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The map label for this gene is hoxN [H]

Identifier: 238920826

GI number: 238920826

Start: 2839586

End: 2840617

Strand: Direct

Name: hoxN [H]

Synonym: NT01EI_2952

Alternate gene names: 238920826

Gene position: 2839586-2840617 (Clockwise)

Preceding gene: 238920822

Following gene: 238920827

Centisome position: 74.48

GC content: 63.18

Gene sequence:

>1032_bases
ATGAAAGGGTATTCGGACAAACAACGGGGGCTGGCACTGCTGGCCCTGCTGATCGCGGCCAACCTCGCCGCCTGGATCTG
GGCCTTTTGCGTCTTTCGCCAGCACGCCGTCATGATGAGCGCAGCGCTGCTGGCCTATGGCTTTGGCCTGCGCCACGCGG
TGGACGCCGACCATATTGCCGCCATCGATGCCGTCACACGTAAGCTGATGCAGCAGGGGAAAAAACCGCTCGGCGTCGGC
GCCTTCTTCTCCCTGGGCCACTCCACCATTGTGATTCTGGCCTGTCTGGCCATCGTACTGACGTCGATGGCGTTTCGCGA
TCGCATCGATGCCCTGCACCAGTACGGCGGGCTGATCGGTACCGCAGTCTCTGCGCTGTTCCTGCTGGCGATGGGGCTGC
TGAACCTGCTGATCCTGCTGAGCGTCTGGCGCCAGTTCCGTCGTCTCACCCGCCACGGCGCATCGGTGGGCGAGGCACCG
TGGGACGATGGGCTACCCGGCGGCCTGATGACCCGCCTGTTCCACCGCACCTTCCGCCTGGTTACCCGCAGCTGGCACAT
GTACCTGGTGGGATTCCTGTTCGGCCTCGGGTTTGACACCGCCACCGAAGTCGGCCTGCTGGGGATCTCAGCCTCTGCCG
CGACCCACGGGCTCTCCCTGTGGTCGCTGATGGTATTCCCGGCGCTGTTTACCGCCGGTATGGCGCTGGTGGATTCGTTG
GATAACTTTGTGATGGTCGGGGCCTACGGCTGGGCCTTTTCCCACCCGATCCGCAAGCTGTACTACAACATGACCATCAC
CGCCGCCTCGGTCGCCGTCGCGCTGATCATCGGTGGCCTGGAGGCACTGGGGCTGATGGCTGATAGCCTGCAGTTGCAGG
GAGGCTTCTGGCAGATGATAGGCAGCCTTAATGACAGGATGGGCAACGCCGGCTTCTGGGTTATCGGCGGCTTTATCCTG
TTCTGGCTGCTGTCGCTGCTCAACTACCGCTGGCGCGGCTACGACCGCATCACCCTGAGTGCCGTTGAGTAA

Upstream 100 bases:

>100_bases
CATACATTCCCTTCCCGTAACGGACGGTCTGCGAGCATTCCCCACCGCCTGCCCCTCACCAAATCGACGCCATCGGCGCC
TCTACGGGAGAACACAGCAA

Downstream 100 bases:

>100_bases
AGTTACAATTCGTGCCGTGATCTGCTGCAACATTAACGCTATGATCGTCCTGTCCGGTCCACCGAGCTCCCCGCCCGGCG
CCCGGTAACAGGGAGAACAG

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKGYSDKQRGLALLALLIAANLAAWIWAFCVFRQHAVMMSAALLAYGFGLRHAVDADHIAAIDAVTRKLMQQGKKPLGVG
AFFSLGHSTIVILACLAIVLTSMAFRDRIDALHQYGGLIGTAVSALFLLAMGLLNLLILLSVWRQFRRLTRHGASVGEAP
WDDGLPGGLMTRLFHRTFRLVTRSWHMYLVGFLFGLGFDTATEVGLLGISASAATHGLSLWSLMVFPALFTAGMALVDSL
DNFVMVGAYGWAFSHPIRKLYYNMTITAASVAVALIIGGLEALGLMADSLQLQGGFWQMIGSLNDRMGNAGFWVIGGFIL
FWLLSLLNYRWRGYDRITLSAVE

Sequences:

>Translated_343_residues
MKGYSDKQRGLALLALLIAANLAAWIWAFCVFRQHAVMMSAALLAYGFGLRHAVDADHIAAIDAVTRKLMQQGKKPLGVG
AFFSLGHSTIVILACLAIVLTSMAFRDRIDALHQYGGLIGTAVSALFLLAMGLLNLLILLSVWRQFRRLTRHGASVGEAP
WDDGLPGGLMTRLFHRTFRLVTRSWHMYLVGFLFGLGFDTATEVGLLGISASAATHGLSLWSLMVFPALFTAGMALVDSL
DNFVMVGAYGWAFSHPIRKLYYNMTITAASVAVALIIGGLEALGLMADSLQLQGGFWQMIGSLNDRMGNAGFWVIGGFIL
FWLLSLLNYRWRGYDRITLSAVE
>Mature_343_residues
MKGYSDKQRGLALLALLIAANLAAWIWAFCVFRQHAVMMSAALLAYGFGLRHAVDADHIAAIDAVTRKLMQQGKKPLGVG
AFFSLGHSTIVILACLAIVLTSMAFRDRIDALHQYGGLIGTAVSALFLLAMGLLNLLILLSVWRQFRRLTRHGASVGEAP
WDDGLPGGLMTRLFHRTFRLVTRSWHMYLVGFLFGLGFDTATEVGLLGISASAATHGLSLWSLMVFPALFTAGMALVDSL
DNFVMVGAYGWAFSHPIRKLYYNMTITAASVAVALIIGGLEALGLMADSLQLQGGFWQMIGSLNDRMGNAGFWVIGGFIL
FWLLSLLNYRWRGYDRITLSAVE

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37468; Mature: 37468

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGYSDKQRGLALLALLIAANLAAWIWAFCVFRQHAVMMSAALLAYGFGLRHAVDADHIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AIDAVTRKLMQQGKKPLGVGAFFSLGHSTIVILACLAIVLTSMAFRDRIDALHQYGGLIG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TAVSALFLLAMGLLNLLILLSVWRQFRRLTRHGASVGEAPWDDGLPGGLMTRLFHRTFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTRSWHMYLVGFLFGLGFDTATEVGLLGISASAATHGLSLWSLMVFPALFTAGMALVDSL
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNFVMVGAYGWAFSHPIRKLYYNMTITAASVAVALIIGGLEALGLMADSLQLQGGFWQMI
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GSLNDRMGNAGFWVIGGFILFWLLSLLNYRWRGYDRITLSAVE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MKGYSDKQRGLALLALLIAANLAAWIWAFCVFRQHAVMMSAALLAYGFGLRHAVDADHIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AIDAVTRKLMQQGKKPLGVGAFFSLGHSTIVILACLAIVLTSMAFRDRIDALHQYGGLIG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TAVSALFLLAMGLLNLLILLSVWRQFRRLTRHGASVGEAPWDDGLPGGLMTRLFHRTFRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTRSWHMYLVGFLFGLGFDTATEVGLLGISASAATHGLSLWSLMVFPALFTAGMALVDSL
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNFVMVGAYGWAFSHPIRKLYYNMTITAASVAVALIIGGLEALGLMADSLQLQGGFWQMI
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GSLNDRMGNAGFWVIGGFILFWLLSLLNYRWRGYDRITLSAVE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]