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The map label for this gene is corC [H]

Identifier: 238920801

GI number: 238920801

Start: 2816109

End: 2816996

Strand: Direct

Name: corC [H]

Synonym: NT01EI_2927

Alternate gene names: 238920801

Gene position: 2816109-2816996 (Clockwise)

Preceding gene: 238920800

Following gene: 238920802

Centisome position: 73.87

GC content: 55.07

Gene sequence:

>888_bases
ATGAGCGACGACCATTCTCAGAATAGCGACAACCCCAGTCCCCATAAGAAAGGCTTCTTTTCCCTTTTGCTCAACCAACT
GTTTCACGGTGAACCCAAGAACCGCAGCGATCTGGTGGAGCTTATCCGCGACTCCGAGCAGAACGATCTTATTGACCCCG
ATACCCGCGATATGCTGGAAGGGGTGATGGACATCGCCGAACAGCGCGTACGCGATATCATGATCCCACGCAGCCAGATG
GTTACCCTGAAACGTAACCAGACCCTGGACGAATGTCTGGATGTGATCATTGAGTCAGCCCACTCACGCTTTCCTGTGAT
CAGTGAGGACAAAGATCATATTGAAGGCGTGCTGATGGCCAAAGATCTGCTGCCCTTTATGCGCAGCGATGCCGAACCGT
TCAGCATCGATAAGGTGCTGCGCCAGGCCGTGGTCGTGCCGGAAAGCAAGCGCGTTGACCGCATGCTCAAAGAGTTCCGC
TCCCAGCGCTACCATATGGCCATCGTTATCGACGAATTCGGCAGCGTCTCCGGACTGGTCACTATTGAAGATATTCTGGA
GCTGATCGTCGGCGAGATCGACGATGAGTACGATGAGGTGGAGGATCGCGACGTGCGCCAGATCAGCCGCCATCTCTACA
CCGTTCGTGCGCTGACCCAGATCGAGGATTTCAACGACATCTTTGGCACCCGCTTCAATGATGACGAGGTCGATACCATC
GGCGGCCTGGTGATGCAGGCCTTCGGCCATCTTCCGGCGCGTGGAGAGAGCACCGACATCGACGGTTACCTGTTTAAGGT
CGCCATGGCCGACAGTCGACGTATCATACAGGTTCATGTCAAAATTCCGGATGCATCACCTCAACCGCAACTGGACCTGG
AACCCTGA

Upstream 100 bases:

>100_bases
GAGTCCGACTGAACGACCCCCCGGGGTCACGTTTGCGGTGGCCGCTGCACAGCGCCACCGTTAAGATTGACCAGACTAAG
AGTAACCATACATATACGCT

Downstream 100 bases:

>100_bases
ATAACCGATGACCATCGCCGCTTTACTGCAACGCCAGCGGGTACGCGCCCCGCTGGCGCTGATAACCGGTGCCTGTGGCA
CCCTGGCCTTTTCGCCCTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSDDHSQNSDNPSPHKKGFFSLLLNQLFHGEPKNRSDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQM
VTLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGVLMAKDLLPFMRSDAEPFSIDKVLRQAVVVPESKRVDRMLKEFR
SQRYHMAIVIDEFGSVSGLVTIEDILELIVGEIDDEYDEVEDRDVRQISRHLYTVRALTQIEDFNDIFGTRFNDDEVDTI
GGLVMQAFGHLPARGESTDIDGYLFKVAMADSRRIIQVHVKIPDASPQPQLDLEP

Sequences:

>Translated_295_residues
MSDDHSQNSDNPSPHKKGFFSLLLNQLFHGEPKNRSDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQM
VTLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGVLMAKDLLPFMRSDAEPFSIDKVLRQAVVVPESKRVDRMLKEFR
SQRYHMAIVIDEFGSVSGLVTIEDILELIVGEIDDEYDEVEDRDVRQISRHLYTVRALTQIEDFNDIFGTRFNDDEVDTI
GGLVMQAFGHLPARGESTDIDGYLFKVAMADSRRIIQVHVKIPDASPQPQLDLEP
>Mature_294_residues
SDDHSQNSDNPSPHKKGFFSLLLNQLFHGEPKNRSDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQMV
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGVLMAKDLLPFMRSDAEPFSIDKVLRQAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGSVSGLVTIEDILELIVGEIDDEYDEVEDRDVRQISRHLYTVRALTQIEDFNDIFGTRFNDDEVDTIG
GLVMQAFGHLPARGESTDIDGYLFKVAMADSRRIIQVHVKIPDASPQPQLDLEP

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=32.5242718446602, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI94681046, Length=187, Percent_Identity=31.5508021390374, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40068053, Length=195, Percent_Identity=29.7435897435897, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40068055, Length=195, Percent_Identity=29.7435897435897, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=86.3013698630137, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI87082033, Length=248, Percent_Identity=28.2258064516129, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788119, Length=222, Percent_Identity=31.5315315315315, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI145693175, Length=221, Percent_Identity=26.2443438914027, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790664, Length=246, Percent_Identity=24.390243902439, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33761; Mature: 33629

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDHSQNSDNPSPHKKGFFSLLLNQLFHGEPKNRSDLVELIRDSEQNDLIDPDTRDMLE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
GVMDIAEQRVRDIMIPRSQMVTLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGVLMA
HHHHHHHHHHHHHHCCHHHHEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KDLLPFMRSDAEPFSIDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGSVSGLV
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCE
TIEDILELIVGEIDDEYDEVEDRDVRQISRHLYTVRALTQIEDFNDIFGTRFNDDEVDTI
EHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GGLVMQAFGHLPARGESTDIDGYLFKVAMADSRRIIQVHVKIPDASPQPQLDLEP
HHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDHSQNSDNPSPHKKGFFSLLLNQLFHGEPKNRSDLVELIRDSEQNDLIDPDTRDMLE
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
GVMDIAEQRVRDIMIPRSQMVTLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGVLMA
HHHHHHHHHHHHHHCCHHHHEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KDLLPFMRSDAEPFSIDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGSVSGLV
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCE
TIEDILELIVGEIDDEYDEVEDRDVRQISRHLYTVRALTQIEDFNDIFGTRFNDDEVDTI
EHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
GGLVMQAFGHLPARGESTDIDGYLFKVAMADSRRIIQVHVKIPDASPQPQLDLEP
HHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]