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The map label for this gene is yrkP [H]

Identifier: 238925300

GI number: 238925300

Start: 2837871

End: 2838560

Strand: Reverse

Name: yrkP [H]

Synonym: EUBREC_2954

Alternate gene names: 238925300

Gene position: 2838560-2837871 (Counterclockwise)

Preceding gene: 238925301

Following gene: 238925299

Centisome position: 82.28

GC content: 47.97

Gene sequence:

>690_bases
ATGTATAAAGTATTAGTATGTGATGATGAAAAAGACATTGTATCGGCAATCAGCATTTATTTGACAAGCGATGGCTACGA
GGTAATCCCGGCGCGAAACGGGCTGGAGGCGCTCGATATAGTAAAACACAATGATGTGCATCTTGTCCTGATGGATATCA
TGATGCCTGTCATGGACGGAATAGAGGCGATGGTGGAAATCAGAAAAATCTCTAATGTGCCGGTCATACTGCTCACTGCC
AAAAGTGAGGACACTGACAAGGTACTCGGGCTCACGGTCGGAGCAGACGACTATGTGACGAAACCGTTTAACCCGGTAGA
GCTGCAGGCGAGGGTGAAGTCGCAGATCAGGAGGTACATGCTTCTTGGCGCAGGCAATACAAGCGCAGGAAAGCTGGTAA
TCGGCGGCATTGAGCTGGATGACAAATCAAAGACAGTGACAGTTGATGGCGAGGCAGCAAATCTTACACGTACAGAGTAC
GATATTTTGAAGCTTCTCATGGAGCATCCGGGCGAGGTGTATTCGCCAAATCAGATATATGCAAAGGTCTGGAAGGATGA
GCCGTATGGGACAGAAAACACGGTGGCGGTACATATCCGCCATCTCAGAGAAAAGGTTGAGATAAATCCGGCTGAGCCAA
GATACTTAAAGGTCATCTGGGGTCGCGGATACAAAATTGACGCTGAATAG

Upstream 100 bases:

>100_bases
ATTAAGATTATTTCTTAAACAAATCTTAATGTGTTACATAATTGGATTTTAATGTTACAATTGATACAATAAGACCAACA
TAAAACTTCCGGAGGCAATT

Downstream 100 bases:

>100_bases
GTGCATGCTTGATAAAGTTTGTCAAGTGAAGCACTATAAAATGGAAGGTGAATGATATGAAAAAAATATCAAGGAATCTG
TGGCTTAAGCTTGCGGCATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MYKVLVCDDEKDIVSAISIYLTSDGYEVIPARNGLEALDIVKHNDVHLVLMDIMMPVMDGIEAMVEIRKISNVPVILLTA
KSEDTDKVLGLTVGADDYVTKPFNPVELQARVKSQIRRYMLLGAGNTSAGKLVIGGIELDDKSKTVTVDGEAANLTRTEY
DILKLLMEHPGEVYSPNQIYAKVWKDEPYGTENTVAVHIRHLREKVEINPAEPRYLKVIWGRGYKIDAE

Sequences:

>Translated_229_residues
MYKVLVCDDEKDIVSAISIYLTSDGYEVIPARNGLEALDIVKHNDVHLVLMDIMMPVMDGIEAMVEIRKISNVPVILLTA
KSEDTDKVLGLTVGADDYVTKPFNPVELQARVKSQIRRYMLLGAGNTSAGKLVIGGIELDDKSKTVTVDGEAANLTRTEY
DILKLLMEHPGEVYSPNQIYAKVWKDEPYGTENTVAVHIRHLREKVEINPAEPRYLKVIWGRGYKIDAE
>Mature_229_residues
MYKVLVCDDEKDIVSAISIYLTSDGYEVIPARNGLEALDIVKHNDVHLVLMDIMMPVMDGIEAMVEIRKISNVPVILLTA
KSEDTDKVLGLTVGADDYVTKPFNPVELQARVKSQIRRYMLLGAGNTSAGKLVIGGIELDDKSKTVTVDGEAANLTRTEY
DILKLLMEHPGEVYSPNQIYAKVWKDEPYGTENTVAVHIRHLREKVEINPAEPRYLKVIWGRGYKIDAE

Specific function: Member of the two-component regulatory system yrkQ/yrkP [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=35.3982300884956, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=34.3612334801762, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=31.7180616740088, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=33.1877729257642, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.5991189427313, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=34.070796460177, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=209, Percent_Identity=34.4497607655502, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=34.3612334801762, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=32.3008849557522, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=32.7586206896552, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=31.1688311688312, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=27.4336283185841, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=25.4237288135593, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=40.6779661016949, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=36, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25614; Mature: 25614

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVLVCDDEKDIVSAISIYLTSDGYEVIPARNGLEALDIVKHNDVHLVLMDIMMPVMDG
CEEEEEECCCHHHHEEEEEEEECCCCEEEECCCCCCEEEEEECCCEEEEHHHHHHHHHHH
IEAMVEIRKISNVPVILLTAKSEDTDKVLGLTVGADDYVTKPFNPVELQARVKSQIRRYM
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEE
LLGAGNTSAGKLVIGGIELDDKSKTVTVDGEAANLTRTEYDILKLLMEHPGEVYSPNQIY
EEECCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
AKVWKDEPYGTENTVAVHIRHLREKVEINPAEPRYLKVIWGRGYKIDAE
EEEECCCCCCCCCEEEEEEHHHHHHHCCCCCCCEEEEEEECCCEEECCC
>Mature Secondary Structure
MYKVLVCDDEKDIVSAISIYLTSDGYEVIPARNGLEALDIVKHNDVHLVLMDIMMPVMDG
CEEEEEECCCHHHHEEEEEEEECCCCEEEECCCCCCEEEEEECCCEEEEHHHHHHHHHHH
IEAMVEIRKISNVPVILLTAKSEDTDKVLGLTVGADDYVTKPFNPVELQARVKSQIRRYM
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEE
LLGAGNTSAGKLVIGGIELDDKSKTVTVDGEAANLTRTEYDILKLLMEHPGEVYSPNQIY
EEECCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
AKVWKDEPYGTENTVAVHIRHLREKVEINPAEPRYLKVIWGRGYKIDAE
EEEECCCCCCCCCEEEEEEHHHHHHHCCCCCCCEEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]