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The map label for this gene is csrD [H]

Identifier: 238921348

GI number: 238921348

Start: 3390034

End: 3391926

Strand: Reverse

Name: csrD [H]

Synonym: NT01EI_3492

Alternate gene names: 238921348

Gene position: 3391926-3390034 (Counterclockwise)

Preceding gene: 238921349

Following gene: 238921347

Centisome position: 88.97

GC content: 59.69

Gene sequence:

>1893_bases
ATGCGTATTACAACAAAATTCTTTGCCTTTACTACCTTACTGGTTGTGTTAGGGATGTTTCTGATGCTGCTGGGCAGCAC
CTATAGCTTTTACAGCCAGACCCATCAGCGTGCAGAGATCCAGCTTAATATCCTGACGGCGATGATCGACCAACAGCTGT
TGACCGAGTCCCGCGACAGCGTAAAGCGTTGGCTTCCGGTGATGATGCGATCGGCCGGTGCCGTCGAGCTGTCGGTTTAT
CATGACGGTAGCCAGGTCTATTACCACCATCTGCCCGCGCTGTACAACCCGTGGCGCACCGACGATAACCTGCGTAGCTT
TGAGTCGCCGCTGCTGCAGCATCCGGGCTATCGTCTGAAGCTGGTCTACATTGAACCAACGGACAGCTATAGCCACTCGC
TGGAGCGCATGTTCCCGCTCTCGCTTTCCATTGGCGTTATGGTGATCATGCTGTTTATCGCCTATCGCTGGCTGCGTAGA
CAGACCCTGGGGATCGAGCGGCTGGATCGCCGGTCGCGCCGTATTCTGTCCGGCGATCGCGATCTGCGCGTGGGCGGCGT
CGGCGAGTTTCCCGCCAGCGTCAGCAGCGCGCTCGACTGCCTGCTCTCCGAGCTGTCCGATGCGTGCGAAGAGCGCAGCC
GTATCGACTCGCTGATCCGCGCTTTTGCTGCACAGGACTCGCGCACCGGGTTGAACAACCGCCTGTTTTTCGATAATCAA
CTGACCACCCTGCTAGAGGATGAGGGAGCCCACGGCGTGGTGATGATCCTGCGTCTGCCGGATCTGGAGACGCTGGTCAG
CCAGCCTGGACGGCGCCAGCGCGAAGAGTTTCGCTATGCGCTGACCAATATGCTGTCGACCTATGTCATGCGCTACCCTT
CAGGCCTGTTGGCCCACTATTTTCAGAATAACTTTGCCGTGCTGCTGCCGCATCGTTCGCTGAAAGAGGCGGAGGGCTTT
GCCGCTCAGCTGCTGGCTTCGCTGGCGGCTATTCCCTCGGCACCGGGGGTGAGCACCGATGAGGTGTTGCATATCGGGAT
CACTCTGTACCGCGCTGGCGAGCAGGTGGAGTCGGTGATGGATCGTGCCGAGCAGGCGGCGCGCAGCGCGACCCTGCAGG
GCGGCAACGGATGGTTTGTCGATAAGACGCCGCAGCCGGAGATGGTGCGCGGTAGCGTGCGCTGGCGTACCCTGCTGGAG
CAGACCCTGGCGCGCGGCGGGGCGAGGTTGTTCCATAAGCCCGCGGTAACGGTGGATGGGCGGGTGCATCACCATTACAT
CCTGCCGTATATTTATGACGGTAATCAGCCAATCCTCAGCGCTGAATTTATGCCGCTGGTGCAACAGTTGGGGCTGGCGG
AGCGCTTCGATCGCCAGATGGTCAGTCAGATTATTCCGTTGTTGCGCCGTCTGCCGGGACAAAGGCTGGCCTTTCCGCTG
ACGGTTGACTCATTATTACAGCGTAGCTTTCAGCGCTGGCTGCGCGACACCCTGCTGCAGAGTGAGCGCCTGCTGCGGCG
GCGCATCCTGATCGAACTGAGCGAGGCGGATGTCTGCGCCCATCAGGCGCGTCTGGGTCCAATTCTGCGCCTGCTGCGTG
GGCTGGAGTGCCAGATAGTGGTCTCTCAGGCCGGGCTGCGCATCGTCAGTACCACCTATATCAAGCAGCTGCAGGTGGCG
CTGGTGAAACTGCATCCGGCGCTGGTGCGCAATATTGATCGGCGTATCGAAAACCAGCTGTTTGTTCAGAGTATCACTGG
CGCTTGCGAGGGTACCGTCGCACAGGTCTTCGCCACTGGGGTGCGTAGCAAAGAGGAGTGGCGGGTTCTCAGGGAGAAAG
GGATCGCCGGTGGTCAGGGGGATTTTTTTGCAAAATCACGACCGGTTCTCTAG

Upstream 100 bases:

>100_bases
AATTGTTTACTATTGAGGCAGACACTCTCCCCAGGCGGCGCACGCAGAGGGCGTCTTTTTTTCACGGCGATGACGCTTAA
CGGAATGGGTGGGGTCAGGG

Downstream 100 bases:

>100_bases
TCGGAAAAAATATTGTGACGGATAATGAATTGCGCTTTTTGTCAGGGAGAATTCACGTAGAATAACGTGTAATCTGTGCT
TCTACGGTTGGTGGGCGCTT

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MRITTKFFAFTTLLVVLGMFLMLLGSTYSFYSQTHQRAEIQLNILTAMIDQQLLTESRDSVKRWLPVMMRSAGAVELSVY
HDGSQVYYHHLPALYNPWRTDDNLRSFESPLLQHPGYRLKLVYIEPTDSYSHSLERMFPLSLSIGVMVIMLFIAYRWLRR
QTLGIERLDRRSRRILSGDRDLRVGGVGEFPASVSSALDCLLSELSDACEERSRIDSLIRAFAAQDSRTGLNNRLFFDNQ
LTTLLEDEGAHGVVMILRLPDLETLVSQPGRRQREEFRYALTNMLSTYVMRYPSGLLAHYFQNNFAVLLPHRSLKEAEGF
AAQLLASLAAIPSAPGVSTDEVLHIGITLYRAGEQVESVMDRAEQAARSATLQGGNGWFVDKTPQPEMVRGSVRWRTLLE
QTLARGGARLFHKPAVTVDGRVHHHYILPYIYDGNQPILSAEFMPLVQQLGLAERFDRQMVSQIIPLLRRLPGQRLAFPL
TVDSLLQRSFQRWLRDTLLQSERLLRRRILIELSEADVCAHQARLGPILRLLRGLECQIVVSQAGLRIVSTTYIKQLQVA
LVKLHPALVRNIDRRIENQLFVQSITGACEGTVAQVFATGVRSKEEWRVLREKGIAGGQGDFFAKSRPVL

Sequences:

>Translated_630_residues
MRITTKFFAFTTLLVVLGMFLMLLGSTYSFYSQTHQRAEIQLNILTAMIDQQLLTESRDSVKRWLPVMMRSAGAVELSVY
HDGSQVYYHHLPALYNPWRTDDNLRSFESPLLQHPGYRLKLVYIEPTDSYSHSLERMFPLSLSIGVMVIMLFIAYRWLRR
QTLGIERLDRRSRRILSGDRDLRVGGVGEFPASVSSALDCLLSELSDACEERSRIDSLIRAFAAQDSRTGLNNRLFFDNQ
LTTLLEDEGAHGVVMILRLPDLETLVSQPGRRQREEFRYALTNMLSTYVMRYPSGLLAHYFQNNFAVLLPHRSLKEAEGF
AAQLLASLAAIPSAPGVSTDEVLHIGITLYRAGEQVESVMDRAEQAARSATLQGGNGWFVDKTPQPEMVRGSVRWRTLLE
QTLARGGARLFHKPAVTVDGRVHHHYILPYIYDGNQPILSAEFMPLVQQLGLAERFDRQMVSQIIPLLRRLPGQRLAFPL
TVDSLLQRSFQRWLRDTLLQSERLLRRRILIELSEADVCAHQARLGPILRLLRGLECQIVVSQAGLRIVSTTYIKQLQVA
LVKLHPALVRNIDRRIENQLFVQSITGACEGTVAQVFATGVRSKEEWRVLREKGIAGGQGDFFAKSRPVL
>Mature_630_residues
MRITTKFFAFTTLLVVLGMFLMLLGSTYSFYSQTHQRAEIQLNILTAMIDQQLLTESRDSVKRWLPVMMRSAGAVELSVY
HDGSQVYYHHLPALYNPWRTDDNLRSFESPLLQHPGYRLKLVYIEPTDSYSHSLERMFPLSLSIGVMVIMLFIAYRWLRR
QTLGIERLDRRSRRILSGDRDLRVGGVGEFPASVSSALDCLLSELSDACEERSRIDSLIRAFAAQDSRTGLNNRLFFDNQ
LTTLLEDEGAHGVVMILRLPDLETLVSQPGRRQREEFRYALTNMLSTYVMRYPSGLLAHYFQNNFAVLLPHRSLKEAEGF
AAQLLASLAAIPSAPGVSTDEVLHIGITLYRAGEQVESVMDRAEQAARSATLQGGNGWFVDKTPQPEMVRGSVRWRTLLE
QTLARGGARLFHKPAVTVDGRVHHHYILPYIYDGNQPILSAEFMPLVQQLGLAERFDRQMVSQIIPLLRRLPGQRLAFPL
TVDSLLQRSFQRWLRDTLLQSERLLRRRILIELSEADVCAHQARLGPILRLLRGLECQIVVSQAGLRIVSTTYIKQLQVA
LVKLHPALVRNIDRRIENQLFVQSITGACEGTVAQVFATGVRSKEEWRVLREKGIAGGQGDFFAKSRPVL

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=633, Percent_Identity=50.0789889415482, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI87081921, Length=437, Percent_Identity=21.9679633867277, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788849, Length=387, Percent_Identity=21.1886304909561, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 71543; Mature: 71543

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITTKFFAFTTLLVVLGMFLMLLGSTYSFYSQTHQRAEIQLNILTAMIDQQLLTESRDS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRWLPVMMRSAGAVELSVYHDGSQVYYHHLPALYNPWRTDDNLRSFESPLLQHPGYRLK
HHHHHHHHHHCCCCEEEEEEECCCEEHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCEEE
LVYIEPTDSYSHSLERMFPLSLSIGVMVIMLFIAYRWLRRQTLGIERLDRRSRRILSGDR
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
DLRVGGVGEFPASVSSALDCLLSELSDACEERSRIDSLIRAFAAQDSRTGLNNRLFFDNQ
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCH
LTTLLEDEGAHGVVMILRLPDLETLVSQPGRRQREEFRYALTNMLSTYVMRYPSGLLAHY
HHHHHHCCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQNNFAVLLPHRSLKEAEGFAAQLLASLAAIPSAPGVSTDEVLHIGITLYRAGEQVESVM
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHEECCHHHHHHHH
DRAEQAARSATLQGGNGWFVDKTPQPEMVRGSVRWRTLLEQTLARGGARLFHKPAVTVDG
HHHHHHHHHCEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEECC
RVHHHYILPYIYDGNQPILSAEFMPLVQQLGLAERFDRQMVSQIIPLLRRLPGQRLAFPL
EEEEEEEEEEEECCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
TVDSLLQRSFQRWLRDTLLQSERLLRRRILIELSEADVCAHQARLGPILRLLRGLECQIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEE
VSQAGLRIVSTTYIKQLQVALVKLHPALVRNIDRRIENQLFVQSITGACEGTVAQVFATG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VRSKEEWRVLREKGIAGGQGDFFAKSRPVL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRITTKFFAFTTLLVVLGMFLMLLGSTYSFYSQTHQRAEIQLNILTAMIDQQLLTESRDS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRWLPVMMRSAGAVELSVYHDGSQVYYHHLPALYNPWRTDDNLRSFESPLLQHPGYRLK
HHHHHHHHHHCCCCEEEEEEECCCEEHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCEEE
LVYIEPTDSYSHSLERMFPLSLSIGVMVIMLFIAYRWLRRQTLGIERLDRRSRRILSGDR
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
DLRVGGVGEFPASVSSALDCLLSELSDACEERSRIDSLIRAFAAQDSRTGLNNRLFFDNQ
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCH
LTTLLEDEGAHGVVMILRLPDLETLVSQPGRRQREEFRYALTNMLSTYVMRYPSGLLAHY
HHHHHHCCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQNNFAVLLPHRSLKEAEGFAAQLLASLAAIPSAPGVSTDEVLHIGITLYRAGEQVESVM
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHEECCHHHHHHHH
DRAEQAARSATLQGGNGWFVDKTPQPEMVRGSVRWRTLLEQTLARGGARLFHKPAVTVDG
HHHHHHHHHCEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEECC
RVHHHYILPYIYDGNQPILSAEFMPLVQQLGLAERFDRQMVSQIIPLLRRLPGQRLAFPL
EEEEEEEEEEEECCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
TVDSLLQRSFQRWLRDTLLQSERLLRRRILIELSEADVCAHQARLGPILRLLRGLECQIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEE
VSQAGLRIVSTTYIKQLQVALVKLHPALVRNIDRRIENQLFVQSITGACEGTVAQVFATG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VRSKEEWRVLREKGIAGGQGDFFAKSRPVL
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]