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The map label for this gene is sgcR [H]

Identifier: 239616568

GI number: 239616568

Start: 177136

End: 177906

Strand: Direct

Name: sgcR [H]

Synonym: Kole_0160

Alternate gene names: 239616568

Gene position: 177136-177906 (Clockwise)

Preceding gene: 239616553

Following gene: 239616569

Centisome position: 7.69

GC content: 38.52

Gene sequence:

>771_bases
ATGAATAAGTCAGAATCGCTCAAAATAATATCAGAAATAATCAGAAAAGAGGGCAATGTATCTATAAAAATGGTATCTGA
AAAGTTGGGTGTTTCAGAATCCACAGCACGGAGATACATAAATGAATTAATCAAAATTTCTTCGCTTCCGTTAAAAAGAG
TGCACGGAGGTGTCATTCTTGACACCGGAAAGGGATCCCTTGAACTCATGTTTGACACCAAATTATCTATGAACGCTGAA
GAAAAGAAAAGAATCGCTCAAAAAGCTGTGAATTTTGTAGAAGATGGCGACAGCATAATCATCGACTCTGGTAGTACAGC
ATTTTACATGGCGAAATATCTCTCGAAAAAACGTGGGATAAAAGTTATATCGGTAGATATCAGGGTAACTGAAGAGTTGG
CAAAAAATCCGGACATAGAAACCTATATAATCGGTGGAATTGTACGTCCAGGATACTACAGCATAGGAGGAGAACTTGCT
GTTGAAACAATAAAGAACTTCTCCGTAGAAAAAGTTTTTTTGACAGTGGACGCGATTGATCTGGAAAACGGAATAACCAA
CTCTTCAATGTTTGAAGTTTACGTTAAAAGAGCACTTATCAACGCAGGAAAAACCGTTATACTTTTGGCCGACAGTTCAA
AGATAGGGAAAAAAGCTTTTGTAAAGGTTGCACCAATAGAAAGCGTGGACATCATAATAACCACGCCTGGAATTGACGCC
GACACTCTAAAGCAACTCGAAGACAAGGGTGTAAGGATCGTGATTGTGTGA

Upstream 100 bases:

>100_bases
GCTTTTAGTGTCTTTATTCTCCCATAGTCTACTTATTTCGTCCTTTTGCTGATTTGCTCACTTTTGACTGAATATGGTAT
ATTTCATACGAGGTGATGAA

Downstream 100 bases:

>100_bases
GGAGGGAAAATATGGCTACTGTAAAGGAAATCTTTGGAAAAGAAAAAGTAATAATTGGTATGGTGCATTTTCCACCGCTT
CCTGGTTCTCCGTTGTATGA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNKSESLKIISEIIRKEGNVSIKMVSEKLGVSESTARRYINELIKISSLPLKRVHGGVILDTGKGSLELMFDTKLSMNAE
EKKRIAQKAVNFVEDGDSIIIDSGSTAFYMAKYLSKKRGIKVISVDIRVTEELAKNPDIETYIIGGIVRPGYYSIGGELA
VETIKNFSVEKVFLTVDAIDLENGITNSSMFEVYVKRALINAGKTVILLADSSKIGKKAFVKVAPIESVDIIITTPGIDA
DTLKQLEDKGVRIVIV

Sequences:

>Translated_256_residues
MNKSESLKIISEIIRKEGNVSIKMVSEKLGVSESTARRYINELIKISSLPLKRVHGGVILDTGKGSLELMFDTKLSMNAE
EKKRIAQKAVNFVEDGDSIIIDSGSTAFYMAKYLSKKRGIKVISVDIRVTEELAKNPDIETYIIGGIVRPGYYSIGGELA
VETIKNFSVEKVFLTVDAIDLENGITNSSMFEVYVKRALINAGKTVILLADSSKIGKKAFVKVAPIESVDIIITTPGIDA
DTLKQLEDKGVRIVIV
>Mature_256_residues
MNKSESLKIISEIIRKEGNVSIKMVSEKLGVSESTARRYINELIKISSLPLKRVHGGVILDTGKGSLELMFDTKLSMNAE
EKKRIAQKAVNFVEDGDSIIIDSGSTAFYMAKYLSKKRGIKVISVDIRVTEELAKNPDIETYIIGGIVRPGYYSIGGELA
VETIKNFSVEKVFLTVDAIDLENGITNSSMFEVYVKRALINAGKTVILLADSSKIGKKAFVKVAPIESVDIIITTPGIDA
DTLKQLEDKGVRIVIV

Specific function: Putative transcriptional regulator for the sgcREAQCX region [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790753, Length=255, Percent_Identity=35.2941176470588, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789059, Length=258, Percent_Identity=34.4961240310078, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=29.2490118577075, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789829, Length=253, Percent_Identity=28.0632411067194, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787540, Length=258, Percent_Identity=29.0697674418605, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788069, Length=254, Percent_Identity=25.9842519685039, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=27.3504273504274, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790635, Length=258, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787063, Length=254, Percent_Identity=22.0472440944882, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789170, Length=240, Percent_Identity=22.0833333333333, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28058; Mature: 28058

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSESLKIISEIIRKEGNVSIKMVSEKLGVSESTARRYINELIKISSLPLKRVHGGVIL
CCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEE
DTGKGSLELMFDTKLSMNAEEKKRIAQKAVNFVEDGDSIIIDSGSTAFYMAKYLSKKRGI
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCC
KVISVDIRVTEELAKNPDIETYIIGGIVRPGYYSIGGELAVETIKNFSVEKVFLTVDAID
EEEEEEEEEHHHHHCCCCCCEEEEECEECCCEEECCHHHHHHHHHCCCEEEEEEEEEEEE
LENGITNSSMFEVYVKRALINAGKTVILLADSSKIGKKAFVKVAPIESVDIIITTPGIDA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCH
DTLKQLEDKGVRIVIV
HHHHHHHHCCCEEEEC
>Mature Secondary Structure
MNKSESLKIISEIIRKEGNVSIKMVSEKLGVSESTARRYINELIKISSLPLKRVHGGVIL
CCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEE
DTGKGSLELMFDTKLSMNAEEKKRIAQKAVNFVEDGDSIIIDSGSTAFYMAKYLSKKRGI
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCC
KVISVDIRVTEELAKNPDIETYIIGGIVRPGYYSIGGELAVETIKNFSVEKVFLTVDAID
EEEEEEEEEHHHHHCCCCCCEEEEECEECCCEEECCHHHHHHHHHCCCEEEEEEEEEEEE
LENGITNSSMFEVYVKRALINAGKTVILLADSSKIGKKAFVKVAPIESVDIIITTPGIDA
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCH
DTLKQLEDKGVRIVIV
HHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]