Click here to switch to the map view.

The map label for this gene is gltK [H]

Identifier: 238920805

GI number: 238920805

Start: 2820625

End: 2821302

Strand: Direct

Name: gltK [H]

Synonym: NT01EI_2931

Alternate gene names: 238920805

Gene position: 2820625-2821302 (Clockwise)

Preceding gene: 238920804

Following gene: 238920806

Centisome position: 73.99

GC content: 59.14

Gene sequence:

>678_bases
ATGTACGCATTTGACTGGAGTTCCATTGTCCCCAGCCTGCCCTACCTGCTGGATGGGTTGGTTATCACGCTGAAGATAAC
GCTGACAGCGGTGGTAGTCGGCATTCTATGGGGAACCCTGCTGGCCGTAATGCGGCTGTCACGCTGGAAACCCCTCGCCT
GGCTGGCGGCCCTGTATGTCAATCTGTTCCGCTCGGTACCGCTGGTGATGGTGCTGCTGTGGTTCTATCTGGTGGTACCC
AGCCTGCTACAGCGCTTTCTCGGCCTGTCGCCGCAAAGCGATATCCGTCTTATCTCGGCGATGGTGGCCTTTGCGCTGTT
CGAAGCCGCCTACTACTCGGAGATTATCCGCGCCGGTATCAAGAGCGTTGCGCGCGGACAGAACGCCGCCGCACTGGCGC
TGGGCATGACTCCCTGGCAATCCATGTATCTGGTCATCCTGCCACAGGCGTTCCGCGCCATGGTGCCGCTGCTGCTGACG
CAGGGTATCGTGCTGTTTCAGGACACCTCATTGGTGTACGTTTTGAGTCTGGCGGACTTCTTCCGTACCGCCTCCACCAT
CGGCGAGCGCGATGGCACCCAGCTGGAAATGATCCTGTTTGCCGGCGCCGTCTACTTCATCATCAGCCTCAGCGCCTCGC
TGCTGGTCGGCCATCTCAAGAAAAGGAGTACCTTATGA

Upstream 100 bases:

>100_bases
CTATCACGCTGGCCTACATCGCCATCAATGCCCTGCTAATGCTGGGCATGCATCTGCTGGAACGGCATCTGCAATTGCCT
GGCAGTATGAGGAGCCATTA

Downstream 100 bases:

>100_bases
TCTCCCTGCAACAGGTCAGTAAATGGTATGGGCAGTTTCAGGTGCTGAACGACTGCAGCACCCACGTCGACAAAGGCGAG
GTGGTGGTGGTTTGCGGTCC

Product: glutamate-aspartate transport system permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MYAFDWSSIVPSLPYLLDGLVITLKITLTAVVVGILWGTLLAVMRLSRWKPLAWLAALYVNLFRSVPLVMVLLWFYLVVP
SLLQRFLGLSPQSDIRLISAMVAFALFEAAYYSEIIRAGIKSVARGQNAAALALGMTPWQSMYLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQLEMILFAGAVYFIISLSASLLVGHLKKRSTL

Sequences:

>Translated_225_residues
MYAFDWSSIVPSLPYLLDGLVITLKITLTAVVVGILWGTLLAVMRLSRWKPLAWLAALYVNLFRSVPLVMVLLWFYLVVP
SLLQRFLGLSPQSDIRLISAMVAFALFEAAYYSEIIRAGIKSVARGQNAAALALGMTPWQSMYLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQLEMILFAGAVYFIISLSASLLVGHLKKRSTL
>Mature_225_residues
MYAFDWSSIVPSLPYLLDGLVITLKITLTAVVVGILWGTLLAVMRLSRWKPLAWLAALYVNLFRSVPLVMVLLWFYLVVP
SLLQRFLGLSPQSDIRLISAMVAFALFEAAYYSEIIRAGIKSVARGQNAAALALGMTPWQSMYLVILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQLEMILFAGAVYFIISLSASLLVGHLKKRSTL

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=223, Percent_Identity=83.4080717488789, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=38.3177570093458, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=33.1730769230769, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787030, Length=222, Percent_Identity=30.1801801801802, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786874, Length=172, Percent_Identity=32.5581395348837, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787087, Length=219, Percent_Identity=26.9406392694064, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=35.2459016393443, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788645, Length=221, Percent_Identity=27.6018099547511, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=24.6445497630332, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=23.1481481481481, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24939; Mature: 24939

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAFDWSSIVPSLPYLLDGLVITLKITLTAVVVGILWGTLLAVMRLSRWKPLAWLAALYV
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NLFRSVPLVMVLLWFYLVVPSLLQRFLGLSPQSDIRLISAMVAFALFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSVARGQNAAALALGMTPWQSMYLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQLEMILFAGAVYFIISLSASLLVGHLKKRSTL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYAFDWSSIVPSLPYLLDGLVITLKITLTAVVVGILWGTLLAVMRLSRWKPLAWLAALYV
CCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NLFRSVPLVMVLLWFYLVVPSLLQRFLGLSPQSDIRLISAMVAFALFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSVARGQNAAALALGMTPWQSMYLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADF
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
FRTASTIGERDGTQLEMILFAGAVYFIISLSASLLVGHLKKRSTL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]