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The map label for this gene is fabZ2 [H]

Identifier: 238925486

GI number: 238925486

Start: 2994051

End: 2994485

Strand: Reverse

Name: fabZ2 [H]

Synonym: EUBREC_3142

Alternate gene names: 238925486

Gene position: 2994485-2994051 (Counterclockwise)

Preceding gene: 238925487

Following gene: 238925485

Centisome position: 86.8

GC content: 47.36

Gene sequence:

>435_bases
ATGTATATGTCAATTATGAATACGCAGCAGATTATGGATATTCTGCCGCACCGCAGTCCGTTTCTTCTCATTGATACGGT
TGAGGAGCTGCAGCCGGGCGTGAAGTGTGTGGCTAAGAAGAATGTGACTATGAATGAGCCACATTTTATGGGACATTTTC
CGGGAAATCCGGTGATGCCGGGAGTGCTTATTATTGAGGCTTTGGCGCAGACAGGTGCAGTTGCCATTCTTTGTCAGGAT
GAGTGGAAGGGCAAGACTGCATATTTTGCAGGCATCAATAATGCCAAGTTCAAGCAGAAGGTGGTTCCGGGAGATACTCT
GGAGTTGACCACTGAGATTATAAAGGTTAAGGGTCCTATCGGTGTGGGCAAGGCTGTTGCCAGGGTAAATGGCAAGGTTG
CCTGTATGGCGGAGCTTACATTTGCAATAGGTTAA

Upstream 100 bases:

>100_bases
ACAGTTCATATTTTTCATTCAGAACACACTGTGCGCTTTCCGGTCCACTTTGTTGAGCGCGAAGCGTGTAGATAGTTTAG
AGCGAATTGAGAAAGGATAG

Downstream 100 bases:

>100_bases
TTGCATAAGGAGACATGATGAAGTTATTCAAGAAGAAAGATAAAAATATAGAGGCTGAAGAGACTTTAGCAAAGAACGCT
GAGAGCGAAAAAACAGCCGC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase 2 [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MYMSIMNTQQIMDILPHRSPFLLIDTVEELQPGVKCVAKKNVTMNEPHFMGHFPGNPVMPGVLIIEALAQTGAVAILCQD
EWKGKTAYFAGINNAKFKQKVVPGDTLELTTEIIKVKGPIGVGKAVARVNGKVACMAELTFAIG

Sequences:

>Translated_144_residues
MYMSIMNTQQIMDILPHRSPFLLIDTVEELQPGVKCVAKKNVTMNEPHFMGHFPGNPVMPGVLIIEALAQTGAVAILCQD
EWKGKTAYFAGINNAKFKQKVVPGDTLELTTEIIKVKGPIGVGKAVARVNGKVACMAELTFAIG
>Mature_144_residues
MYMSIMNTQQIMDILPHRSPFLLIDTVEELQPGVKCVAKKNVTMNEPHFMGHFPGNPVMPGVLIIEALAQTGAVAILCQD
EWKGKTAYFAGINNAKFKQKVVPGDTLELTTEIIKVKGPIGVGKAVARVNGKVACMAELTFAIG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=45.5882352941176, Blast_Score=121, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15597; Mature: 15597

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMSIMNTQQIMDILPHRSPFLLIDTVEELQPGVKCVAKKNVTMNEPHFMGHFPGNPVMP
CEEECCCHHHHHHHHCCCCCEEEEECHHHHCCCCEEEHCCCCCCCCCEEEEECCCCCCCC
GVLIIEALAQTGAVAILCQDEWKGKTAYFAGINNAKFKQKVVPGDTLELTTEIIKVKGPI
HHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCEEECCCCCHHHHEEEEEEECCCC
GVGKAVARVNGKVACMAELTFAIG
CCCHHHHHCCCCEEEEEEEEEECC
>Mature Secondary Structure
MYMSIMNTQQIMDILPHRSPFLLIDTVEELQPGVKCVAKKNVTMNEPHFMGHFPGNPVMP
CEEECCCHHHHHHHHCCCCCEEEEECHHHHCCCCEEEHCCCCCCCCCEEEEECCCCCCCC
GVLIIEALAQTGAVAILCQDEWKGKTAYFAGINNAKFKQKVVPGDTLELTTEIIKVKGPI
HHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCEEECCCCCHHHHEEEEEEECCCC
GVGKAVARVNGKVACMAELTFAIG
CCCHHHHHCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]