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The map label for this gene is 238924560

Identifier: 238924560

GI number: 238924560

Start: 2054647

End: 2056008

Strand: Direct

Name: 238924560

Synonym: EUBREC_2202

Alternate gene names: NA

Gene position: 2054647-2056008 (Clockwise)

Preceding gene: 238924559

Following gene: 238924562

Centisome position: 59.56

GC content: 44.57

Gene sequence:

>1362_bases
ATGAAAAAAATAGATTTTGATAATGATTCAATAAAGAAAAATATATTGCAGGCTGCTCTGCCCATGCTGGCAGCCCAGAT
TCTAAGCCTGTTGTACAATATAGTAGACCGCATATACATTGCCCGCATACCGGATATGGGAACCACTGCACTCGGTGCTG
TGGGGCTTTGCTTTCCTATTATAATGCTGACAATCGCTTTCTCCAATCTCTTTGGAAGCGGTGGTGCTCCGCTTTTTTCA
ATAAAAAGAGGCATGAGTGATGACAGAGCCGCCAATACTATAATGAATACGAGCTTTACAATGGTCTGCACATTCGCAGT
CGTTTTTACAGCTTTGTGCATGATTTTTGCAAAGCCTCTTTTAATCGTGTTTGGCGCATCTGAAAATGCTCTCAAATACG
CTCTGCCATACCTGCTCATTTATTTGATAGGAACACTCCCATCCATGATTTCAACCGGCATGAATCCCTTTATCAACGCT
CAGGGCTACTCCACTACCGGCATGCTGTCTGTTGCAATCGGAGCCGTTGCCAATCTGGTTTTAGACCCGCTTTTTATATT
TGGATTTAATTTCGGTATCAAAGGAGCAGCTATTGCTACGGTCATCTCACAAATACTGTCTGCTCTCTATGTGCTTCACT
TTCTTAGGAAAAAGGCTGAGCTTAAGGTGCGCCTTATGACACTCTCTGAATTCAGTGAAAACACGCGCTATGCAAAGGAC
ATCATAAGCCTTGGAACCTCAGGCTGTGTCATGCAGCTCACAAACAGCCTGGTATCTATATGCTGCAACAATGTGCTTTC
AGTGACCGGTGGCGATTTGTACATATCGGTAATGACCATCGTATCAAGCATCAGGCAGATGGTCGAGACTCCAATTTATG
CAATTGTGGAGGGTTCATCTCCTGTTTTAAGCTACAACTATGGCGCCAAAAGGCCGGCCCGGGTGAGAAAATCTATTTTC
ACTATGGGACTGCTCGTGCTTCTATATACAGCTGTCATGTGGAGTGTGATTATACTTGCCCCTCATGCCCTGATTGCAAT
TTTCAGTTCCGATTCCACCCTTATGGATGATGCGGTGAAGGCTTTGAATATCTACTTTGCGGCATTCATATTTATGGATC
TGCAGTACATCGGACAGACCACCTTTAAATCACTGAACAAAAAGAAGCGGGCTATATTTTTCTCCCTGCTTCGCAAGGTG
TTCATCGTTGTACCGCTGACATATATTCTGCCTTACTCCTTTGGTATGGGAACCGACGGTGTGTTTATGGCAGAGCCTGT
ATCAAACGTGATTGGCGGAAGCATCTGCTTTGTAACCATGCTTGGCACTGTGCTACCTGAGCTTCGCAGAATGGAGCAGT
AA

Upstream 100 bases:

>100_bases
AGTTTGTCATAAATAAAATCTATATCAAAACTTGCTGAGCATTTGATTTTTTTATATGAGGTGATATAATGGGCGAAGCA
AATCAAAAAGAGGTTTCACA

Downstream 100 bases:

>100_bases
TTACAGCATCTCATCAATGCAGATGCCGTAGCCTCCGGTCGGATCATCGACAAACACATGGGTGACTGCTCCTATTATTT
TACCATCCTGTATGATAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKKIDFDNDSIKKNILQAALPMLAAQILSLLYNIVDRIYIARIPDMGTTALGAVGLCFPIIMLTIAFSNLFGSGGAPLFS
IKRGMSDDRAANTIMNTSFTMVCTFAVVFTALCMIFAKPLLIVFGASENALKYALPYLLIYLIGTLPSMISTGMNPFINA
QGYSTTGMLSVAIGAVANLVLDPLFIFGFNFGIKGAAIATVISQILSALYVLHFLRKKAELKVRLMTLSEFSENTRYAKD
IISLGTSGCVMQLTNSLVSICCNNVLSVTGGDLYISVMTIVSSIRQMVETPIYAIVEGSSPVLSYNYGAKRPARVRKSIF
TMGLLVLLYTAVMWSVIILAPHALIAIFSSDSTLMDDAVKALNIYFAAFIFMDLQYIGQTTFKSLNKKKRAIFFSLLRKV
FIVVPLTYILPYSFGMGTDGVFMAEPVSNVIGGSICFVTMLGTVLPELRRMEQ

Sequences:

>Translated_453_residues
MKKIDFDNDSIKKNILQAALPMLAAQILSLLYNIVDRIYIARIPDMGTTALGAVGLCFPIIMLTIAFSNLFGSGGAPLFS
IKRGMSDDRAANTIMNTSFTMVCTFAVVFTALCMIFAKPLLIVFGASENALKYALPYLLIYLIGTLPSMISTGMNPFINA
QGYSTTGMLSVAIGAVANLVLDPLFIFGFNFGIKGAAIATVISQILSALYVLHFLRKKAELKVRLMTLSEFSENTRYAKD
IISLGTSGCVMQLTNSLVSICCNNVLSVTGGDLYISVMTIVSSIRQMVETPIYAIVEGSSPVLSYNYGAKRPARVRKSIF
TMGLLVLLYTAVMWSVIILAPHALIAIFSSDSTLMDDAVKALNIYFAAFIFMDLQYIGQTTFKSLNKKKRAIFFSLLRKV
FIVVPLTYILPYSFGMGTDGVFMAEPVSNVIGGSICFVTMLGTVLPELRRMEQ
>Mature_453_residues
MKKIDFDNDSIKKNILQAALPMLAAQILSLLYNIVDRIYIARIPDMGTTALGAVGLCFPIIMLTIAFSNLFGSGGAPLFS
IKRGMSDDRAANTIMNTSFTMVCTFAVVFTALCMIFAKPLLIVFGASENALKYALPYLLIYLIGTLPSMISTGMNPFINA
QGYSTTGMLSVAIGAVANLVLDPLFIFGFNFGIKGAAIATVISQILSALYVLHFLRKKAELKVRLMTLSEFSENTRYAKD
IISLGTSGCVMQLTNSLVSICCNNVLSVTGGDLYISVMTIVSSIRQMVETPIYAIVEGSSPVLSYNYGAKRPARVRKSIF
TMGLLVLLYTAVMWSVIILAPHALIAIFSSDSTLMDDAVKALNIYFAAFIFMDLQYIGQTTFKSLNKKKRAIFFSLLRKV
FIVVPLTYILPYSFGMGTDGVFMAEPVSNVIGGSICFVTMLGTVLPELRRMEQ

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49423; Mature: 49423

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIDFDNDSIKKNILQAALPMLAAQILSLLYNIVDRIYIARIPDMGTTALGAVGLCFPI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IMLTIAFSNLFGSGGAPLFSIKRGMSDDRAANTIMNTSFTMVCTFAVVFTALCMIFAKPL
HHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LIVFGASENALKYALPYLLIYLIGTLPSMISTGMNPFINAQGYSTTGMLSVAIGAVANLV
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDPLFIFGFNFGIKGAAIATVISQILSALYVLHFLRKKAELKVRLMTLSEFSENTRYAKD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCHHHHHH
IISLGTSGCVMQLTNSLVSICCNNVLSVTGGDLYISVMTIVSSIRQMVETPIYAIVEGSS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PVLSYNYGAKRPARVRKSIFTMGLLVLLYTAVMWSVIILAPHALIAIFSSDSTLMDDAVK
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
ALNIYFAAFIFMDLQYIGQTTFKSLNKKKRAIFFSLLRKVFIVVPLTYILPYSFGMGTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VFMAEPVSNVIGGSICFVTMLGTVLPELRRMEQ
CEECCHHHHHHCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIDFDNDSIKKNILQAALPMLAAQILSLLYNIVDRIYIARIPDMGTTALGAVGLCFPI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
IMLTIAFSNLFGSGGAPLFSIKRGMSDDRAANTIMNTSFTMVCTFAVVFTALCMIFAKPL
HHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LIVFGASENALKYALPYLLIYLIGTLPSMISTGMNPFINAQGYSTTGMLSVAIGAVANLV
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDPLFIFGFNFGIKGAAIATVISQILSALYVLHFLRKKAELKVRLMTLSEFSENTRYAKD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHCCHHHHHH
IISLGTSGCVMQLTNSLVSICCNNVLSVTGGDLYISVMTIVSSIRQMVETPIYAIVEGSS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PVLSYNYGAKRPARVRKSIFTMGLLVLLYTAVMWSVIILAPHALIAIFSSDSTLMDDAVK
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
ALNIYFAAFIFMDLQYIGQTTFKSLNKKKRAIFFSLLRKVFIVVPLTYILPYSFGMGTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VFMAEPVSNVIGGSICFVTMLGTVLPELRRMEQ
CEECCHHHHHHCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]