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The map label for this gene is argD [H]

Identifier: 238921459

GI number: 238921459

Start: 3496684

End: 3497898

Strand: Reverse

Name: argD [H]

Synonym: NT01EI_3611

Alternate gene names: 238921459

Gene position: 3497898-3496684 (Counterclockwise)

Preceding gene: 238921461

Following gene: 238921457

Centisome position: 91.75

GC content: 62.14

Gene sequence:

>1215_bases
ATGACGCAGAAAAGTACAGTAGAGAGGGGCGATTTTGAAAAGGTTATGTTGCCGGTTTATGCACCCGCGGAGTTTGTGCC
GGTGCGCGGTCAAGGCAGCCGGGTGTGGGATCAGCAGGGGCGTGATTATATTGACTTTGCCGGTGGCATTGCGGTTACGG
CGCTGGGGCACTGCCATCCGGCATTGGTGGCTGCGCTACAGGAGCAGGGGAGCCGTCTGTGGCATACCAGTAATGTCTTT
ACCAATGAGCCCGCGCTGCGACTGGCGCAAAAGCTGATCGATGCCACCTTTGCTGAGCGGGTGTTTTTTGCCAACTCCGG
TGCAGAGGCCAATGAGGCGGCGCTAAAGCTGGCCCGCTACCACGCTGCGACGCGTATCAGCCCTCATAAAAGCCAGATTA
TCGCCTTCAAGCAGGGATTTCATGGCCGCACCCTGTTTACGGTATCGGTGGGGGGGCAGGCGAAATACGCGGACGGCTTT
GGGCCAAAGCCGGCGGATATTGTGCACGTCCCGTTTAACGACGTGGCGGCGGTTGAGGCGATCATCGGTGAACAGACCTG
TGCGGTGATCGTCGAGCCTGTTCAGGGCGAGGGTGGGGTATTACCGGCCAGCGCAGATTTTCTGCAGGGGCTGCGCACGC
TGTGCGATCGTCACCGGGCGCTGCTGATTTTTGATGAGGTGCAAAGTGGGATGGGACGCAGCGGTAGGCTGTTTAGTTAC
ATGCACTATGGCGTGACGCCGGATATTCTGACCAGCGCCAAGGCACTGGGCGGCGGGTTTCCGATCAGCGCCATGCTGAC
CACCGAAGCGATCGCCTCAGCGATGACGGTGGGCTGCCACGGCACGACCTATGGCGGCAATCCGCTGGCCTGTGCGGTGG
CGGAGGCGGCGTTCGATATCATCAGCCAGCCGCAGGTCCTTGCCGGGGTGACGATGCGCCGGCAGGTCATGGTTAGCCAT
TTGCAGGCCCTTAACCGGCGTCACGGGACGTTTAGCGACATCCGCGGACAGGGACTGCTGCTAGGGGCGGCTTTGTCGCC
CGCCTACCGGGGACGGGCCCGAGACATTCTGCATGCGGCGGCGGAGCAGGGGGTGATGTTGCTGAACGCTGGCGCCGATA
CGCTGCGCTTTACGCCGTCTCTGGTGATCGAGACGGCGGAGATCGAGGAGGGGATGGCCCGCCTGGGGCGGGCGCTGGAT
ACGCTGGCGGCCTAG

Upstream 100 bases:

>100_bases
TCGGTGTTGAAAACATGGTTGCCATTTATTGAGTTATTATTCATATTTTATGATTATAAAATCATTTTTGCTTGACCGGT
GCGAATGGGGAGAACGTGGG

Downstream 100 bases:

>100_bases
GCGGCGCTCAGGCGTTATCGCTCTCCGTGAAGGCGCGGGACATCGCTTCGAGCTGCTCCTGCGCATCGAGCCAGCACAGC
TCCGCCTCTTCCAGACCGAG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTQKSTVERGDFEKVMLPVYAPAEFVPVRGQGSRVWDQQGRDYIDFAGGIAVTALGHCHPALVAALQEQGSRLWHTSNVF
TNEPALRLAQKLIDATFAERVFFANSGAEANEAALKLARYHAATRISPHKSQIIAFKQGFHGRTLFTVSVGGQAKYADGF
GPKPADIVHVPFNDVAAVEAIIGEQTCAVIVEPVQGEGGVLPASADFLQGLRTLCDRHRALLIFDEVQSGMGRSGRLFSY
MHYGVTPDILTSAKALGGGFPISAMLTTEAIASAMTVGCHGTTYGGNPLACAVAEAAFDIISQPQVLAGVTMRRQVMVSH
LQALNRRHGTFSDIRGQGLLLGAALSPAYRGRARDILHAAAEQGVMLLNAGADTLRFTPSLVIETAEIEEGMARLGRALD
TLAA

Sequences:

>Translated_404_residues
MTQKSTVERGDFEKVMLPVYAPAEFVPVRGQGSRVWDQQGRDYIDFAGGIAVTALGHCHPALVAALQEQGSRLWHTSNVF
TNEPALRLAQKLIDATFAERVFFANSGAEANEAALKLARYHAATRISPHKSQIIAFKQGFHGRTLFTVSVGGQAKYADGF
GPKPADIVHVPFNDVAAVEAIIGEQTCAVIVEPVQGEGGVLPASADFLQGLRTLCDRHRALLIFDEVQSGMGRSGRLFSY
MHYGVTPDILTSAKALGGGFPISAMLTTEAIASAMTVGCHGTTYGGNPLACAVAEAAFDIISQPQVLAGVTMRRQVMVSH
LQALNRRHGTFSDIRGQGLLLGAALSPAYRGRARDILHAAAEQGVMLLNAGADTLRFTPSLVIETAEIEEGMARLGRALD
TLAA
>Mature_403_residues
TQKSTVERGDFEKVMLPVYAPAEFVPVRGQGSRVWDQQGRDYIDFAGGIAVTALGHCHPALVAALQEQGSRLWHTSNVFT
NEPALRLAQKLIDATFAERVFFANSGAEANEAALKLARYHAATRISPHKSQIIAFKQGFHGRTLFTVSVGGQAKYADGFG
PKPADIVHVPFNDVAAVEAIIGEQTCAVIVEPVQGEGGVLPASADFLQGLRTLCDRHRALLIFDEVQSGMGRSGRLFSYM
HYGVTPDILTSAKALGGGFPISAMLTTEAIASAMTVGCHGTTYGGNPLACAVAEAAFDIISQPQVLAGVTMRRQVMVSHL
QALNRRHGTFSDIRGQGLLLGAALSPAYRGRARDILHAAAEQGVMLLNAGADTLRFTPSLVIETAEIEEGMARLGRALDT
LAA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=33.6760925449871, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI284507298, Length=304, Percent_Identity=34.2105263157895, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI13994255, Length=414, Percent_Identity=29.951690821256, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI37574042, Length=412, Percent_Identity=29.126213592233, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=29.0909090909091, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=28.1553398058252, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=25.8454106280193, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=69.5214105793451, Blast_Score=599, Evalue=1e-173,
Organism=Escherichia coli, GI1788044, Length=394, Percent_Identity=61.1675126903553, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=35.9102244389027, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=35.2357320099256, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI145693181, Length=376, Percent_Identity=34.8404255319149, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786991, Length=298, Percent_Identity=33.2214765100671, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786349, Length=293, Percent_Identity=32.4232081911263, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=34.9333333333333, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=422, Percent_Identity=28.1990521327014, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=273, Percent_Identity=34.7985347985348, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.2051282051282, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=26.027397260274, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=30.379746835443, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=39.3034825870647, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=33.3333333333333, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=312, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.5978835978836, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=28.780487804878, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=28.1990521327014, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356575, Length=361, Percent_Identity=30.1939058171745, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=23.4883720930233, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=23.4883720930233, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=23.4883720930233, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43037; Mature: 42906

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKSTVERGDFEKVMLPVYAPAEFVPVRGQGSRVWDQQGRDYIDFAGGIAVTALGHCHP
CCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCHHHCCCCEEHHCCCHHHHHHHCHHH
ALVAALQEQGSRLWHTSNVFTNEPALRLAQKLIDATFAERVFFANSGAEANEAALKLARY
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
HAATRISPHKSQIIAFKQGFHGRTLFTVSVGGQAKYADGFGPKPADIVHVPFNDVAAVEA
HHHHCCCCCHHHEEEEECCCCCCEEEEEEECCCEEECCCCCCCCCCEEECCCCHHHHHHH
IIGEQTCAVIVEPVQGEGGVLPASADFLQGLRTLCDRHRALLIFDEVQSGMGRSGRLFSY
HHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTSAKALGGGFPISAMLTTEAIASAMTVGCHGTTYGGNPLACAVAEAAFDI
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ISQPQVLAGVTMRRQVMVSHLQALNRRHGTFSDIRGQGLLLGAALSPAYRGRARDILHAA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHCCHHHHHHHHH
AEQGVMLLNAGADTLRFTPSLVIETAEIEEGMARLGRALDTLAA
HHCCEEEEECCCCCEEECHHHEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQKSTVERGDFEKVMLPVYAPAEFVPVRGQGSRVWDQQGRDYIDFAGGIAVTALGHCHP
CCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCHHHCCCCEEHHCCCHHHHHHHCHHH
ALVAALQEQGSRLWHTSNVFTNEPALRLAQKLIDATFAERVFFANSGAEANEAALKLARY
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
HAATRISPHKSQIIAFKQGFHGRTLFTVSVGGQAKYADGFGPKPADIVHVPFNDVAAVEA
HHHHCCCCCHHHEEEEECCCCCCEEEEEEECCCEEECCCCCCCCCCEEECCCCHHHHHHH
IIGEQTCAVIVEPVQGEGGVLPASADFLQGLRTLCDRHRALLIFDEVQSGMGRSGRLFSY
HHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEE
MHYGVTPDILTSAKALGGGFPISAMLTTEAIASAMTVGCHGTTYGGNPLACAVAEAAFDI
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ISQPQVLAGVTMRRQVMVSHLQALNRRHGTFSDIRGQGLLLGAALSPAYRGRARDILHAA
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHCCHHHHHHHHH
AEQGVMLLNAGADTLRFTPSLVIETAEIEEGMARLGRALDTLAA
HHCCEEEEECCCCCEEECHHHEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]