Click here to switch to the map view.

The map label for this gene is cpx [H]

Identifier: 238925515

GI number: 238925515

Start: 3021676

End: 3023148

Strand: Reverse

Name: cpx [H]

Synonym: EUBREC_3171

Alternate gene names: 238925515

Gene position: 3023148-3021676 (Counterclockwise)

Preceding gene: 238925516

Following gene: 238925514

Centisome position: 87.64

GC content: 44.87

Gene sequence:

>1473_bases
ATGAAAAAGACAACGAACTCTTCACCTTACCAGTTTGAGGGCAGAATACCTCTGTCTCAGGCTATTCCGCTTGGACTGCA
GCATGTTATGGCTATGTTCATCGGAAACCTTACACCTCTTATCATTGTTATGGGAGCATGCGGGCTCACAGCGGACGCTG
GCTTTGCGGAGCTTAGAACAGCTCTCTTACAGAATGCAATGATTATCGCAGGTATTGTAACATTAGTACAGATGTTTTCC
ATCGGACCTGTCGGAGGAAAGGTACCTATCGTTATGGGAACCTCTTCGGGCTTTCTTGGAGTATTAAATAATACAGTTGC
AGCGTGTGGCGGCGGAGTTATAGCATATGGAGCTATTATGGGAGCCTGCCTTGTAGGAGGTATCTTCGAGGGCATACTCG
GAGCCTTCTTAAAGCCTTTGCGCAAGTTTTTCCCGGCAATCGTTACAGGCTCAGTTGTTATAGCAATCGGACTTTCACTC
CTTGGAGTGGGAATCAACTACTTCTGTGGTGGAACAGGCAAAAATGATTACGGCTCACTGCCAAACCTTTTTATTGGAAT
GGTTGTACTTATAGTAATCGTGCTTCTTAAGCATTTTGCACCATCGCGCAGTATTTTTTCATCATCTGCCATCCTTTTTG
GTATCCTGGCAGGATATGTTGTAGCAATCATTATGACACTTACCATGTCACACACAGGTGTGACCGCTGACGGTGTTAAA
TACACATACTCATGGGTTGTAAACTTTGATGAGGTTAAAAATGCGGCATGGATAGCAGTTCCAAGCTTTATAGGTTTTGG
AAAGTTGTCAGATGTGGGAATTTCCTTCCATGCCAATGCAATCATCCCAATCGGTATCATGTTTATCGTTACTGCAATCG
AGACAGTTGGCGATATTTCAGCCTGTGTGGAGGGTGGAATGGACAGAGAGGCTACAGATTCAGAGCTTTCAGGCGGTGTT
ATCTGTGATGGTCTTGGTTCATCATTTGCAGCGCTTTTCGGAGTACTGCCAAATACCTCATTCTCACAGAATGTAGGTCT
TGTTTCAATGACAAAGGTTGTCAATAGATTTGCTATTTCAATGGGAGCTATATTCCTCGTTATTTGCGGCTTCTGCCCAA
AGATTGGAGCTCTCATGTCAATCATGCCTCAGTCAGTGCTCGGCGGAGCTGCTGTTATGATGTTTGCCTCTATCCTGATT
TCGGGAATTGAGCTCATCACAAAGGAGCCAATCGGCAGCCGTGAGATTACAATTATCTCAGTAGCAATCGGTTTAGGCTA
CGGACTTGGCGCTACAACCGGTGCTACATCACATCTGCCATACTATGTACAGCTTATATTTGGCGGTTCAGGTATCGTGC
CTTGCTCACTTTGCGCTATTCTTCTCAATATTATTTTGCCGAAGAAGTCAAAGAACGCGCCATATATGTGGGATATGGAC
GAGAAAGACGATGTGAAGCGTGTGGATGACTAA

Upstream 100 bases:

>100_bases
ATATTATAAGTAATACTAAATTGACCACATAGCCTTATGCTCGTAAAATAATTTTGTAAATTTTTTATTAAATTAAGAGT
ATAATTATTTGGAGGAACCA

Downstream 100 bases:

>100_bases
CGCTTAGGATTTTGAAGCCGTCCGGTGCATTAAGTACACCGGCGGCTTTATTGTTTGTGGGAAAGTATGGAAATATATGG
AAAAAGTGATTTCAATAGTG

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MKKTTNSSPYQFEGRIPLSQAIPLGLQHVMAMFIGNLTPLIIVMGACGLTADAGFAELRTALLQNAMIIAGIVTLVQMFS
IGPVGGKVPIVMGTSSGFLGVLNNTVAACGGGVIAYGAIMGACLVGGIFEGILGAFLKPLRKFFPAIVTGSVVIAIGLSL
LGVGINYFCGGTGKNDYGSLPNLFIGMVVLIVIVLLKHFAPSRSIFSSSAILFGILAGYVVAIIMTLTMSHTGVTADGVK
YTYSWVVNFDEVKNAAWIAVPSFIGFGKLSDVGISFHANAIIPIGIMFIVTAIETVGDISACVEGGMDREATDSELSGGV
ICDGLGSSFAALFGVLPNTSFSQNVGLVSMTKVVNRFAISMGAIFLVICGFCPKIGALMSIMPQSVLGGAAVMMFASILI
SGIELITKEPIGSREITIISVAIGLGYGLGATTGATSHLPYYVQLIFGGSGIVPCSLCAILLNIILPKKSKNAPYMWDMD
EKDDVKRVDD

Sequences:

>Translated_490_residues
MKKTTNSSPYQFEGRIPLSQAIPLGLQHVMAMFIGNLTPLIIVMGACGLTADAGFAELRTALLQNAMIIAGIVTLVQMFS
IGPVGGKVPIVMGTSSGFLGVLNNTVAACGGGVIAYGAIMGACLVGGIFEGILGAFLKPLRKFFPAIVTGSVVIAIGLSL
LGVGINYFCGGTGKNDYGSLPNLFIGMVVLIVIVLLKHFAPSRSIFSSSAILFGILAGYVVAIIMTLTMSHTGVTADGVK
YTYSWVVNFDEVKNAAWIAVPSFIGFGKLSDVGISFHANAIIPIGIMFIVTAIETVGDISACVEGGMDREATDSELSGGV
ICDGLGSSFAALFGVLPNTSFSQNVGLVSMTKVVNRFAISMGAIFLVICGFCPKIGALMSIMPQSVLGGAAVMMFASILI
SGIELITKEPIGSREITIISVAIGLGYGLGATTGATSHLPYYVQLIFGGSGIVPCSLCAILLNIILPKKSKNAPYMWDMD
EKDDVKRVDD
>Mature_490_residues
MKKTTNSSPYQFEGRIPLSQAIPLGLQHVMAMFIGNLTPLIIVMGACGLTADAGFAELRTALLQNAMIIAGIVTLVQMFS
IGPVGGKVPIVMGTSSGFLGVLNNTVAACGGGVIAYGAIMGACLVGGIFEGILGAFLKPLRKFFPAIVTGSVVIAIGLSL
LGVGINYFCGGTGKNDYGSLPNLFIGMVVLIVIVLLKHFAPSRSIFSSSAILFGILAGYVVAIIMTLTMSHTGVTADGVK
YTYSWVVNFDEVKNAAWIAVPSFIGFGKLSDVGISFHANAIIPIGIMFIVTAIETVGDISACVEGGMDREATDSELSGGV
ICDGLGSSFAALFGVLPNTSFSQNVGLVSMTKVVNRFAISMGAIFLVICGFCPKIGALMSIMPQSVLGGAAVMMFASILI
SGIELITKEPIGSREITIISVAIGLGYGLGATTGATSHLPYYVQLIFGGSGIVPCSLCAILLNIILPKKSKNAPYMWDMD
EKDDVKRVDD

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790087, Length=480, Percent_Identity=28.125, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI87082181, Length=470, Percent_Identity=29.7872340425532, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87082178, Length=489, Percent_Identity=30.6748466257669, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081818, Length=487, Percent_Identity=25.4620123203285, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788843, Length=403, Percent_Identity=26.7990074441687, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=403, Percent_Identity=24.8138957816377, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=436, Percent_Identity=22.0183486238532, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=410, Percent_Identity=24.8780487804878, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=235, Percent_Identity=26.3829787234043, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50934; Mature: 50934

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]