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The map label for this gene is yxeN [H]

Identifier: 239616532

GI number: 239616532

Start: 139938

End: 140558

Strand: Direct

Name: yxeN [H]

Synonym: Kole_0124

Alternate gene names: 239616532

Gene position: 139938-140558 (Clockwise)

Preceding gene: 239616531

Following gene: 239616533

Centisome position: 6.08

GC content: 47.34

Gene sequence:

>621_bases
ATGACACTGAAATTGACCTTCTGGTCTCTGGGGTTAGGGCTGATTTTAGCCCTCCCCTTTTCTTTCGGCCAGGTTTACGG
TGGAAGAATTGCAAAAGGAATCATCGTTGTGTACGAACGACTCTTTAGAAGTATTCCCCTGCTCGTAATCCTGTTTCTGA
TCTTCTATGGCTTTCCAAAAATAAATGTGAGGTTTTCACCCTTTACGGCCTGTATTCTGGGCCTCGGTTTAAGAAGCGCA
GCGTATCAATCACAGATTTTCAGAGGAGCCATTCAATCGGTGAGTGAAACACAGATGCGTGCAGCGCGATCTCTCGGTAT
GTCGCGTCTTCAGGGCTTCAGACATGTTGTCCTGCCTCAAGCCCTCCGTATCGCACTACCCGGATGGACAAACGAATTCA
CGATTGTTCTCAAAGATTCTTCTCTGGCCTACGCGCTCGGTGTTACAGAGCTTTTGAGGCAGGGGGGCTATATCATTTCA
ACAAAATACGAACCGATGCTCATATACCTGAGTGTTGCTGTCATCTACCTTGTGATAACTTTAGGAATCAACCGGGGTCT
GGGTACTGTGGAGAAAAAACTCGCTATCCCGGGCTTCGCAGTTAAGGAGCAGATAAGATGA

Upstream 100 bases:

>100_bases
GTTGAAAAATACTTCAAGTGATTACGAAAGGCGGTAGAGAGCTATCGAAAAGATAAACATCATTATCGAGGCTTTACCGG
CTCTTCTGAACGGCACATGG

Downstream 100 bases:

>100_bases
GCGGTAAAACTACAAACAAACCATTATTACGGATTGAGAATCTCAAAAAGAGCTTTGGTGATAACGAGGTTTTGAAAGAC
ATTACTTTCTCCGTGAATGA

Product: polar amino acid ABC transporter, inner membrane subunit

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTLKLTFWSLGLGLILALPFSFGQVYGGRIAKGIIVVYERLFRSIPLLVILFLIFYGFPKINVRFSPFTACILGLGLRSA
AYQSQIFRGAIQSVSETQMRAARSLGMSRLQGFRHVVLPQALRIALPGWTNEFTIVLKDSSLAYALGVTELLRQGGYIIS
TKYEPMLIYLSVAVIYLVITLGINRGLGTVEKKLAIPGFAVKEQIR

Sequences:

>Translated_206_residues
MTLKLTFWSLGLGLILALPFSFGQVYGGRIAKGIIVVYERLFRSIPLLVILFLIFYGFPKINVRFSPFTACILGLGLRSA
AYQSQIFRGAIQSVSETQMRAARSLGMSRLQGFRHVVLPQALRIALPGWTNEFTIVLKDSSLAYALGVTELLRQGGYIIS
TKYEPMLIYLSVAVIYLVITLGINRGLGTVEKKLAIPGFAVKEQIR
>Mature_205_residues
TLKLTFWSLGLGLILALPFSFGQVYGGRIAKGIIVVYERLFRSIPLLVILFLIFYGFPKINVRFSPFTACILGLGLRSAA
YQSQIFRGAIQSVSETQMRAARSLGMSRLQGFRHVVLPQALRIALPGWTNEFTIVLKDSSLAYALGVTELLRQGGYIIST
KYEPMLIYLSVAVIYLVITLGINRGLGTVEKKLAIPGFAVKEQIR

Specific function: Probably part of the ABC transporter complex yxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=198, Percent_Identity=36.3636363636364, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1788226, Length=197, Percent_Identity=36.0406091370558, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788645, Length=191, Percent_Identity=35.0785340314136, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788646, Length=207, Percent_Identity=30.9178743961353, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787087, Length=205, Percent_Identity=33.1707317073171, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787086, Length=202, Percent_Identity=31.6831683168317, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786874, Length=186, Percent_Identity=28.494623655914, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786873, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=33.587786259542, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082239, Length=197, Percent_Identity=26.3959390862944, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22850; Mature: 22719

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLTFWSLGLGLILALPFSFGQVYGGRIAKGIIVVYERLFRSIPLLVILFLIFYGFPK
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INVRFSPFTACILGLGLRSAAYQSQIFRGAIQSVSETQMRAARSLGMSRLQGFRHVVLPQ
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ALRIALPGWTNEFTIVLKDSSLAYALGVTELLRQGGYIISTKYEPMLIYLSVAVIYLVIT
HHHEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LGINRGLGTVEKKLAIPGFAVKEQIR
HHCCCCCCHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
TLKLTFWSLGLGLILALPFSFGQVYGGRIAKGIIVVYERLFRSIPLLVILFLIFYGFPK
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INVRFSPFTACILGLGLRSAAYQSQIFRGAIQSVSETQMRAARSLGMSRLQGFRHVVLPQ
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ALRIALPGWTNEFTIVLKDSSLAYALGVTELLRQGGYIISTKYEPMLIYLSVAVIYLVIT
HHHEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LGINRGLGTVEKKLAIPGFAVKEQIR
HHCCCCCCHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]