Click here to switch to the map view.

The map label for this gene is mprA [H]

Identifier: 238920963

GI number: 238920963

Start: 2980444

End: 2980962

Strand: Direct

Name: mprA [H]

Synonym: NT01EI_3093

Alternate gene names: 238920963

Gene position: 2980444-2980962 (Clockwise)

Preceding gene: 238920962

Following gene: 238920964

Centisome position: 78.18

GC content: 52.22

Gene sequence:

>519_bases
ATGCCACGTTCTATCGCTCAAATCGAAGAGATGCTAAAGCAGCGCGCTAAGCGGCAGCTGGATTTTCCCTATCAGGAGAT
CCTGCTGACCCGCCTGTGTATGCATATGCAGAATAAGTTGCTGGAAAATCGCAACAAGATGCTGAAAGAACAAGGGATTA
ATGAAACGCTGTTCATGGCGATGATTACGCTGGATGCGCAGGAAGACTATAGTATTCAACCCTCTGAGCTGAGCGCGGCG
CTGGGATCATCACGTACCAACGCGACCCGTATCGCAGATGAGCTGGAGAGACGCGGCTGGATTGAGCGCCGCGAAAGCGA
CAACGATCGCCGCTGCCTACATCTGCATCTGACGGAGGCTGGCAGGGCGTTTCTAGCTGAGATCCTTCCGCCACAGCATA
AGTGTCTACACTTCTTATGGGCAACGTTGACTCAGGAGGAGCAGCAACAGTTGGAGATGTTGACGCGTAAGCTGTTATCA
CGCATTGAAGATATGGAGCAGTCCGGATTGCCACAGTAA

Upstream 100 bases:

>100_bases
ATTTATTAGCACGCGGCTTAGCTTTTTTCGCAAAAACACCGTTTACAACACTGATAACTGAAGTTACTATACCCAACGAA
ACTAATGAGGTCATTATCCA

Downstream 100 bases:

>100_bases
GCCATTCACCTGAAATTATGCTTACCGTTACCTAGAAGATCGCGCGTTTGTATCGCCAGCCCCTGGGCTACTCCGAACGA
CGCGCGGTCTGGCCCGCCAT

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPRSIAQIEEMLKQRAKRQLDFPYQEILLTRLCMHMQNKLLENRNKMLKEQGINETLFMAMITLDAQEDYSIQPSELSAA
LGSSRTNATRIADELERRGWIERRESDNDRRCLHLHLTEAGRAFLAEILPPQHKCLHFLWATLTQEEQQQLEMLTRKLLS
RIEDMEQSGLPQ

Sequences:

>Translated_172_residues
MPRSIAQIEEMLKQRAKRQLDFPYQEILLTRLCMHMQNKLLENRNKMLKEQGINETLFMAMITLDAQEDYSIQPSELSAA
LGSSRTNATRIADELERRGWIERRESDNDRRCLHLHLTEAGRAFLAEILPPQHKCLHFLWATLTQEEQQQLEMLTRKLLS
RIEDMEQSGLPQ
>Mature_171_residues
PRSIAQIEEMLKQRAKRQLDFPYQEILLTRLCMHMQNKLLENRNKMLKEQGINETLFMAMITLDAQEDYSIQPSELSAAL
GSSRTNATRIADELERRGWIERRESDNDRRCLHLHLTEAGRAFLAEILPPQHKCLHFLWATLTQEEQQQLEMLTRKLLSR
IEDMEQSGLPQ

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=170, Percent_Identity=75.8823529411765, Blast_Score=266, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 20232; Mature: 20100

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSIAQIEEMLKQRAKRQLDFPYQEILLTRLCMHMQNKLLENRNKMLKEQGINETLFMA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MITLDAQEDYSIQPSELSAALGSSRTNATRIADELERRGWIERRESDNDRRCLHLHLTEA
HHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
GRAFLAEILPPQHKCLHFLWATLTQEEQQQLEMLTRKLLSRIEDMEQSGLPQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRSIAQIEEMLKQRAKRQLDFPYQEILLTRLCMHMQNKLLENRNKMLKEQGINETLFMA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MITLDAQEDYSIQPSELSAALGSSRTNATRIADELERRGWIERRESDNDRRCLHLHLTEA
HHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
GRAFLAEILPPQHKCLHFLWATLTQEEQQQLEMLTRKLLSRIEDMEQSGLPQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]