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The map label for this gene is aaeA [H]

Identifier: 238921337

GI number: 238921337

Start: 3376148

End: 3377062

Strand: Reverse

Name: aaeA [H]

Synonym: NT01EI_3481

Alternate gene names: 238921337

Gene position: 3377062-3376148 (Counterclockwise)

Preceding gene: 238921338

Following gene: 238921336

Centisome position: 88.58

GC content: 67.98

Gene sequence:

>915_bases
ATGACGCGGGCGACCGTTACGCTGGCCTTACTGGCGCTGGCCGTACTGGCGGTCTCCAAGGCCTGGGTGTTCTATACCGC
CTCTCCCTGGACGCGGGATGCGCGTTTCAGCGCCGACGTGGTGGCCATCGCCCCCGACGTCAGTGGGCTGGTGGAAAGCG
TGCAGGTACAAGATAACCAGCGGGTGGCGCAGGGGGCGGTGCTGTTCCGCATCGATCCGCAGCGCTACCGCGCGGCGTTG
GCGCAGGCCGAGGCGGACGAGCGCTACTATCAGGCGCTGGTGACGGAGAAACGGCGAGAGTCGCAGCGCCGGGCCGATCT
GGGCGGACGTCTCGTCGCTCAGGAGAGCATCGATCTCGCCTACAGCGCGCTGGCGGCGGCCGAGCAACAGTTGGCCAGAG
CCCAGGCGACCCTGACCCTGGCGCAGCTGGATCTGGAGCGCACGGTGGTGCGGGCACCGGCCAGCGGCTGGGTGACCAAC
CTGCAGGTTCACGGCGGCGAGTTTATCAACCGCGGGGTTAACGCCGTGGCGCTGATTAAGCAGAACAGCTTTTACGTGCA
GGCCTATATGGAGGAGACCAAGCTGACGGGAGTCCGCCGCGGCTCACCGGTGCAGATCACGCCGCTGGGCAGCGATCGCA
TTCTGCACGGTACGGTGGACAGTATCTCCGCCGGGGTCAACGACGGCAGCGCGACGCCGGGGCGTAAAGGGTTGGCGACG
GTGGACTCCAATCTGGAGTGGGTACGTCTGGCGCAGCGGGTGCCGGTGCGTATTCGCCTGGATGCGGCGACCCAGGCGCA
TCCCTATCCGGCGGGTACCACGGCGACGGTAGTGATCGGCACCGGCGGTGAGGCGCAGGCCGCGCGCCCGGCGCCGTACC
GGCGTCTGCTGCAACGTCTGCGTGAGTTGGGCTGA

Upstream 100 bases:

>100_bases
CATCCCGCGCTGTTTAACTGCGCGCTGTACGGGTGTCTTTTTTATTTGGTGAGCTGGCTTTTTATCTGAAGGGGGTTCTG
TGAAGCGTTGGATTGGACGC

Downstream 100 bases:

>100_bases
GTCGGGGGCTAATATGCTGTATCCACGCGCGATCCGCCTGCGCTTTGCCTGCAAGCTGACGCTGGCAAGCGTTCTGTCGC
TGCTGCTCGGGTTCTATTTC

Product: p-hydroxybenzoic acid efflux subunit AaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTRATVTLALLALAVLAVSKAWVFYTASPWTRDARFSADVVAIAPDVSGLVESVQVQDNQRVAQGAVLFRIDPQRYRAAL
AQAEADERYYQALVTEKRRESQRRADLGGRLVAQESIDLAYSALAAAEQQLARAQATLTLAQLDLERTVVRAPASGWVTN
LQVHGGEFINRGVNAVALIKQNSFYVQAYMEETKLTGVRRGSPVQITPLGSDRILHGTVDSISAGVNDGSATPGRKGLAT
VDSNLEWVRLAQRVPVRIRLDAATQAHPYPAGTTATVVIGTGGEAQAARPAPYRRLLQRLRELG

Sequences:

>Translated_304_residues
MTRATVTLALLALAVLAVSKAWVFYTASPWTRDARFSADVVAIAPDVSGLVESVQVQDNQRVAQGAVLFRIDPQRYRAAL
AQAEADERYYQALVTEKRRESQRRADLGGRLVAQESIDLAYSALAAAEQQLARAQATLTLAQLDLERTVVRAPASGWVTN
LQVHGGEFINRGVNAVALIKQNSFYVQAYMEETKLTGVRRGSPVQITPLGSDRILHGTVDSISAGVNDGSATPGRKGLAT
VDSNLEWVRLAQRVPVRIRLDAATQAHPYPAGTTATVVIGTGGEAQAARPAPYRRLLQRLRELG
>Mature_303_residues
TRATVTLALLALAVLAVSKAWVFYTASPWTRDARFSADVVAIAPDVSGLVESVQVQDNQRVAQGAVLFRIDPQRYRAALA
QAEADERYYQALVTEKRRESQRRADLGGRLVAQESIDLAYSALAAAEQQLARAQATLTLAQLDLERTVVRAPASGWVTNL
QVHGGEFINRGVNAVALIKQNSFYVQAYMEETKLTGVRRGSPVQITPLGSDRILHGTVDSISAGVNDGSATPGRKGLATV
DSNLEWVRLAQRVPVRIRLDAATQAHPYPAGTTATVVIGTGGEAQAARPAPYRRLLQRLRELG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=304, Percent_Identity=59.8684210526316, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI87081951, Length=274, Percent_Identity=38.3211678832117, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1790519, Length=291, Percent_Identity=32.9896907216495, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788711, Length=339, Percent_Identity=26.2536873156342, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789041, Length=289, Percent_Identity=26.643598615917, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 32881; Mature: 32750

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRATVTLALLALAVLAVSKAWVFYTASPWTRDARFSADVVAIAPDVSGLVESVQVQDNQ
CCCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCC
RVAQGAVLFRIDPQRYRAALAQAEADERYYQALVTEKRRESQRRADLGGRLVAQESIDLA
HHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
YSALAAAEQQLARAQATLTLAQLDLERTVVRAPASGWVTNLQVHGGEFINRGVNAVALIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCEEEEEE
QNSFYVQAYMEETKLTGVRRGSPVQITPLGSDRILHGTVDSISAGVNDGSATPGRKGLAT
CCCEEEEEEEHHHHHCCCCCCCCEEEEECCCCCEEECCHHHHHCCCCCCCCCCCCCCCEE
VDSNLEWVRLAQRVPVRIRLDAATQAHPYPAGTTATVVIGTGGEAQAARPAPYRRLLQRL
ECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
RELG
HHCC
>Mature Secondary Structure 
TRATVTLALLALAVLAVSKAWVFYTASPWTRDARFSADVVAIAPDVSGLVESVQVQDNQ
CCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCC
RVAQGAVLFRIDPQRYRAALAQAEADERYYQALVTEKRRESQRRADLGGRLVAQESIDLA
HHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
YSALAAAEQQLARAQATLTLAQLDLERTVVRAPASGWVTNLQVHGGEFINRGVNAVALIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCEEEEEE
QNSFYVQAYMEETKLTGVRRGSPVQITPLGSDRILHGTVDSISAGVNDGSATPGRKGLAT
CCCEEEEEEEHHHHHCCCCCCCCEEEEECCCCCEEECCHHHHHCCCCCCCCCCCCCCCEE
VDSNLEWVRLAQRVPVRIRLDAATQAHPYPAGTTATVVIGTGGEAQAARPAPYRRLLQRL
ECCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH
RELG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA