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The map label for this gene is gufA [H]

Identifier: 239616426

GI number: 239616426

Start: 20454

End: 21197

Strand: Direct

Name: gufA [H]

Synonym: Kole_0015

Alternate gene names: 239616426

Gene position: 20454-21197 (Clockwise)

Preceding gene: 239616425

Following gene: 239616427

Centisome position: 0.89

GC content: 47.58

Gene sequence:

>744_bases
ATGACCCCGGCAATCAAAGGAATTGTTTATAGTTTGATTGCTGGAATGGCTACCTCGATAGGTGCAATTCCCTTTCTTTT
CTGGAAGAAGGGGGTGGATAGGCGTTCTCTCGATATGTTGCTTGGACTTGCCGCCGGCATAATGCTGGCCGCGACAGCTT
TCAGCCTTGTTGTTCCTTCGATACAGATCGGAGGACCGTTTCGCTTTGTTGTTGGATTTATTCTTGGAGCAATCTTCGTC
GATTTAATGGATAAATTCTCACCGCACGAACACTTCATTAAAGGTTACGAAGGCCCAATGACAAAATCAAAACTCTCCAA
GATCTGGTTGTTTGTCATTGCAATAACGCTGCACAACTTTCCAGAAGGCATGGCGGTTGGTGTTGGAGGCTTTACGAAGG
ACGCATTCGCTATCGCAATGGCGATAGGTATTCAAAATATTCCTGAAGGAGCCGCAGTTGCCGGCAGCCTCATCGGCGCC
GGGTACAGTGTCAGGCGCTCTTTCTGGGTGACCTTTCTAACCGGTGCCGTCGAAATTATCGGTGGCGCTCTTGGTGCATT
CCTTATAACGATATCTCAACCTCTGTTGCCGTATGCTATGGCTTTTGCCGGTGGAGCGATGCTGTATGTGATCGGAGATG
AGATAATCCCGGAAACCCACAGTGGGGGATATCAAAGGATCTCAACATATTCTCTTCTCATCGGGTTTATCATAATGACT
CTTCTGGATAATTTGCTCGGTTGA

Upstream 100 bases:

>100_bases
AAAAGACATCTTCTTATTACTATTACTACTACCATTATTACTATACTCAGGATGGAACAAAAAAGAAAATCAGACGAAAA
AAATCCAGGAGGACCGGTGA

Downstream 100 bases:

>100_bases
TTTTGTAGATGTCAGAGGTGATTTTTGTGGAAAATAAAGCTTACAACAGCACTTTCAAAGCTCAACTTTTTATCTATTAT
ATGATGAGTGTGGTGATACC

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTPAIKGIVYSLIAGMATSIGAIPFLFWKKGVDRRSLDMLLGLAAGIMLAATAFSLVVPSIQIGGPFRFVVGFILGAIFV
DLMDKFSPHEHFIKGYEGPMTKSKLSKIWLFVIAITLHNFPEGMAVGVGGFTKDAFAIAMAIGIQNIPEGAAVAGSLIGA
GYSVRRSFWVTFLTGAVEIIGGALGAFLITISQPLLPYAMAFAGGAMLYVIGDEIIPETHSGGYQRISTYSLLIGFIIMT
LLDNLLG

Sequences:

>Translated_247_residues
MTPAIKGIVYSLIAGMATSIGAIPFLFWKKGVDRRSLDMLLGLAAGIMLAATAFSLVVPSIQIGGPFRFVVGFILGAIFV
DLMDKFSPHEHFIKGYEGPMTKSKLSKIWLFVIAITLHNFPEGMAVGVGGFTKDAFAIAMAIGIQNIPEGAAVAGSLIGA
GYSVRRSFWVTFLTGAVEIIGGALGAFLITISQPLLPYAMAFAGGAMLYVIGDEIIPETHSGGYQRISTYSLLIGFIIMT
LLDNLLG
>Mature_246_residues
TPAIKGIVYSLIAGMATSIGAIPFLFWKKGVDRRSLDMLLGLAAGIMLAATAFSLVVPSIQIGGPFRFVVGFILGAIFVD
LMDKFSPHEHFIKGYEGPMTKSKLSKIWLFVIAITLHNFPEGMAVGVGGFTKDAFAIAMAIGIQNIPEGAAVAGSLIGAG
YSVRRSFWVTFLTGAVEIIGGALGAFLITISQPLLPYAMAFAGGAMLYVIGDEIIPETHSGGYQRISTYSLLIGFIIMTL
LDNLLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=154, Percent_Identity=46.7532467532467, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI229577422, Length=154, Percent_Identity=46.7532467532467, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1789419, Length=243, Percent_Identity=32.9218106995885, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507805, Length=301, Percent_Identity=33.5548172757475, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24652846, Length=150, Percent_Identity=46.6666666666667, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 26172; Mature: 26040

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCC
>Mature Secondary Structure 
TPAIKGIVYSLIAGMATSIGAIPFLFWKKGVDRRSLDMLLGLAAGIMLAATAFSLVVPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
IQIGGPFRFVVGFILGAIFVDLMDKFSPHEHFIKGYEGPMTKSKLSKIWLFVIAITLHNF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
PEGMAVGVGGFTKDAFAIAMAIGIQNIPEGAAVAGSLIGAGYSVRRSFWVTFLTGAVEII
CCCCEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GGALGAFLITISQPLLPYAMAFAGGAMLYVIGDEIIPETHSGGYQRISTYSLLIGFIIMT
HHHHHHHHHHHHCHHHHHHHHHHCCEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHH
LLDNLLG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]