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The map label for this gene is gpmA2 [H]

Identifier: 238925516

GI number: 238925516

Start: 3023368

End: 3023922

Strand: Reverse

Name: gpmA2 [H]

Synonym: EUBREC_3172

Alternate gene names: 238925516

Gene position: 3023922-3023368 (Counterclockwise)

Preceding gene: 238925517

Following gene: 238925515

Centisome position: 87.66

GC content: 47.39

Gene sequence:

>555_bases
ATGTTTTATATTTTGCGACATGGAAGAACAGATTGGAATGAGGAGCACAGACTGCAGGGTGAGGTGGATATCCCACTCAA
CGAAACCGGCAGGCAGATGGCTTACGATGCCGCAGAAAAATATAAGGATATAGATTTTGACATATGCTACTGCTCCCCGC
TTAAGAGAGCACAGGAGACGGCAAGGATTTTTCTTGCAGACAGAAACCCTGCAGTAGAGATTATCACTGACAACAGGCTT
CACGAGATGTGCTTCGGTGATTATGAGGGAGTGAAGAACATCAGACAAAAGCCCGAATGCCCTGTATACCTGCTCTTTGA
GGAGCCGGAAAAATATGTGGCAAAGGACGGCGCAGAGAGCTTTGAGGAGCTATATCACAGAACAGGCGAGTTTATAGAGC
AGGTGCTGAGACCGCAGCTTGAGGCAGGCAAAAATGTGCTTGTCGTGGGACACGGTGCAATGAACTGTAGCATAGTCAAT
CAGTTTCGCGGCACACCTATAAAGGATTTCTGGAAGGATATGCAGGGAAACTGCGAGCTGCTTAGGGTTGAATAA

Upstream 100 bases:

>100_bases
TGCCAAATATGATAGCGCTGTTTGCTCTTAGTGGTGTTGTTGTTAAGGAGACAAGGCATTTCTTCGAGAGACATAGAAAT
GGAGAAATCGAGGATTAATT

Downstream 100 bases:

>100_bases
ATTTAGATTATTCTGAATAGTTATATCGTTTGTAATAGATAGGGCATACCGGTTATGGGGTGCCCTATTGCTGTCAGAAA
CTAATTTCAATAGCATTTAT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MFYILRHGRTDWNEEHRLQGEVDIPLNETGRQMAYDAAEKYKDIDFDICYCSPLKRAQETARIFLADRNPAVEIITDNRL
HEMCFGDYEGVKNIRQKPECPVYLLFEEPEKYVAKDGAESFEELYHRTGEFIEQVLRPQLEAGKNVLVVGHGAMNCSIVN
QFRGTPIKDFWKDMQGNCELLRVE

Sequences:

>Translated_184_residues
MFYILRHGRTDWNEEHRLQGEVDIPLNETGRQMAYDAAEKYKDIDFDICYCSPLKRAQETARIFLADRNPAVEIITDNRL
HEMCFGDYEGVKNIRQKPECPVYLLFEEPEKYVAKDGAESFEELYHRTGEFIEQVLRPQLEAGKNVLVVGHGAMNCSIVN
QFRGTPIKDFWKDMQGNCELLRVE
>Mature_184_residues
MFYILRHGRTDWNEEHRLQGEVDIPLNETGRQMAYDAAEKYKDIDFDICYCSPLKRAQETARIFLADRNPAVEIITDNRL
HEMCFGDYEGVKNIRQKPECPVYLLFEEPEKYVAKDGAESFEELYHRTGEFIEQVLRPQLEAGKNVLVVGHGAMNCSIVN
QFRGTPIKDFWKDMQGNCELLRVE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786857, Length=179, Percent_Identity=29.608938547486, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790856, Length=194, Percent_Identity=30.9278350515464, Blast_Score=70, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646216, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 21469; Mature: 21469

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYILRHGRTDWNEEHRLQGEVDIPLNETGRQMAYDAAEKYKDIDFDICYCSPLKRAQET
CEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
ARIFLADRNPAVEIITDNRLHEMCFGDYEGVKNIRQKPECPVYLLFEEPEKYVAKDGAES
HEEEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCHHH
FEELYHRTGEFIEQVLRPQLEAGKNVLVVGHGAMNCSIVNQFRGTPIKDFWKDMQGNCEL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCCEEE
LRVE
EEEC
>Mature Secondary Structure
MFYILRHGRTDWNEEHRLQGEVDIPLNETGRQMAYDAAEKYKDIDFDICYCSPLKRAQET
CEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
ARIFLADRNPAVEIITDNRLHEMCFGDYEGVKNIRQKPECPVYLLFEEPEKYVAKDGAES
HEEEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCHHH
FEELYHRTGEFIEQVLRPQLEAGKNVLVVGHGAMNCSIVNQFRGTPIKDFWKDMQGNCEL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCCEEE
LRVE
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]