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The map label for this gene is gmr [H]

Identifier: 238917494

GI number: 238917494

Start: 1625774

End: 1627576

Strand: Reverse

Name: gmr [H]

Synonym: EUBELI_01572

Alternate gene names: 238917494

Gene position: 1627576-1625774 (Counterclockwise)

Preceding gene: 238917496

Following gene: 238917493

Centisome position: 75.91

GC content: 36.11

Gene sequence:

>1803_bases
ATGGATAATAAAGCGACAGAAAAAGAAAAATTTGAAATTGTACACAAGATGAGCAGGAGAATTGCATCTGTTGACAAATA
TTGTGTAGTAAGTGTTTCTAATAAAGCATTTGAAGAATATTTCGGACGCATTGTAGATACACTTCTTGAAGTGGTAGCAC
CACAGGATAAAGAAAGGCTGATAGATTTCATAGAAAATTATGATGGTACCGCCAAGAGTGGAATGTTTAAGTTTATTAAT
GCACAGGGAGAGGAAAGGTATAATCATCTTTTTGTGTATCAGCAGCGCGGTGCTGGCAATGGACATATGAGAGATATTGA
GATTGTCGATGTTGAATCAATAGAAGAAGCTAATAAGAGTCTCAGGGATGATGTATCAAAGCATAAGATGCTTCTTGGAT
TAGACCGTGAATACACATTTACATATAATAGGGATAATAATATTTTCAGTATGTACAGATATGATGTTGATTCACGAGAT
ATTATATACAAGGCTGATATTGATGACTGGAAGAGACAGATGCTTACAGAAGGATATATAGAGAAAAGTGATAAGGAAAT
GTTCACTAATTTTATATCTGAGGTGCGTTCATATACACAGACATTCTCAACAAAGTTTAAGACCAGCATGCGTACATATA
ACAAGGTTATGGAAACATTGAGATTCATCGGAACTGTTATGACCAAGAGCGATGGAAGAAAGATTGTTGTTGGCAGGGTT
ATTCCAGAGGCAGATAACCGTAGTTATAACCAGATTTCAGATATGATAGAAGAATTACAGTTTGATTCTCTTACGCATGT
ATATAATAAGAAAACAATAACTGCTTATGCTGTAAAGTGCCTTAAAGAAGAAAAGAATAACAGGGTCACAATAGCTGTTC
TTGATGTGGATCATTTTAAGAAGGTCAATGATGTGTATGGCCATATGTATGGAGATAAGATTCTTGCAAGAGTAGGACGA
AAGCTTAAGGAAGTAGTCGGTGAGGATGGAGTCGTCGGAAGAATAGGTGGCGATGAATTTATCATTGTGTTTAATGGAAT
TAATGATGAGCATGCGTTGCGAGGAATGTTAAGAGCAATAAGAACGCAGATTAAATGGGAATTTGTTGATGATTTTGAAG
ACCTGATGATAACATGTTCTATCGGAGCATCATATAGTCCAAATAATGGCACAGAATACGAAGAGCTTTTCAAAAAAGCT
GATTATTGTCTGTATGTTGCTAAGGAAAAGGGAAGAGACAGATATGTATTTTTCAGAGATGATCTTCATAAGGAATCGTA
TGAGAATTCGCTTAATACAAAGGATAAGAATGTTAATGATGGCAGAGAGATGAAAGAACTTCGTTTTCTGTCAGGAATAA
TGGAAGAATTTGCACAGGATGGAAGAAAAGCTGTTGATGAACTGCTTCATCATATGTATGATTCTTTTAAGCTTGACAGT
ATTAATCTGTATTGGGGGCCTAACCTTAACAGGACATATTATATCGGGGTAGAACTGGGTGGTCCAATGAGTGCAGACTA
TGTTAATACAGAAGAATTCAGGAAGCTCCTTGGCGGGAAGAATCATGTTGCTATTGGATTTGTTGGAAGACAGACAGATA
TTGCACCGGAATTTGGTATGGCAATGAGAGAAAAGAGAGTTTTTTCTACTATACATTGCATAGTCGGAACACAGAACAAT
GTTAAGGGAATATTTACAATAGACCGTTGTAAGGAATCGTCACAGTGGGCTGAGTATGAAATAGAAATGGCTGTGGTAGC
AGCTTCTCTTATTAATATTATTGCTGAGTCTGAAAATAATTAA

Upstream 100 bases:

>100_bases
TTAGAACACTTGTAAAATCGTCATGTATATAATATAATTTTATTATCAAAATTCGGAATTAGTTATTAAGAATTAATAGT
AAATAGCATGAGGTACCAAC

Downstream 100 bases:

>100_bases
TTAATATATTTTATTACAAGATATTGTGTTTTTGATTGACTTGCAAGCCTATATGTTGTATAATCAAATCTGCTTGGGAA
ACCGCATGGATACTGGGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MDNKATEKEKFEIVHKMSRRIASVDKYCVVSVSNKAFEEYFGRIVDTLLEVVAPQDKERLIDFIENYDGTAKSGMFKFIN
AQGEERYNHLFVYQQRGAGNGHMRDIEIVDVESIEEANKSLRDDVSKHKMLLGLDREYTFTYNRDNNIFSMYRYDVDSRD
IIYKADIDDWKRQMLTEGYIEKSDKEMFTNFISEVRSYTQTFSTKFKTSMRTYNKVMETLRFIGTVMTKSDGRKIVVGRV
IPEADNRSYNQISDMIEELQFDSLTHVYNKKTITAYAVKCLKEEKNNRVTIAVLDVDHFKKVNDVYGHMYGDKILARVGR
KLKEVVGEDGVVGRIGGDEFIIVFNGINDEHALRGMLRAIRTQIKWEFVDDFEDLMITCSIGASYSPNNGTEYEELFKKA
DYCLYVAKEKGRDRYVFFRDDLHKESYENSLNTKDKNVNDGREMKELRFLSGIMEEFAQDGRKAVDELLHHMYDSFKLDS
INLYWGPNLNRTYYIGVELGGPMSADYVNTEEFRKLLGGKNHVAIGFVGRQTDIAPEFGMAMREKRVFSTIHCIVGTQNN
VKGIFTIDRCKESSQWAEYEIEMAVVAASLINIIAESENN

Sequences:

>Translated_600_residues
MDNKATEKEKFEIVHKMSRRIASVDKYCVVSVSNKAFEEYFGRIVDTLLEVVAPQDKERLIDFIENYDGTAKSGMFKFIN
AQGEERYNHLFVYQQRGAGNGHMRDIEIVDVESIEEANKSLRDDVSKHKMLLGLDREYTFTYNRDNNIFSMYRYDVDSRD
IIYKADIDDWKRQMLTEGYIEKSDKEMFTNFISEVRSYTQTFSTKFKTSMRTYNKVMETLRFIGTVMTKSDGRKIVVGRV
IPEADNRSYNQISDMIEELQFDSLTHVYNKKTITAYAVKCLKEEKNNRVTIAVLDVDHFKKVNDVYGHMYGDKILARVGR
KLKEVVGEDGVVGRIGGDEFIIVFNGINDEHALRGMLRAIRTQIKWEFVDDFEDLMITCSIGASYSPNNGTEYEELFKKA
DYCLYVAKEKGRDRYVFFRDDLHKESYENSLNTKDKNVNDGREMKELRFLSGIMEEFAQDGRKAVDELLHHMYDSFKLDS
INLYWGPNLNRTYYIGVELGGPMSADYVNTEEFRKLLGGKNHVAIGFVGRQTDIAPEFGMAMREKRVFSTIHCIVGTQNN
VKGIFTIDRCKESSQWAEYEIEMAVVAASLINIIAESENN
>Mature_600_residues
MDNKATEKEKFEIVHKMSRRIASVDKYCVVSVSNKAFEEYFGRIVDTLLEVVAPQDKERLIDFIENYDGTAKSGMFKFIN
AQGEERYNHLFVYQQRGAGNGHMRDIEIVDVESIEEANKSLRDDVSKHKMLLGLDREYTFTYNRDNNIFSMYRYDVDSRD
IIYKADIDDWKRQMLTEGYIEKSDKEMFTNFISEVRSYTQTFSTKFKTSMRTYNKVMETLRFIGTVMTKSDGRKIVVGRV
IPEADNRSYNQISDMIEELQFDSLTHVYNKKTITAYAVKCLKEEKNNRVTIAVLDVDHFKKVNDVYGHMYGDKILARVGR
KLKEVVGEDGVVGRIGGDEFIIVFNGINDEHALRGMLRAIRTQIKWEFVDDFEDLMITCSIGASYSPNNGTEYEELFKKA
DYCLYVAKEKGRDRYVFFRDDLHKESYENSLNTKDKNVNDGREMKELRFLSGIMEEFAQDGRKAVDELLHHMYDSFKLDS
INLYWGPNLNRTYYIGVELGGPMSADYVNTEEFRKLLGGKNHVAIGFVGRQTDIAPEFGMAMREKRVFSTIHCIVGTQNN
VKGIFTIDRCKESSQWAEYEIEMAVVAASLINIIAESENN

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=31.7365269461078, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=32.4324324324324, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786584, Length=159, Percent_Identity=32.0754716981132, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=31.5151515151515, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=31.4465408805031, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=174, Percent_Identity=30.4597701149425, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081881, Length=127, Percent_Identity=32.2834645669291, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788381, Length=200, Percent_Identity=25.5, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=28.9308176100629, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=186, Percent_Identity=26.8817204301075, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787056, Length=125, Percent_Identity=33.6, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 69512; Mature: 69512

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKATEKEKFEIVHKMSRRIASVDKYCVVSVSNKAFEEYFGRIVDTLLEVVAPQDKERL
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHH
IDFIENYDGTAKSGMFKFINAQGEERYNHLFVYQQRGAGNGHMRDIEIVDVESIEEANKS
HHHHHCCCCCCCCCHHHEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEHHHHHHHHHH
LRDDVSKHKMLLGLDREYTFTYNRDNNIFSMYRYDVDSRDIIYKADIDDWKRQMLTEGYI
HHHHHHHHHHHEECCCCEEEEECCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHH
EKSDKEMFTNFISEVRSYTQTFSTKFKTSMRTYNKVMETLRFIGTVMTKSDGRKIVVGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
IPEADNRSYNQISDMIEELQFDSLTHVYNKKTITAYAVKCLKEEKNNRVTIAVLDVDHFK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEHHHHH
KVNDVYGHMYGDKILARVGRKLKEVVGEDGVVGRIGGDEFIIVFNGINDEHALRGMLRAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHH
RTQIKWEFVDDFEDLMITCSIGASYSPNNGTEYEELFKKADYCLYVAKEKGRDRYVFFRD
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCEEEEECC
DLHKESYENSLNTKDKNVNDGREMKELRFLSGIMEEFAQDGRKAVDELLHHMYDSFKLDS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
INLYWGPNLNRTYYIGVELGGPMSADYVNTEEFRKLLGGKNHVAIGFVGRQTDIAPEFGM
EEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
AMREKRVFSTIHCIVGTQNNVKGIFTIDRCKESSQWAEYEIEMAVVAASLINIIAESENN
HHHHHHHHHHHHHEECCCCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNKATEKEKFEIVHKMSRRIASVDKYCVVSVSNKAFEEYFGRIVDTLLEVVAPQDKERL
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHH
IDFIENYDGTAKSGMFKFINAQGEERYNHLFVYQQRGAGNGHMRDIEIVDVESIEEANKS
HHHHHCCCCCCCCCHHHEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEHHHHHHHHHH
LRDDVSKHKMLLGLDREYTFTYNRDNNIFSMYRYDVDSRDIIYKADIDDWKRQMLTEGYI
HHHHHHHHHHHEECCCCEEEEECCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHH
EKSDKEMFTNFISEVRSYTQTFSTKFKTSMRTYNKVMETLRFIGTVMTKSDGRKIVVGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
IPEADNRSYNQISDMIEELQFDSLTHVYNKKTITAYAVKCLKEEKNNRVTIAVLDVDHFK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEHHHHH
KVNDVYGHMYGDKILARVGRKLKEVVGEDGVVGRIGGDEFIIVFNGINDEHALRGMLRAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHH
RTQIKWEFVDDFEDLMITCSIGASYSPNNGTEYEELFKKADYCLYVAKEKGRDRYVFFRD
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCCEEEEECC
DLHKESYENSLNTKDKNVNDGREMKELRFLSGIMEEFAQDGRKAVDELLHHMYDSFKLDS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
INLYWGPNLNRTYYIGVELGGPMSADYVNTEEFRKLLGGKNHVAIGFVGRQTDIAPEFGM
EEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
AMREKRVFSTIHCIVGTQNNVKGIFTIDRCKESSQWAEYEIEMAVVAASLINIIAESENN
HHHHHHHHHHHHHEECCCCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]