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The map label for this gene is cisA [H]

Identifier: 238925086

GI number: 238925086

Start: 2600505

End: 2602049

Strand: Direct

Name: cisA [H]

Synonym: EUBREC_2739

Alternate gene names: 238925086

Gene position: 2600505-2602049 (Clockwise)

Preceding gene: 238925085

Following gene: 238925088

Centisome position: 75.38

GC content: 48.09

Gene sequence:

>1545_bases
TTGGTAGCTCCATTCCAACAAGGAAAGGAGCCCAATATGGAATTTATCAGAGAAGATTGTATTTACGCAAGACAGTCAGT
AGACCGCAAGGACAGTATCAGCATTGAAAGTCAGATCGACTTTTGCAAGTATGAATTGAAAGGTGGTAGCTGCCGGGTAT
TCAAGGACAAAGGCTATTCCGGTAAAAATACGGACAGGCCGGAGTTTCAAAAGCTGCTGGGCGAGATCCGCAAGGGAAAG
GTCAGGCGGGTCATCGTGTATAAACTGGACCGTATAAGCCGCTCTATTCTGGACTTTGCAACGATGATGGAGCTGTTTCA
AGAGTATGATGTGGAGTTTGTATCATCCACAGAAAAGTTTGATACTTCGACCCCGATGGGCCGGGCCATGCTGAATATCT
GCATTGTATTCGCCCAGCTTGAACGTGAGACAATTCAGAAGCGTGTCACAGACGCCTACTATTCACGGTGCCTGAAAGGC
TTTCACATGAGCGGACAGGCACCATACGGTTATCAGTTAGAGCCTACTGTGGTAGAGGGTATCCGCACAAAGAAAATGGT
TGCCGACCCCGTAGCCGCCGACCATGTTCGGCTGATGTTTGAAATGTACGCTGAACCGGAAACCTCCTTCGGAGATATTA
CCCGATACTTCGAGGAACATGACATAAAAATTTATGGCAAATCCATGTTCCGTACATTTCTTTCCCAGCTTTTAAGAAAC
CCCGTTTACGCACAGGCCGATTTGGAGCTGTACGAATTTTTCAAAAGCCAGGGCGCAGCGATTATCAATGACGCTTCTGA
CTTTGCCGGAACAAACGGCTGCTATCTTTATCAGGGACGGGATGTGAAGGAGGACAAGGACAGGTGCTTAAAAGACCAGA
TACTTGTTATCGCTCCCCACGAAGCACTCATTTCCTCTGACACATGGCTGAAATGCCGGAAAAAGCTCATGGCAAATACC
ACCTTCCAGCAGGGGCGGAAACCGAAAAATACTTGGCTGGCCGGAAAAATCAAATGCGGGCATTGTGGGTATGCGCTGAA
AGCCACCCATGTACCAAACAGTACAGGCTATTTCCGCTGCACCAAACGGACGGAAAACAAAGGCTGTCCGGGCTGCGGGA
AAATCCGCAAAGAAGAATTTGAGCAATTCATTTTCTCGGCCATGCAGGAGAAGTTCAAAGACTTTCAGATACTCCACGGC
AGGGAGGAAAAAGTCAATCCGAAGCTGACCACCTATCAAGTGGAGCTGGCACAGGTGGAGGCAGAAATTGAAAAGCTGCT
GGATACGCTGACCGGAGCCAATGCGACCTTGCTTGCCTATGCCAACAAAAAAATTGAAGAACTGGACACCCGACGCCAGA
CCATTTCAAAGGCAATCGCCGAATTGAGCGTTGAAACCATATCGCCCCAGCAGATAAAGAAGTTGTCCTATTATCTCGAC
AACTGGGAGAGCATAGATTTTGACGACAAAAGAAAAGCCGCCGATGGTTTGATCTCTACGATCAAGGCCACCAGCGACCG
TGTTCAGATAGAGTGGAAAATCTGA

Upstream 100 bases:

>100_bases
GTTGTCTTTATGAGGTGTTCCGCAAATATGGGGACAGATTTCCCTAATTATTCGCAACATTGTTGTCCGGGGCTGCTGAT
GGTATAATATAGTTGTAAGG

Downstream 100 bases:

>100_bases
TATTTCCGCTCTATCGCCCCTCATTTCTATTTTATCTCGTTTGTACCCCTTGTACACCGATGCTTGTAGTTCTTTATAAA
AGGTAATTTTATTATATGTT

Product: site-specific recombinases, DNA invertase Pin-like protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MVAPFQQGKEPNMEFIREDCIYARQSVDRKDSISIESQIDFCKYELKGGSCRVFKDKGYSGKNTDRPEFQKLLGEIRKGK
VRRVIVYKLDRISRSILDFATMMELFQEYDVEFVSSTEKFDTSTPMGRAMLNICIVFAQLERETIQKRVTDAYYSRCLKG
FHMSGQAPYGYQLEPTVVEGIRTKKMVADPVAADHVRLMFEMYAEPETSFGDITRYFEEHDIKIYGKSMFRTFLSQLLRN
PVYAQADLELYEFFKSQGAAIINDASDFAGTNGCYLYQGRDVKEDKDRCLKDQILVIAPHEALISSDTWLKCRKKLMANT
TFQQGRKPKNTWLAGKIKCGHCGYALKATHVPNSTGYFRCTKRTENKGCPGCGKIRKEEFEQFIFSAMQEKFKDFQILHG
REEKVNPKLTTYQVELAQVEAEIEKLLDTLTGANATLLAYANKKIEELDTRRQTISKAIAELSVETISPQQIKKLSYYLD
NWESIDFDDKRKAADGLISTIKATSDRVQIEWKI

Sequences:

>Translated_514_residues
MVAPFQQGKEPNMEFIREDCIYARQSVDRKDSISIESQIDFCKYELKGGSCRVFKDKGYSGKNTDRPEFQKLLGEIRKGK
VRRVIVYKLDRISRSILDFATMMELFQEYDVEFVSSTEKFDTSTPMGRAMLNICIVFAQLERETIQKRVTDAYYSRCLKG
FHMSGQAPYGYQLEPTVVEGIRTKKMVADPVAADHVRLMFEMYAEPETSFGDITRYFEEHDIKIYGKSMFRTFLSQLLRN
PVYAQADLELYEFFKSQGAAIINDASDFAGTNGCYLYQGRDVKEDKDRCLKDQILVIAPHEALISSDTWLKCRKKLMANT
TFQQGRKPKNTWLAGKIKCGHCGYALKATHVPNSTGYFRCTKRTENKGCPGCGKIRKEEFEQFIFSAMQEKFKDFQILHG
REEKVNPKLTTYQVELAQVEAEIEKLLDTLTGANATLLAYANKKIEELDTRRQTISKAIAELSVETISPQQIKKLSYYLD
NWESIDFDDKRKAADGLISTIKATSDRVQIEWKI
>Mature_514_residues
MVAPFQQGKEPNMEFIREDCIYARQSVDRKDSISIESQIDFCKYELKGGSCRVFKDKGYSGKNTDRPEFQKLLGEIRKGK
VRRVIVYKLDRISRSILDFATMMELFQEYDVEFVSSTEKFDTSTPMGRAMLNICIVFAQLERETIQKRVTDAYYSRCLKG
FHMSGQAPYGYQLEPTVVEGIRTKKMVADPVAADHVRLMFEMYAEPETSFGDITRYFEEHDIKIYGKSMFRTFLSQLLRN
PVYAQADLELYEFFKSQGAAIINDASDFAGTNGCYLYQGRDVKEDKDRCLKDQILVIAPHEALISSDTWLKCRKKLMANT
TFQQGRKPKNTWLAGKIKCGHCGYALKATHVPNSTGYFRCTKRTENKGCPGCGKIRKEEFEQFIFSAMQEKFKDFQILHG
REEKVNPKLTTYQVELAQVEAEIEKLLDTLTGANATLLAYANKKIEELDTRRQTISKAIAELSVETISPQQIKKLSYYLD
NWESIDFDDKRKAADGLISTIKATSDRVQIEWKI

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=134, Percent_Identity=32.089552238806, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 59131; Mature: 59131

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPFQQGKEPNMEFIREDCIYARQSVDRKDSISIESQIDFCKYELKGGSCRVFKDKGYS
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCCEEEEEECCCCC
GKNTDRPEFQKLLGEIRKGKVRRVIVYKLDRISRSILDFATMMELFQEYDVEFVSSTEKF
CCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHC
DTSTPMGRAMLNICIVFAQLERETIQKRVTDAYYSRCLKGFHMSGQAPYGYQLEPTVVEG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
IRTKKMVADPVAADHVRLMFEMYAEPETSFGDITRYFEEHDIKIYGKSMFRTFLSQLLRN
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCC
PVYAQADLELYEFFKSQGAAIINDASDFAGTNGCYLYQGRDVKEDKDRCLKDQILVIAPH
CCCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCEEEECCCCCCHHHHHHHHCCEEEEECC
EALISSDTWLKCRKKLMANTTFQQGRKPKNTWLAGKIKCGHCGYALKATHVPNSTGYFRC
HHHHCCCHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEEE
TKRTENKGCPGCGKIRKEEFEQFIFSAMQEKFKDFQILHGREEKVNPKLTTYQVELAQVE
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHH
AEIEKLLDTLTGANATLLAYANKKIEELDTRRQTISKAIAELSVETISPQQIKKLSYYLD
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NWESIDFDDKRKAADGLISTIKATSDRVQIEWKI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MVAPFQQGKEPNMEFIREDCIYARQSVDRKDSISIESQIDFCKYELKGGSCRVFKDKGYS
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEEEEECCCEEEEEECCCCC
GKNTDRPEFQKLLGEIRKGKVRRVIVYKLDRISRSILDFATMMELFQEYDVEFVSSTEKF
CCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHC
DTSTPMGRAMLNICIVFAQLERETIQKRVTDAYYSRCLKGFHMSGQAPYGYQLEPTVVEG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
IRTKKMVADPVAADHVRLMFEMYAEPETSFGDITRYFEEHDIKIYGKSMFRTFLSQLLRN
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCC
PVYAQADLELYEFFKSQGAAIINDASDFAGTNGCYLYQGRDVKEDKDRCLKDQILVIAPH
CCCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCEEEECCCCCCHHHHHHHHCCEEEEECC
EALISSDTWLKCRKKLMANTTFQQGRKPKNTWLAGKIKCGHCGYALKATHVPNSTGYFRC
HHHHCCCHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEEE
TKRTENKGCPGCGKIRKEEFEQFIFSAMQEKFKDFQILHGREEKVNPKLTTYQVELAQVE
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHH
AEIEKLLDTLTGANATLLAYANKKIEELDTRRQTISKAIAELSVETISPQQIKKLSYYLD
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
NWESIDFDDKRKAADGLISTIKATSDRVQIEWKI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]