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The map label for this gene is ttdA [H]

Identifier: 238925426

GI number: 238925426

Start: 2945994

End: 2946893

Strand: Reverse

Name: ttdA [H]

Synonym: EUBREC_3081

Alternate gene names: 238925426

Gene position: 2946893-2945994 (Counterclockwise)

Preceding gene: 238925427

Following gene: 238925425

Centisome position: 85.42

GC content: 43.22

Gene sequence:

>900_bases
ATGTCAAACGAGAAACAGGTAGAACAGCTTACCACCTATATGGCAAATTTTATCGCTCATATAGCAAAAAAATTACCGGA
TGATGTCATTGCAAAACTGACAGAACTCCGTGACAAAGAGGACAGTCCTCTTTCAAAAACAATCTATGATACAATGTTTA
GAAATCAGGAGCTTGCGGTAAAACTTAACCGCCCAAGCTGCCAGGATACAGGAGTACTTCAGTTCTGGGTTAAATGTGGA
ACAAAATTCCCACTTATTGATGAGCTTGAGGGACTTTTAAAAGAGGCAGTTGTAAAAGCTACATTTGAGGCTCCTCTTCG
TCACAACAGTGTTGAGACTTTCGATGAGTACAACACAGGCAAGAACGTTGGAAAAGGAACACCTACAGTATTCTGGGATA
TCGTGCCAAACAGTGACAAATGTGAGATCTACACATACATGGCAGGAGGTGGATGTACACTTCCGGGAAAAGCTATGGTA
CTTATGCCTGGAGAGGGCTATGAAGGAGTTACAAAATTCGTAATGGATGTTATGACTACTTATGGTTTAAATGCATGCCC
ACCTCTCCTGGTAGGTGTAGGTGTAGCAACATCTGTTGAGACAGCAGCACTTTTATCAAAGAAAGCACTCATGCGTCCAA
TCGGATCTCACAATGAGAACGAGAGAGCTGCAAAGATGGAAACACTTCTCGAGGATGGTATCAATGCTATCGGCCTTGGA
CCTCAGGGAATGGGCGGAAAATACTCAGTAATGGGTGTAAATATCGAGAACACAGCCCGTCATCCATCTACAATCGGTGT
AGCCGTAAACGTAGGCTGCTGGAGCCACAGACGCGGACACATTGTTTTTGATAAGGACCTTAACTATACAATCACAACAC
ATTCGGGGGTGGAATTATAA

Upstream 100 bases:

>100_bases
GCCGATTTTCTATCCGTTCTTCCCATAAGAACGGATGGGAGTGGGTAAACAATAAATTAATATTTAATTATTTACAAGAT
TTATATTAGGAGGAAAAACT

Downstream 100 bases:

>100_bases
TGGTAGAGAGAATTAATGGAAAAACAATTTTAACAACACCAATCTCAGCAGAGGATCTTAAAGGAATAAAAATCGGAGAT
ATTGTATACTTAAATGGAAG

Product: tartrate dehydratase subunit alpha

Products: NA

Alternate protein names: L-TTD alpha [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSNEKQVEQLTTYMANFIAHIAKKLPDDVIAKLTELRDKEDSPLSKTIYDTMFRNQELAVKLNRPSCQDTGVLQFWVKCG
TKFPLIDELEGLLKEAVVKATFEAPLRHNSVETFDEYNTGKNVGKGTPTVFWDIVPNSDKCEIYTYMAGGGCTLPGKAMV
LMPGEGYEGVTKFVMDVMTTYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAAKMETLLEDGINAIGLG
PQGMGGKYSVMGVNIENTARHPSTIGVAVNVGCWSHRRGHIVFDKDLNYTITTHSGVEL

Sequences:

>Translated_299_residues
MSNEKQVEQLTTYMANFIAHIAKKLPDDVIAKLTELRDKEDSPLSKTIYDTMFRNQELAVKLNRPSCQDTGVLQFWVKCG
TKFPLIDELEGLLKEAVVKATFEAPLRHNSVETFDEYNTGKNVGKGTPTVFWDIVPNSDKCEIYTYMAGGGCTLPGKAMV
LMPGEGYEGVTKFVMDVMTTYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAAKMETLLEDGINAIGLG
PQGMGGKYSVMGVNIENTARHPSTIGVAVNVGCWSHRRGHIVFDKDLNYTITTHSGVEL
>Mature_298_residues
SNEKQVEQLTTYMANFIAHIAKKLPDDVIAKLTELRDKEDSPLSKTIYDTMFRNQELAVKLNRPSCQDTGVLQFWVKCGT
KFPLIDELEGLLKEAVVKATFEAPLRHNSVETFDEYNTGKNVGKGTPTVFWDIVPNSDKCEIYTYMAGGGCTLPGKAMVL
MPGEGYEGVTKFVMDVMTTYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAAKMETLLEDGINAIGLGP
QGMGGKYSVMGVNIENTARHPSTIGVAVNVGCWSHRRGHIVFDKDLNYTITTHSGVEL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=295, Percent_Identity=58.9830508474576, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1790564, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787897, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 32680; Mature: 32549

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEKQVEQLTTYMANFIAHIAKKLPDDVIAKLTELRDKEDSPLSKTIYDTMFRNQELAV
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEE
KLNRPSCQDTGVLQFWVKCGTKFPLIDELEGLLKEAVVKATFEAPLRHNSVETFDEYNTG
EECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
KNVGKGTPTVFWDIVPNSDKCEIYTYMAGGGCTLPGKAMVLMPGEGYEGVTKFVMDVMTT
CCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAAKMETLLEDGINAIGLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECC
PQGMGGKYSVMGVNIENTARHPSTIGVAVNVGCWSHRRGHIVFDKDLNYTITTHSGVEL
CCCCCCEEEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCC
>Mature Secondary Structure 
SNEKQVEQLTTYMANFIAHIAKKLPDDVIAKLTELRDKEDSPLSKTIYDTMFRNQELAV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEE
KLNRPSCQDTGVLQFWVKCGTKFPLIDELEGLLKEAVVKATFEAPLRHNSVETFDEYNTG
EECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
KNVGKGTPTVFWDIVPNSDKCEIYTYMAGGGCTLPGKAMVLMPGEGYEGVTKFVMDVMTT
CCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHNENERAAKMETLLEDGINAIGLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECC
PQGMGGKYSVMGVNIENTARHPSTIGVAVNVGCWSHRRGHIVFDKDLNYTITTHSGVEL
CCCCCCEEEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]