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The map label for this gene is lrgA [H]

Identifier: 238925239

GI number: 238925239

Start: 2770688

End: 2771065

Strand: Reverse

Name: lrgA [H]

Synonym: EUBREC_2893

Alternate gene names: 238925239

Gene position: 2771065-2770688 (Counterclockwise)

Preceding gene: 238925240

Following gene: 238925238

Centisome position: 80.33

GC content: 43.39

Gene sequence:

>378_bases
ATGAAATTATTAAAGCAATTTCTCATCATACTTGCGATTTCGTTTGTAGGTGAGATACTCAAATATTTACTGCCATTGCC
TGTTCCGGCGAGCATATATGGCATGGTTATACTTTTCATAGGTCTGCTGACAGGCCTGATACCGCTTAACTCTGTAAGGA
GTGCAGGCAAATTCATGATAGAGATAATGCCTGTCATGTTTATCCCTGCGGGAGTGGGACTTATGTCATCCTGGGGCAAT
CTTAAGCCGGTGCTCGTACCGGTGATTGTAATCACGGTTGTGGCACTTCTTACTGTAATGATTGCTACAGGACATGTTTC
ACAGCTCGTAATCCGTATGCAGAAGCGCAAGAGGGCTGATGCTGGAGAAAATAAATAA

Upstream 100 bases:

>100_bases
AAGCGTGCTGCTTGCCATTGTATGTACAATGATGGTCAGGGAACACAGATAAACGGTTACAAATAGTCACGAAATATATA
TAACGGAGATACAATATAAA

Downstream 100 bases:

>100_bases
GATAGAGGATAATCATAATGGATAATTTGTTTCAGACATCGCTTTTTGCCGGTGTCACAGTAAGTCTGGTTGCATATCTG
CTAGGTATGCTTTTAAAGAA

Product: putative effector of murein hydrolase LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKLLKQFLIILAISFVGEILKYLLPLPVPASIYGMVILFIGLLTGLIPLNSVRSAGKFMIEIMPVMFIPAGVGLMSSWGN
LKPVLVPVIVITVVALLTVMIATGHVSQLVIRMQKRKRADAGENK

Sequences:

>Translated_125_residues
MKLLKQFLIILAISFVGEILKYLLPLPVPASIYGMVILFIGLLTGLIPLNSVRSAGKFMIEIMPVMFIPAGVGLMSSWGN
LKPVLVPVIVITVVALLTVMIATGHVSQLVIRMQKRKRADAGENK
>Mature_125_residues
MKLLKQFLIILAISFVGEILKYLLPLPVPASIYGMVILFIGLLTGLIPLNSVRSAGKFMIEIMPVMFIPAGVGLMSSWGN
LKPVLVPVIVITVVALLTVMIATGHVSQLVIRMQKRKRADAGENK

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in p

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788463, Length=109, Percent_Identity=34.8623853211009, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13597; Mature: 13597

Theoretical pI: Translated: 11.04; Mature: 11.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKQFLIILAISFVGEILKYLLPLPVPASIYGMVILFIGLLTGLIPLNSVRSAGKFMI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMPVMFIPAGVGLMSSWGNLKPVLVPVIVITVVALLTVMIATGHVSQLVIRMQKRKRAD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGENK
CCCCC
>Mature Secondary Structure
MKLLKQFLIILAISFVGEILKYLLPLPVPASIYGMVILFIGLLTGLIPLNSVRSAGKFMI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMPVMFIPAGVGLMSSWGNLKPVLVPVIVITVVALLTVMIATGHVSQLVIRMQKRKRAD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGENK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA