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The map label for this gene is ribH

Identifier: 238925474

GI number: 238925474

Start: 2983029

End: 2983493

Strand: Reverse

Name: ribH

Synonym: EUBREC_3129

Alternate gene names: 238925474

Gene position: 2983493-2983029 (Counterclockwise)

Preceding gene: 238925475

Following gene: 238925473

Centisome position: 86.49

GC content: 44.52

Gene sequence:

>465_bases
ATGAACGTAATCGAAGGAAAAATGACACAGGATGGAATCAAGGTAGGAATCGTAGTAGCAAGATTCAATGAATTTATCAC
ATCAAAGCTCTTAGGAGGAGCAAAGGACGGACTCGTAAGACACGACGTGCCGGAGGAAAACATAGACGTAGCATGGGTGC
CGGGAGCATTCGAGATACCACTCATCGCAAAGAAGATGGCAAAAAGTAGAAAATACGATGCAATCATCTGCCTCGGAGCA
GTAATCAGAGGCGCAACAAGCCACTATGACTATGTGTGCAACGAGGTATCAAAGGGAATCGCATCAGTATCACTCGAATC
AGAAATCCCGGTAATGTTTGGAGTAGTCACCACTGAAAACATCGAGCAGGCAATAGAAAGAGCCGGAACAAAAGCCGGAA
ACAAAGGATATGACTGTGCACTCGGTGCAATCGAAATGATAAATCTCGTTAGACAAATCGGATAA

Upstream 100 bases:

>100_bases
CGCCACAGCGCATGACCTGTTTTATCTGAAAACAAAGCAGAACCGCATGGGACATATACTCTCATACTAGCAAAAATAAA
AAAACAAAAGGAGAACAAAA

Downstream 100 bases:

>100_bases
TATAATTATATAGCATAATCCCAGAGGGTCAAATATCATCGATATTTGACCCTCGAATATTTATTATATCTCAAATTGTA
AATTATTGTCACAACGTAAG

Product: riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase)

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIPLIAKKMAKSRKYDAIICLGA
VIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTENIEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG

Sequences:

>Translated_154_residues
MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIPLIAKKMAKSRKYDAIICLGA
VIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTENIEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG
>Mature_154_residues
MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIPLIAKKMAKSRKYDAIICLGA
VIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTENIEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=154, Percent_Identity=57.7922077922078, Blast_Score=179, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6324429, Length=143, Percent_Identity=32.1678321678322, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_EUBR3 (C4Z8N0)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002938991.1
- GeneID:   7965308
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_3129
- ProtClustDB:   CLSK2548480
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16569; Mature: 16569

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIP
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCH
LIAKKMAKSRKYDAIICLGAVIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTEN
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHH
IEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIP
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCH
LIAKKMAKSRKYDAIICLGAVIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTEN
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHH
IEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA