616958

Start: 607109

End: 608089

Strand: Reverse

Name: hypE [C]

Synonym: Kole_0556

Alternate gene names: 239616958

Gene position: 608089-607109 (Counterclockwise)

Preceding gene: 239616959

Following gene: 239616957

Centisome position: 26.41

GC content: 41.28

Gene sequence:

>981_bases
TTGAAAGAAAGAATCATAACACTTCACCACAACAGCGGGAAAAAACAGTTTAAGTTACTCAAGCATATAGAGAAACTTCT
TGGAAGTACTTTGGTTTCAACTGAAAATGACAGCGGTTTTTTGGAGGAAGTTGTAGATACTGTTACCACTGACAGTTTCA
CTATCAGTCCCGTGTTCTTTCCCGGCGGAGATATTGGGAAACTTTCCGTGTGCGGTAGCATAAACGATCTTGTAATGACA
GGAGCTAAACCAAAATATATTACCCTTTCAGTTGTTCTCGAAGAAGGATTTGAATTTTCCAGGCTGGATAAAATAATAGA
TTCCATTCGCAAAGAACTCGATGAAAATGGTGTGAAAATCATCGCCGGTGACACAAAGGTAATGGAGCATGGAGCGCTCG
ATAAAATAGTGATCAACACAACGTGCCTGGGAGAGGTTTTATACGAAAAGCTTTGTGTCAAAAGGATAGAAACAAACGAT
TTGATAATTATTACAGGCCCAATTGGTTTGCATGGGGCCGCTATAATGGCTGAAAGAAAGGGATTTCAAATAGATTTTCA
ATCTGATTGCCGGGTACTTACAAAGCTTTTAGCTGTTATAAAAGGGTTGCGTGTTCATGCTATGAGAGATCCGACAAGAG
GTGGCCTTGCCCAGATACTCAACGAATTCTCTCACTCGACAAAAAGAAATTTTGCTATCTATGAAGATAAACTGCCGATA
CCGGGGGGGGTAAAAACCGTTTCAGAGATACTGGGTATCGATCCTCTATACCTCGCATGTGAAGGAACAGCAGTGATTAT
CTGCCACCCTGAAGATGCTCAAGATTTGTTAGAAAGACTTAAAAACGCAGGTTTTGACCCCTCAACGATAGGATTTGTTG
GCGGCATAATTGAGAGACCTTTACTCATCTTGAAAACCCGGAATGGTGCTAAACGTGTGTTACCGATGCTTGTTGAAGAA
CTCACACCGAGGATCTGTTGA

Upstream 100 bases:

>100_bases
ACTCTCTGTTTACCGGAAACGCCCGTTGGTCCATGCATGGTTTCATCAGAAGGGGCCTGTCATGCGAGTTTTCTGTATGG
AAGAAAAGGGGAGTGATAGC

Downstream 100 bases:

>100_bases
AGTTTTTTGATGGGGTGTGGCTGAATTTAAACAAAGAGGAGGAATTGTATGCATCATGAATTATCGATAGCTGAAAGGGT
GAAGATATTCATCGAACAGA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKERIITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDTVTTDSFTISPVFFPGGDIGKLSVCGSINDLVMT
GAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEKLCVKRIETND
LIIITGPIGLHGAAIMAERKGFQIDFQSDCRVLTKLLAVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPI
PGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNAGFDPSTIGFVGGIIERPLLILKTRNGAKRVLPMLVEE
LTPRIC

Sequences:

>Translated_326_residues
MKERIITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDTVTTDSFTISPVFFPGGDIGKLSVCGSINDLVMT
GAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEKLCVKRIETND
LIIITGPIGLHGAAIMAERKGFQIDFQSDCRVLTKLLAVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPI
PGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNAGFDPSTIGFVGGIIERPLLILKTRNGAKRVLPMLVEE
LTPRIC
>Mature_326_residues
MKERIITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDTVTTDSFTISPVFFPGGDIGKLSVCGSINDLVMT
GAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEKLCVKRIETND
LIIITGPIGLHGAAIMAERKGFQIDFQSDCRVLTKLLAVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPI
PGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNAGFDPSTIGFVGGIIERPLLILKTRNGAKRVLPMLVEE
LTPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=336, Percent_Identity=34.2261904761905, Blast_Score=185, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35833; Mature: 35833

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERIITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDTVTTDSFTISPVFF
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEE
PGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKI
CCCCCCCEEECCCCHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
IAGDTKVMEHGALDKIVINTTCLGEVLYEKLCVKRIETNDLIIITGPIGLHGAAIMAERK
EECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHEECCC
GFQIDFQSDCRVLTKLLAVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPI
CCEEECHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
PGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNAGFDPSTIGFVGGIIERP
CCCHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCC
LLILKTRNGAKRVLPMLVEELTPRIC
EEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKERIITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDTVTTDSFTISPVFF
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEE
PGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKI
CCCCCCCEEECCCCHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
IAGDTKVMEHGALDKIVINTTCLGEVLYEKLCVKRIETNDLIIITGPIGLHGAAIMAERK
EECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHEECCC
GFQIDFQSDCRVLTKLLAVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPI
CCEEECHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
PGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNAGFDPSTIGFVGGIIERP
CCCHHHHHHHHCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCC
LLILKTRNGAKRVLPMLVEELTPRIC
EEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]