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The map label for this gene is hypE [H]

Identifier: 238921145

GI number: 238921145

Start: 3164886

End: 3165914

Strand: Direct

Name: hypE [H]

Synonym: NT01EI_3286

Alternate gene names: 238921145

Gene position: 3164886-3165914 (Clockwise)

Preceding gene: 238921144

Following gene: 238921149

Centisome position: 83.02

GC content: 65.21

Gene sequence:

>1029_bases
ATGAGCAAATGGTCTGAAGACGATGTGATTACCATGGCGCACGGTAGCGGCGGCCTGGCGATGCAACAGCTGCTTGATAC
CCTGTTTTTACCGCTGTTTGACAATCCGGCGCTCAACGCCCGTGAAGATCAGGCACGCCTGCCGCTGTGCGGCTTTAACC
AGCTGGGCGATCGGCTGGCCTTCACTACCGACAGCTACGTGATCGATCCTATCTTCTTCCCCGGCGGTAACATCGGTAAG
CTGGCGGTCTGCGGCACGGCCAACGATCTGGCGGTCAGCGGCGCCTATCCCAGGTTTCTCTCCTGCGGCTTCATCCTGGA
AGAGGGGCTGCCGCTGCGCGATCTGGAGCAGGTGGTACAGAGCATGGCCCAGACGGCACACGACGCCGGGATCCAGATCG
TCACCGGCGATACCAAGGTGGTGCAACGCGGCGCGGCGGATAAGATCTTTATCAATACCGCCGGCATCGGCGCCATTCCG
GCAGATATCCGCTGGGCGGCCGCCGAGATCCAGCCGGGCGATCGTCTGATCGTCAGTGGCACCCTGGGCGATCACGGCGC
CACCATCCTCAATCTGCGGGAAAAGCTGGGGCTGGAGGCCGAGCTGAGCAGCGACTGCGCCGTGCTGGCGCCGCTGATAG
CACCGCTGCGCAACATCCCGGGCGTACGCGCCCTGCGCGATGCCACCCGTGGCGGCGTTACCGCTATTCTGCATGAGTTT
GCCCAGGCCAGCGGCTGCGGCATGGATGTCGACGAGAGGTCGCTGCCGGTGAAAGACGCGGTGCGCGGGATCTGCGAGCT
GCTGGGGCTGGAGCCGCTCAACTTCGCCAACGAGGGCAAGCTGGTGCTGGCCGTCGCGCCCGAGGCAGAGCAGGCGGTGC
TGGATTGCCTGCATGCCCACCCGCTGGGGATGGATGCCGCCACCATCGGCGTCGCCACCGATCGGCGTCAGGTGCGTCTG
GTCGGCCTGTTCGGTGCGGCGCGTCTGCTCGACCTGCCACACAGTGAACCGCTGCCGCGCATCTGCTGA

Upstream 100 bases:

>100_bases
CCCGCTGTAATCCCCAGAATGCCTTTGGCGCGCTGATGGTCTCTTCAGAAGGAGCCTGCGCGGCGTTCTACCAATATCGT
CGAGGAATGGAGCAATAAGC

Downstream 100 bases:

>100_bases
TAGCGGATCGACACCGGGCATCTCCGCCCGGTGTTTTCCCCCGGGTATCAGGCGGGAAGGTTACCGCCCCAGCGGGCAAA
CAGCACCTCATGCAGCGGAC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSKWSEDDVITMAHGSGGLAMQQLLDTLFLPLFDNPALNAREDQARLPLCGFNQLGDRLAFTTDSYVIDPIFFPGGNIGK
LAVCGTANDLAVSGAYPRFLSCGFILEEGLPLRDLEQVVQSMAQTAHDAGIQIVTGDTKVVQRGAADKIFINTAGIGAIP
ADIRWAAAEIQPGDRLIVSGTLGDHGATILNLREKLGLEAELSSDCAVLAPLIAPLRNIPGVRALRDATRGGVTAILHEF
AQASGCGMDVDERSLPVKDAVRGICELLGLEPLNFANEGKLVLAVAPEAEQAVLDCLHAHPLGMDAATIGVATDRRQVRL
VGLFGAARLLDLPHSEPLPRIC

Sequences:

>Translated_342_residues
MSKWSEDDVITMAHGSGGLAMQQLLDTLFLPLFDNPALNAREDQARLPLCGFNQLGDRLAFTTDSYVIDPIFFPGGNIGK
LAVCGTANDLAVSGAYPRFLSCGFILEEGLPLRDLEQVVQSMAQTAHDAGIQIVTGDTKVVQRGAADKIFINTAGIGAIP
ADIRWAAAEIQPGDRLIVSGTLGDHGATILNLREKLGLEAELSSDCAVLAPLIAPLRNIPGVRALRDATRGGVTAILHEF
AQASGCGMDVDERSLPVKDAVRGICELLGLEPLNFANEGKLVLAVAPEAEQAVLDCLHAHPLGMDAATIGVATDRRQVRL
VGLFGAARLLDLPHSEPLPRIC
>Mature_341_residues
SKWSEDDVITMAHGSGGLAMQQLLDTLFLPLFDNPALNAREDQARLPLCGFNQLGDRLAFTTDSYVIDPIFFPGGNIGKL
AVCGTANDLAVSGAYPRFLSCGFILEEGLPLRDLEQVVQSMAQTAHDAGIQIVTGDTKVVQRGAADKIFINTAGIGAIPA
DIRWAAAEIQPGDRLIVSGTLGDHGATILNLREKLGLEAELSSDCAVLAPLIAPLRNIPGVRALRDATRGGVTAILHEFA
QASGCGMDVDERSLPVKDAVRGICELLGLEPLNFANEGKLVLAVAPEAEQAVLDCLHAHPLGMDAATIGVATDRRQVRLV
GLFGAARLLDLPHSEPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=333, Percent_Identity=70.5705705705706, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36208; Mature: 36077

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKWSEDDVITMAHGSGGLAMQQLLDTLFLPLFDNPALNAREDQARLPLCGFNQLGDRLA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCEEE
FTTDSYVIDPIFFPGGNIGKLAVCGTANDLAVSGAYPRFLSCGFILEEGLPLRDLEQVVQ
EECCCEEECEEEECCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHHCCCCHHHHHHHHH
SMAQTAHDAGIQIVTGDTKVVQRGAADKIFINTAGIGAIPADIRWAAAEIQPGDRLIVSG
HHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEE
TLGDHGATILNLREKLGLEAELSSDCAVLAPLIAPLRNIPGVRALRDATRGGVTAILHEF
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
AQASGCGMDVDERSLPVKDAVRGICELLGLEPLNFANEGKLVLAVAPEAEQAVLDCLHAH
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCC
PLGMDAATIGVATDRRQVRLVGLFGAARLLDLPHSEPLPRIC
CCCCCCEEEEEECCCCEEEEEEEHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKWSEDDVITMAHGSGGLAMQQLLDTLFLPLFDNPALNAREDQARLPLCGFNQLGDRLA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCEEE
FTTDSYVIDPIFFPGGNIGKLAVCGTANDLAVSGAYPRFLSCGFILEEGLPLRDLEQVVQ
EECCCEEECEEEECCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHHCCCCHHHHHHHHH
SMAQTAHDAGIQIVTGDTKVVQRGAADKIFINTAGIGAIPADIRWAAAEIQPGDRLIVSG
HHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEE
TLGDHGATILNLREKLGLEAELSSDCAVLAPLIAPLRNIPGVRALRDATRGGVTAILHEF
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
AQASGCGMDVDERSLPVKDAVRGICELLGLEPLNFANEGKLVLAVAPEAEQAVLDCLHAH
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCC
PLGMDAATIGVATDRRQVRLVGLFGAARLLDLPHSEPLPRIC
CCCCCCEEEEEECCCCEEEEEEEHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]