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The map label for this gene is ykoW [H]

Identifier: 238925306

GI number: 238925306

Start: 2843319

End: 2845208

Strand: Reverse

Name: ykoW [H]

Synonym: EUBREC_2960

Alternate gene names: 238925306

Gene position: 2845208-2843319 (Counterclockwise)

Preceding gene: 238925309

Following gene: 238925305

Centisome position: 82.48

GC content: 39.42

Gene sequence:

>1890_bases
ATGAATATTGTTTCACAAATGTGTGCCATTGCGGTGATGTTCGTAATAATGTATTTTTATATTTCGCAGAAAAAGATTAT
ATTACATACATCGAAGGCTTTTGTTGAGGTATGGATTGCAGGCTTGCTGTCACTTTTCTCTGATATTTTCGCACTTGTTG
CAATTGAAAAAAGAAGCGGATATCCTCATACTGCTACCAATATTATCTGCAAATTATATCTCTGGACGGTTACATGGGTT
GCCATGGTGGCCTTCTGGTATATATGCGTGGATATTTTCAGGAAAAAAGAGCTTGAGCGCAAGTGGAGAAAGCGGCTGTG
GATATTTGGAATCTTAACTGATATTCTGATAATGGTCGTACCGATTAAAATTTATGATTCGGATAATATAGTTTATACAT
ATGGTCCGGCTGTTATTATAACATATGCAGTAACTGTAATTCTGCTGGCGCTTATTCTAATGCTGACAAAAAAATACAGT
CAGGCTATAAATCCGAGAAGAAGAAAGAGCATGCAGGTCTGGGTGGCTCTTATGTTTATATCGGCGGTTATTCAGTTTAT
AGATAAAAAAATATTGATTGTCAGCTTTGCGAGTGTGATAGGTGTGCTTATCCTTTTTATTATGCTTGAAAATCCAATGG
CAAATATTGACAGGGATACAGGATTTTTCAACCTCAATGCCCTTTTTGAATACATGAAGGAGGCATATGGACAGGGGAAT
GATGTATCGATAGTGTGTATTCGCTATGGAAGCAATGAAAATGATTTTTTCACCCGCGAGATGGAAAAAAGTATTTTTTA
TGAGGTGGTTTCTTTTATAAATAAGCTGCCTGATAATTATGTTTTTAGAAGCTCGGCAAACGAGTATCTGCTGGTTTTTG
AGAATACTGATTGTGCAGAAAAAACAATCGGAATATTGGAACGCAGGTTCGACAAGCCATGGGGCGGTGACAATATGACG
ATGCTGTTTGGGGAAATATATTATCTAAGGTCTACTGAGCTTGTGCGGAGACCATCGGATATACTGGGGCTTTTTCAATA
TGCCAAGCGTAACAGAGCTGAGTTTACGGGGCGCGGCGTGATGCTCATAAATAATGAAGTCATTGAGCACATATATGATG
AAAATTCGGTTGAGAATGAGATAATAGAGGCATTGCGCGATAACCGTGTTGAGGTATTTTACCAGCCTATTTATAACACT
AAAACGCATAAATTCACCTCTGCGGAGGCGCTTGTCAGAATAAGGTCGCGCGAGGGAAATATCATACCTCCGGGCAGGTT
TATTGCTGTAGCTGAGAAGCGGGGACTCATTTTAAGGCTTGGAGAGCGCGTGTTTGAGATAGTGTGCAGATTTATTGTAC
AGCATGATATACATGCGATGGGAATTGAGTATATTGAATGCAACCTGTCAGTGGTGCAGTGTGCTTATGACCATTTAGCG
CAGGATTTTATTGCAATTATGGAGAAATATCATGTGGATGCAAATGATATTGTGCTTGAGATTACAGAGTCTGCATCTAT
CACTGAAAAAAAGATACTGCTTGATAATATGAATGCCCTGCGTAAGGTGGGAGTGAGGTTTGCGCTGGATGATTTTGGCA
CAGGTCAGTCAAATTTAAGCTATATTGTTGATATGCCGATTGACATTGTGAAATTTGACAGAGGCATGACAAATGCATAT
TTTGACAACGGAAAGGGCAAGCCGGTTATGGATGCCGCAATGGGCATGATTCAAAAGCTTAAGCTTGAGATTGTTTCTGA
GGGAATTGAGGAGAAGGAGCAGTTGGCAAAGCTGGATGAGCTTGGAATAGATTACATTCAGGGCTACTATTTCTCAAAAC
CGAGAAATGCTGCTGAGTTTATTTCATTCATAGAAAGCAATAATACATAG

Upstream 100 bases:

>100_bases
CTTTGTAAATCAAAACAATATATTGCTTTATTGGTAAAATAACGGTAAAATAGTACTAGGGTATTGGTTTGGTTTAGGAA
AGGTTCAGGAAATAGGGGAT

Downstream 100 bases:

>100_bases
TTTATTTCATTCATAGAAAGCAATAATGCATAGTTTATTTCATTCATAGAAAGCAATAATGCATAGTTTATTTTATTCAT
ACAAGATAATAATGATATGA

Product: sensory transduction protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MNIVSQMCAIAVMFVIMYFYISQKKIILHTSKAFVEVWIAGLLSLFSDIFALVAIEKRSGYPHTATNIICKLYLWTVTWV
AMVAFWYICVDIFRKKELERKWRKRLWIFGILTDILIMVVPIKIYDSDNIVYTYGPAVIITYAVTVILLALILMLTKKYS
QAINPRRRKSMQVWVALMFISAVIQFIDKKILIVSFASVIGVLILFIMLENPMANIDRDTGFFNLNALFEYMKEAYGQGN
DVSIVCIRYGSNENDFFTREMEKSIFYEVVSFINKLPDNYVFRSSANEYLLVFENTDCAEKTIGILERRFDKPWGGDNMT
MLFGEIYYLRSTELVRRPSDILGLFQYAKRNRAEFTGRGVMLINNEVIEHIYDENSVENEIIEALRDNRVEVFYQPIYNT
KTHKFTSAEALVRIRSREGNIIPPGRFIAVAEKRGLILRLGERVFEIVCRFIVQHDIHAMGIEYIECNLSVVQCAYDHLA
QDFIAIMEKYHVDANDIVLEITESASITEKKILLDNMNALRKVGVRFALDDFGTGQSNLSYIVDMPIDIVKFDRGMTNAY
FDNGKGKPVMDAAMGMIQKLKLEIVSEGIEEKEQLAKLDELGIDYIQGYYFSKPRNAAEFISFIESNNT

Sequences:

>Translated_629_residues
MNIVSQMCAIAVMFVIMYFYISQKKIILHTSKAFVEVWIAGLLSLFSDIFALVAIEKRSGYPHTATNIICKLYLWTVTWV
AMVAFWYICVDIFRKKELERKWRKRLWIFGILTDILIMVVPIKIYDSDNIVYTYGPAVIITYAVTVILLALILMLTKKYS
QAINPRRRKSMQVWVALMFISAVIQFIDKKILIVSFASVIGVLILFIMLENPMANIDRDTGFFNLNALFEYMKEAYGQGN
DVSIVCIRYGSNENDFFTREMEKSIFYEVVSFINKLPDNYVFRSSANEYLLVFENTDCAEKTIGILERRFDKPWGGDNMT
MLFGEIYYLRSTELVRRPSDILGLFQYAKRNRAEFTGRGVMLINNEVIEHIYDENSVENEIIEALRDNRVEVFYQPIYNT
KTHKFTSAEALVRIRSREGNIIPPGRFIAVAEKRGLILRLGERVFEIVCRFIVQHDIHAMGIEYIECNLSVVQCAYDHLA
QDFIAIMEKYHVDANDIVLEITESASITEKKILLDNMNALRKVGVRFALDDFGTGQSNLSYIVDMPIDIVKFDRGMTNAY
FDNGKGKPVMDAAMGMIQKLKLEIVSEGIEEKEQLAKLDELGIDYIQGYYFSKPRNAAEFISFIESNNT
>Mature_629_residues
MNIVSQMCAIAVMFVIMYFYISQKKIILHTSKAFVEVWIAGLLSLFSDIFALVAIEKRSGYPHTATNIICKLYLWTVTWV
AMVAFWYICVDIFRKKELERKWRKRLWIFGILTDILIMVVPIKIYDSDNIVYTYGPAVIITYAVTVILLALILMLTKKYS
QAINPRRRKSMQVWVALMFISAVIQFIDKKILIVSFASVIGVLILFIMLENPMANIDRDTGFFNLNALFEYMKEAYGQGN
DVSIVCIRYGSNENDFFTREMEKSIFYEVVSFINKLPDNYVFRSSANEYLLVFENTDCAEKTIGILERRFDKPWGGDNMT
MLFGEIYYLRSTELVRRPSDILGLFQYAKRNRAEFTGRGVMLINNEVIEHIYDENSVENEIIEALRDNRVEVFYQPIYNT
KTHKFTSAEALVRIRSREGNIIPPGRFIAVAEKRGLILRLGERVFEIVCRFIVQHDIHAMGIEYIECNLSVVQCAYDHLA
QDFIAIMEKYHVDANDIVLEITESASITEKKILLDNMNALRKVGVRFALDDFGTGQSNLSYIVDMPIDIVKFDRGMTNAY
FDNGKGKPVMDAAMGMIQKLKLEIVSEGIEEKEQLAKLDELGIDYIQGYYFSKPRNAAEFISFIESNNT

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=430, Percent_Identity=26.7441860465116, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788502, Length=259, Percent_Identity=31.6602316602317, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081845, Length=264, Percent_Identity=29.9242424242424, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI226510982, Length=277, Percent_Identity=28.158844765343, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787541, Length=428, Percent_Identity=26.4018691588785, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=29.4820717131474, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87081743, Length=257, Percent_Identity=30.3501945525292, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=26.9709543568465, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786507, Length=288, Percent_Identity=28.4722222222222, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=30.3149606299213, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788849, Length=363, Percent_Identity=24.5179063360882, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=27.7992277992278, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72588; Mature: 72588

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVSQMCAIAVMFVIMYFYISQKKIILHTSKAFVEVWIAGLLSLFSDIFALVAIEKRSG
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YPHTATNIICKLYLWTVTWVAMVAFWYICVDIFRKKELERKWRKRLWIFGILTDILIMVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIKIYDSDNIVYTYGPAVIITYAVTVILLALILMLTKKYSQAINPRRRKSMQVWVALMFI
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SAVIQFIDKKILIVSFASVIGVLILFIMLENPMANIDRDTGFFNLNALFEYMKEAYGQGN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEHHHHHHHHHHHCCCCC
DVSIVCIRYGSNENDFFTREMEKSIFYEVVSFINKLPDNYVFRSSANEYLLVFENTDCAE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCHHH
KTIGILERRFDKPWGGDNMTMLFGEIYYLRSTELVRRPSDILGLFQYAKRNRAEFTGRGV
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEECHHHHHCCHHHHHHHHHHHCCCCCCCCCCE
MLINNEVIEHIYDENSVENEIIEALRDNRVEVFYQPIYNTKTHKFTSAEALVRIRSREGN
EEECHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCC
IIPPGRFIAVAEKRGLILRLGERVFEIVCRFIVQHDIHAMGIEYIECNLSVVQCAYDHLA
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHH
QDFIAIMEKYHVDANDIVLEITESASITEKKILLDNMNALRKVGVRFALDDFGTGQSNLS
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCE
YIVDMPIDIVKFDRGMTNAYFDNGKGKPVMDAAMGMIQKLKLEIVSEGIEEKEQLAKLDE
EEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGIDYIQGYYFSKPRNAAEFISFIESNNT
HCHHHHHCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNIVSQMCAIAVMFVIMYFYISQKKIILHTSKAFVEVWIAGLLSLFSDIFALVAIEKRSG
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YPHTATNIICKLYLWTVTWVAMVAFWYICVDIFRKKELERKWRKRLWIFGILTDILIMVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIKIYDSDNIVYTYGPAVIITYAVTVILLALILMLTKKYSQAINPRRRKSMQVWVALMFI
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SAVIQFIDKKILIVSFASVIGVLILFIMLENPMANIDRDTGFFNLNALFEYMKEAYGQGN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEHHHHHHHHHHHCCCCC
DVSIVCIRYGSNENDFFTREMEKSIFYEVVSFINKLPDNYVFRSSANEYLLVFENTDCAE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCHHH
KTIGILERRFDKPWGGDNMTMLFGEIYYLRSTELVRRPSDILGLFQYAKRNRAEFTGRGV
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEECHHHHHCCHHHHHHHHHHHCCCCCCCCCCE
MLINNEVIEHIYDENSVENEIIEALRDNRVEVFYQPIYNTKTHKFTSAEALVRIRSREGN
EEECHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCC
IIPPGRFIAVAEKRGLILRLGERVFEIVCRFIVQHDIHAMGIEYIECNLSVVQCAYDHLA
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHH
QDFIAIMEKYHVDANDIVLEITESASITEKKILLDNMNALRKVGVRFALDDFGTGQSNLS
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCE
YIVDMPIDIVKFDRGMTNAYFDNGKGKPVMDAAMGMIQKLKLEIVSEGIEEKEQLAKLDE
EEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGIDYIQGYYFSKPRNAAEFISFIESNNT
HCHHHHHCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]