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The map label for this gene is hcrC [H]

Identifier: 238925499

GI number: 238925499

Start: 3007681

End: 3008214

Strand: Reverse

Name: hcrC [H]

Synonym: EUBREC_3155

Alternate gene names: 238925499

Gene position: 3008214-3007681 (Counterclockwise)

Preceding gene: 238925500

Following gene: 238925498

Centisome position: 87.2

GC content: 46.07

Gene sequence:

>534_bases
ATGGATGTTAAAATAAAATTAAATGGAAAGTTAATAACCGACTCGGTAGACCAGGATATGGTCCTTTTAGACTTTTGCCG
TAAGCACAATTGCTTTTCGGTGAAGAGAGGCTGTGAGTCAGGCAACTGTGGTCTTTGTACAGTGCTTCTGGATGGAAAGC
CTGTGCTGTCATGCAGCACGCCGATAGGCAGGGCAGACGGCAGAGCGGTGGACACCCTCGAGGGACTTGAGGAGGAAGCT
AAGCAGTTTACAGGATTTTTTGCTGCACAGGGAGCGGATCAGTGCGGCTTTTGTAATCCGGGTTATATTGTAAATATTGT
GGCGCTTCTGAGAGAAAATCCTGACCCGACTGATGAGGAAATTCTTGAATATCTTTCAGGAAATCTGTGCCGTTGTACAG
GATATCAGAGTCAGCTCCGCTCAATCAGAAATTTCTTAAACAGTAAGAAAGAGGGCGCACCTCTTAATCTTGAGGCAGGC
GTCTATGGAGAGGATATCGGAAAGGAGTGGCAGGATGAGCACAAATCAAACTAA

Upstream 100 bases:

>100_bases
AGATAATCTGCAGGGTGCTTACACGCCGCGCTGTTACACAGTCGCTTGACATCTGCGATGATATTAAGCACGAGCATTAA
GTAGGAAGGAATTCATATAT

Downstream 100 bases:

>100_bases
TGAAAACAGCTTCAACCGCGCCAGAAGGGATTACCACGCGGTTGGAAAATGTATACCTAAAAAGGACTCGAGCCAGCTTT
TACTCGGAAAGCCGGTATTT

Product: [2Fe-2S] binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MDVKIKLNGKLITDSVDQDMVLLDFCRKHNCFSVKRGCESGNCGLCTVLLDGKPVLSCSTPIGRADGRAVDTLEGLEEEA
KQFTGFFAAQGADQCGFCNPGYIVNIVALLRENPDPTDEEILEYLSGNLCRCTGYQSQLRSIRNFLNSKKEGAPLNLEAG
VYGEDIGKEWQDEHKSN

Sequences:

>Translated_177_residues
MDVKIKLNGKLITDSVDQDMVLLDFCRKHNCFSVKRGCESGNCGLCTVLLDGKPVLSCSTPIGRADGRAVDTLEGLEEEA
KQFTGFFAAQGADQCGFCNPGYIVNIVALLRENPDPTDEEILEYLSGNLCRCTGYQSQLRSIRNFLNSKKEGAPLNLEAG
VYGEDIGKEWQDEHKSN
>Mature_177_residues
MDVKIKLNGKLITDSVDQDMVLLDFCRKHNCFSVKRGCESGNCGLCTVLLDGKPVLSCSTPIGRADGRAVDTLEGLEEEA
KQFTGFFAAQGADQCGFCNPGYIVNIVALLRENPDPTDEEILEYLSGNLCRCTGYQSQLRSIRNFLNSKKEGAPLNLEAG
VYGEDIGKEWQDEHKSN

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=92, Percent_Identity=40.2173913043478, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI71773480, Length=154, Percent_Identity=30.5194805194805, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789232, Length=154, Percent_Identity=37.6623376623377, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=37.9084967320261, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.2549019607843, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=36.3636363636364, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647199, Length=160, Percent_Identity=33.125, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647201, Length=161, Percent_Identity=32.2981366459627, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647193, Length=163, Percent_Identity=30.0613496932515, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647197, Length=166, Percent_Identity=29.5180722891566, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647195, Length=166, Percent_Identity=29.5180722891566, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 19445; Mature: 19445

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKIKLNGKLITDSVDQDMVLLDFCRKHNCFSVKRGCESGNCGLCTVLLDGKPVLSCST
CCEEEEECCEEEECCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCEEEEEECCCEEEEECC
PIGRADGRAVDTLEGLEEEAKQFTGFFAAQGADQCGFCNPGYIVNIVALLRENPDPTDEE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHH
ILEYLSGNLCRCTGYQSQLRSIRNFLNSKKEGAPLNLEAGVYGEDIGKEWQDEHKSN
HHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVKIKLNGKLITDSVDQDMVLLDFCRKHNCFSVKRGCESGNCGLCTVLLDGKPVLSCST
CCEEEEECCEEEECCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCEEEEEECCCEEEEECC
PIGRADGRAVDTLEGLEEEAKQFTGFFAAQGADQCGFCNPGYIVNIVALLRENPDPTDEE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHH
ILEYLSGNLCRCTGYQSQLRSIRNFLNSKKEGAPLNLEAGVYGEDIGKEWQDEHKSN
HHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]