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The map label for this gene is metA

Identifier: 238921399

GI number: 238921399

Start: 3445595

End: 3446524

Strand: Reverse

Name: metA

Synonym: NT01EI_3543

Alternate gene names: 238921399

Gene position: 3446524-3445595 (Counterclockwise)

Preceding gene: 238921400

Following gene: 238921398

Centisome position: 90.41

GC content: 53.66

Gene sequence:

>930_bases
ATGCCAATCAGGATCCCTGACGCGTTGCCCGCCGTTAATTTTTTACGTAATGAAAATGTCTTTGTCATGACCGATTCCCG
GGCAGCGGTGCAGGAGATCCGTCCGCTGAAGGTGCTGTTGCTGAATCTGATGCCAAAGAAAATCGAGACTGAAAATCAGT
TTCTGCGTCTGTTGTCGAACTCGCCACTGCAGATCGATATTCAGCTGTTGCGCATCGATCGGCGTGAGTCAAAAAATACG
CCGATGGAGCATCTGAATAACTTTTACTGTCATTTTGAGGATATTCAGCAAGAAAATTTTGATGGTCTTGTCGTGACCGG
CGCGCCGCTGGGACAAGTAGATTTTGGCGATGTTGCCTACTGGTCGCAGATCGTGCAGGTTATTGAGTGGGCGCGGGCGC
ACGTGACATCGACCCTGTTCGTCTGCTGGGCCGCGCAGGCGGCGCTTAATATTCTGTATGGACTGCCGAAGATGACGCGG
GCGCAGAAGCTATCCGGGGTTTATGAGCATCAGACGCTCAATCCGCTGGCGCTGTTGACCCGTGGCTTTGACGAAGGCTT
TTTGGCGCCGCATTCGCGCTATGCCGACTTTCCGCCGCAGGCGATCCGTGAGCATACTGATCTGCAGATCTTTGCCGAGT
CTGCGCAGGCCGGCGCCTACCTGTTTGCCAGCGTCGATAAGCGAACGGTGTTTGTTACGGGCCATCCGGAATATGATGCC
CATACGCTGGGTGCTGAATATTGGCGCGATCTGCACGCTGGCCTGACACCGGCACTGCCGTTTAACTATTTTCCCCAGGA
TAATTCGGACGGTACGCCGTTGGCGACCTGGCGCAGCCACGGTCACCTGTTGTTCAGTAACTGGCTAAACTACTGTGTTT
ACCAGATAACTCCTTACGATCTGCGTCAGATGAATCCCACCTTGGAGTAA

Upstream 100 bases:

>100_bases
TCAACGCTCTGTGCTGTACAAACGGCGTAAAACCGATTAATTTGGCTATCCAGATGTCTAAATGGACAAGGTTTGCCTTT
GATCGTCCAGGAGAGCGTTT

Downstream 100 bases:

>100_bases
GATCTACGCGCCATTTCCCCGGGCTAGCAGTAGACGGGGGGAATGACAAATAACCCTCACATTTCTCTGCCGTAATGCGT
ATAATCGCCGCCCTGATCCT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDRRESKNT
PMEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAYWSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTR
AQKLSGVYEHQTLNPLALLTRGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDA
HTLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYDLRQMNPTLE

Sequences:

>Translated_309_residues
MPIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDRRESKNT
PMEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAYWSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTR
AQKLSGVYEHQTLNPLALLTRGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDA
HTLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYDLRQMNPTLE
>Mature_308_residues
PIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDRRESKNTP
MEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAYWSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTRA
QKLSGVYEHQTLNPLALLTRGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDAH
TLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYDLRQMNPTLE

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=309, Percent_Identity=76.0517799352751, Blast_Score=503, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_EDWI9 (C5BF07)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934914.1
- ProteinModelPortal:   C5BF07
- SMR:   C5BF07
- GeneID:   7962541
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3543
- OMA:   QAGLYYH
- ProtClustDB:   PRK05368
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 35303; Mature: 35171

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSN
CCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCC
SPLQIDIQLLRIDRRESKNTPMEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAY
CCCEEEEEEEEEECCCCCCCCHHHHHCCEEEHHHHHCCCCCEEEEECCCCCCCCCCHHHH
WSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTRAQKLSGVYEHQTLNPLALLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
RGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDA
CCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEEECCCEEEEEECCCCCCC
HTLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHEEEECCCHH
LRQMNPTLE
HHHCCCCCC
>Mature Secondary Structure 
PIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSN
CCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHCC
SPLQIDIQLLRIDRRESKNTPMEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAY
CCCEEEEEEEEEECCCCCCCCHHHHHCCEEEHHHHHCCCCCEEEEECCCCCCCCCCHHHH
WSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTRAQKLSGVYEHQTLNPLALLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
RGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDA
CCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEEECCCEEEEEECCCCCCC
HTLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHEEEECCCHH
LRQMNPTLE
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA