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The map label for this gene is clpX [H]

Identifier: 238917542

GI number: 238917542

Start: 1678214

End: 1679620

Strand: Reverse

Name: clpX [H]

Synonym: EUBELI_01621

Alternate gene names: 238917542

Gene position: 1679620-1678214 (Counterclockwise)

Preceding gene: 238917543

Following gene: 238917541

Centisome position: 78.33

GC content: 37.31

Gene sequence:

>1407_bases
ATGGATAATACCAATGAGAATATGACAGAAGATAAGGATATTAATAAGAATAACAATGGGAATTCCGATGATTATGAGAA
GATATGTTTTGTGTGCAGAAGACCAGAATCAAGAGCTGGTAAGATGATTGTTATGCCTAACAATATATACATCTGTCAGG
ATTGTATGCAAAGAACATTCGATTCAATTAACAGCAGCGGAATTAATTATGAAGATATGATGAAGATGTCAAACATGCCT
GGAATGGGCATGTTTGGCAATTTTGGCGTTATGGATTCAGACCCGGTTCCAGAAAAGCAGAAGCTTAAGAAAAAGAAAGA
AGATAAGAAAGAGTTACCTGCTCTTGATGTTTCTAAGCTGCCTGCACCACATGAGATTAAGAGAAAGTTAGATGAGTATG
TTATAGGTCAGGACTATGCTAAGAAGGTAATGTCGGTGGCTGTATATAATCATTATAAAAGAGTTTCAGCAGATGCCAGG
ATTCTGGGTGACGTTGAGATTGAGAAGTCTAATATGCTTATGATTGGACCTACAGGAAGTGGTAAGACATATCTTGTTAA
GACGCTTGCAAGGATATTACAGGTGCCACTTGCTATTACAGATGCAACAACACTTACAGAGGCAGGATATATCGGAGATG
ATATAGAGTCAGTTGTTTCTAAGCTTTTACTGGCAGCAGACAATGATGTAGAGAAAGCTGAACATGGAATTATATTTATT
GATGAGATAGACAAGATTGCCAAGAAGAAAGAGACCAGAAGCAGAGATGTAAGTGGTGAGTCTGTACAGCAGGGAATGTT
AAAGCTGTTAGAAGGCAGTGAGATTGAAGTTCCTGTTGGTGCGACAAGTAAGAATGCAATGGTTCCACAGGTAACTGTTA
ACACGAAGGATATTCTGTTTATATGTGGTGGTGCATTTCCAGATCTTGAGGATATTATCAAGACAAGGCTTAATAAGTCA
TCCTCAATGGGATTTAATGCTGACCTTAAAGATAAATATGATGATGAGAAGAACATCATGTCTTATGTGACGGTTGATGA
TCTTAGAGAATACGGAATGATTCCAGAATTTTTAGGAAGACTGCCTATCATATATTCACTTGACAGACTGGATGAGGATA
TGCTTGTCAATATTCTGAAAGAGCCTAAGAATGCAATTCTTAAGCAGTATCAGAAGCTGTTAGAGCTTGATGAGGTGAAG
CTTGAATTTACAGATGATGCATTAAGAAGCATAGCAAGAAAGGCAATGGAAAAAGATACAGGTGCAAGAGCACTCCGTTC
TATTATTGAGGATTTTATGCTTGATATAATGTATGAGATACCTAAAGACAGCAATATAGGTTCAGTTACAATTACAGAAG
ATGTTGTTGAAAAGAAAGGTGCTCCGGTAATAACTATGAGAGCATAA

Upstream 100 bases:

>100_bases
ATTATTATCATATGGAAGGAAGCGAGTATGTTCTTAAGAGCACGGAGGTAACGCTTGGCTCTAAGAAGGCATCTTAAGGA
TATATTCCAAGTAGATATTT

Downstream 100 bases:

>100_bases
TAGTTATAGCAGAATAATACAATACATTTCTGAATACATATAGCATGTACAGTGATTGTTTTATGTTAAGGAGATGTTAT
GGCGTGTGATTTTGATATAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDNTNENMTEDKDINKNNNGNSDDYEKICFVCRRPESRAGKMIVMPNNIYICQDCMQRTFDSINSSGINYEDMMKMSNMP
GMGMFGNFGVMDSDPVPEKQKLKKKKEDKKELPALDVSKLPAPHEIKRKLDEYVIGQDYAKKVMSVAVYNHYKRVSADAR
ILGDVEIEKSNMLMIGPTGSGKTYLVKTLARILQVPLAITDATTLTEAGYIGDDIESVVSKLLLAADNDVEKAEHGIIFI
DEIDKIAKKKETRSRDVSGESVQQGMLKLLEGSEIEVPVGATSKNAMVPQVTVNTKDILFICGGAFPDLEDIIKTRLNKS
SSMGFNADLKDKYDDEKNIMSYVTVDDLREYGMIPEFLGRLPIIYSLDRLDEDMLVNILKEPKNAILKQYQKLLELDEVK
LEFTDDALRSIARKAMEKDTGARALRSIIEDFMLDIMYEIPKDSNIGSVTITEDVVEKKGAPVITMRA

Sequences:

>Translated_468_residues
MDNTNENMTEDKDINKNNNGNSDDYEKICFVCRRPESRAGKMIVMPNNIYICQDCMQRTFDSINSSGINYEDMMKMSNMP
GMGMFGNFGVMDSDPVPEKQKLKKKKEDKKELPALDVSKLPAPHEIKRKLDEYVIGQDYAKKVMSVAVYNHYKRVSADAR
ILGDVEIEKSNMLMIGPTGSGKTYLVKTLARILQVPLAITDATTLTEAGYIGDDIESVVSKLLLAADNDVEKAEHGIIFI
DEIDKIAKKKETRSRDVSGESVQQGMLKLLEGSEIEVPVGATSKNAMVPQVTVNTKDILFICGGAFPDLEDIIKTRLNKS
SSMGFNADLKDKYDDEKNIMSYVTVDDLREYGMIPEFLGRLPIIYSLDRLDEDMLVNILKEPKNAILKQYQKLLELDEVK
LEFTDDALRSIARKAMEKDTGARALRSIIEDFMLDIMYEIPKDSNIGSVTITEDVVEKKGAPVITMRA
>Mature_468_residues
MDNTNENMTEDKDINKNNNGNSDDYEKICFVCRRPESRAGKMIVMPNNIYICQDCMQRTFDSINSSGINYEDMMKMSNMP
GMGMFGNFGVMDSDPVPEKQKLKKKKEDKKELPALDVSKLPAPHEIKRKLDEYVIGQDYAKKVMSVAVYNHYKRVSADAR
ILGDVEIEKSNMLMIGPTGSGKTYLVKTLARILQVPLAITDATTLTEAGYIGDDIESVVSKLLLAADNDVEKAEHGIIFI
DEIDKIAKKKETRSRDVSGESVQQGMLKLLEGSEIEVPVGATSKNAMVPQVTVNTKDILFICGGAFPDLEDIIKTRLNKS
SSMGFNADLKDKYDDEKNIMSYVTVDDLREYGMIPEFLGRLPIIYSLDRLDEDMLVNILKEPKNAILKQYQKLLELDEVK
LEFTDDALRSIARKAMEKDTGARALRSIIEDFMLDIMYEIPKDSNIGSVTITEDVVEKKGAPVITMRA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=323, Percent_Identity=46.749226006192, Blast_Score=280, Evalue=3e-75,
Organism=Escherichia coli, GI1786642, Length=440, Percent_Identity=44.5454545454545, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1790366, Length=230, Percent_Identity=33.0434782608696, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=306, Percent_Identity=42.156862745098, Blast_Score=258, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI71982905, Length=307, Percent_Identity=42.0195439739414, Blast_Score=258, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=414, Percent_Identity=36.4734299516908, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=39.2, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=38.1733021077283, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24648291, Length=316, Percent_Identity=47.7848101265823, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24648289, Length=316, Percent_Identity=47.7848101265823, Blast_Score=281, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 52557; Mature: 52557

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTNENMTEDKDINKNNNGNSDDYEKICFVCRRPESRAGKMIVMPNNIYICQDCMQRTF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCEEEECCCEEEHHHHHHHHH
DSINSSGINYEDMMKMSNMPGMGMFGNFGVMDSDPVPEKQKLKKKKEDKKELPALDVSKL
HHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHC
PAPHEIKRKLDEYVIGQDYAKKVMSVAVYNHYKRVSADARILGDVEIEKSNMLMIGPTGS
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCEEEEECCCC
GKTYLVKTLARILQVPLAITDATTLTEAGYIGDDIESVVSKLLLAADNDVEKAEHGIIFI
CCHHHHHHHHHHHHCCHHEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKKETRSRDVSGESVQQGMLKLLEGSEIEVPVGATSKNAMVPQVTVNTKDILF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCEEEE
ICGGAFPDLEDIIKTRLNKSSSMGFNADLKDKYDDEKNIMSYVTVDDLREYGMIPEFLGR
EECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
LPIIYSLDRLDEDMLVNILKEPKNAILKQYQKLLELDEVKLEFTDDALRSIARKAMEKDT
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCH
GARALRSIIEDFMLDIMYEIPKDSNIGSVTITEDVVEKKGAPVITMRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCEEEECC
>Mature Secondary Structure
MDNTNENMTEDKDINKNNNGNSDDYEKICFVCRRPESRAGKMIVMPNNIYICQDCMQRTF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCEEEECCCEEEHHHHHHHHH
DSINSSGINYEDMMKMSNMPGMGMFGNFGVMDSDPVPEKQKLKKKKEDKKELPALDVSKL
HHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHC
PAPHEIKRKLDEYVIGQDYAKKVMSVAVYNHYKRVSADARILGDVEIEKSNMLMIGPTGS
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCEEEEECCCC
GKTYLVKTLARILQVPLAITDATTLTEAGYIGDDIESVVSKLLLAADNDVEKAEHGIIFI
CCHHHHHHHHHHHHCCHHEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKKETRSRDVSGESVQQGMLKLLEGSEIEVPVGATSKNAMVPQVTVNTKDILF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEECCCEEEE
ICGGAFPDLEDIIKTRLNKSSSMGFNADLKDKYDDEKNIMSYVTVDDLREYGMIPEFLGR
EECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
LPIIYSLDRLDEDMLVNILKEPKNAILKQYQKLLELDEVKLEFTDDALRSIARKAMEKDT
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCH
GARALRSIIEDFMLDIMYEIPKDSNIGSVTITEDVVEKKGAPVITMRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]