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The map label for this gene is ygcA [C]

Identifier: 238917477

GI number: 238917477

Start: 1604893

End: 1606305

Strand: Reverse

Name: ygcA [C]

Synonym: EUBELI_01555

Alternate gene names: 238917477

Gene position: 1606305-1604893 (Counterclockwise)

Preceding gene: 238917478

Following gene: 238917476

Centisome position: 74.91

GC content: 43.52

Gene sequence:

>1413_bases
ATGTGCGGAATGGAGTATAGATTGAAAAAAGGAAGCGTATACGAAGGTAAAGTTGAAAAGGTTGATTTCCCTAACAAGGC
GACAGTGTGGGTGACAGATGAGGACGGACAGAAGGAAAAGGCAATCGTCAAGAACGCAATTCCTGGACAGACTGTCAGAT
TCTGCGTGAATAAGAAAAGAAAGGGACATTGCGAAGGCAGACTTATGGAAGTTGTTGAGAAGAGTCCGCTTGAAACCAAC
CCGGCATGTCCACATTTTGGCAAATGCGGTGGCTGCACTTACCAGACAGTAGCTTACGAGGAACAGTTAAAGATTAAGAG
CACACAGGTGGAAAAGCTTCTTAGAGAAGTTGTTTCGGGTGAGCTTCCATTTGAGGGGATAATCGGAAGTCCGGTTACAG
AAGAATACCGTAATAAGATGGAATTTTCATTTGGCGATGAGTACAAGGACGGACCTCTTGCACTCGGACTTCACAAACGA
AACAGCATGTATGATATTGTTCCAGTTACAGAATGTAAGATTATTGATGAGGATTACAGAAAGATTCTCACATGCGTTCA
GGATTATGCAATAGAGAAGGAGCTTCCTTTCCAGCACAAGTTAAGCCACGAGGGATATCTGCGTCATCTTCTTGTAAGAA
AGTCAGTAAAGACAGGACAGATTCTTGTTGATATTGTTACAACAACTCAGATTGAGCATGATTTCACAGAGCTTGTAAAC
CGCCTGACATCAATTGAATATAAGGGCACTCTTACAGGTGTTCTCCATACATTTAACGACAGCCTTGCAGATGCAGTAAT
TAACGAGAAAACTGAGCTTCTGTATGGTCATGATTATATTGAGGAGGAACTTCTTGGACTGCGTTTCAAGATAACTCCGT
TCTCATTCTTCCAGACTAATTCTCTTGGAGCGGAAGTGCTTTACTCTAAGGCGAGGGAGTATGTGCTTTCTGGCGGATTT
GGAGATGTGGCTGACAGCAAACCGGTTATATATGACCTGTATACAGGTACTGGTACGATCGCACAGATGTTATCTCCGGT
TGCCAGCAAGGTTATCGGTGTTGAGATTGTTGCGGAAGCTGTTGAGGCTGCTAAGAAGAATGCAGCCCAGAACGGTCTTA
CTAATTGTGAGTTCATTGCAGATGATGTCTTAAAGGCGCTTGATAATATTGAGATTAAGCCTGATTTCATCGTACTTGAC
CCACCTCGTGACGGAATTCACCCTAAGGCGCTTGAGAAGATTATTGACTACGGTGTTGACAGAATGGTGTACATATCATG
TAAGCCTACTTCGCTTGCAAGAGACCTTGTTACTCTGCAGGAGAGAGGGTATAAGGTGGAGAAGTGCTGTTGCGTGGATA
TGTTTCCTAATACGGGGCATGTTGAGTCGGTATGTTTGCTGTCAAGGAAATAA

Upstream 100 bases:

>100_bases
TATACTTTAGCACATTTTTCTGATAAAATTATATAAGGTATGCCGTTATGTGAATAAGTGCTGCCAGAAACTATTAATAT
GTTAATAACAGGCACAATTC

Downstream 100 bases:

>100_bases
AATCAAGTGCTGAAAAGTGGCGTATTTCCGGGCTTTTTCGGAAGTTGGGATATAAAGCCTAACCTCTGAAAAAGCTCGGT
TTTCTTATATGGAAACATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MCGMEYRLKKGSVYEGKVEKVDFPNKATVWVTDEDGQKEKAIVKNAIPGQTVRFCVNKKRKGHCEGRLMEVVEKSPLETN
PACPHFGKCGGCTYQTVAYEEQLKIKSTQVEKLLREVVSGELPFEGIIGSPVTEEYRNKMEFSFGDEYKDGPLALGLHKR
NSMYDIVPVTECKIIDEDYRKILTCVQDYAIEKELPFQHKLSHEGYLRHLLVRKSVKTGQILVDIVTTTQIEHDFTELVN
RLTSIEYKGTLTGVLHTFNDSLADAVINEKTELLYGHDYIEEELLGLRFKITPFSFFQTNSLGAEVLYSKAREYVLSGGF
GDVADSKPVIYDLYTGTGTIAQMLSPVASKVIGVEIVAEAVEAAKKNAAQNGLTNCEFIADDVLKALDNIEIKPDFIVLD
PPRDGIHPKALEKIIDYGVDRMVYISCKPTSLARDLVTLQERGYKVEKCCCVDMFPNTGHVESVCLLSRK

Sequences:

>Translated_470_residues
MCGMEYRLKKGSVYEGKVEKVDFPNKATVWVTDEDGQKEKAIVKNAIPGQTVRFCVNKKRKGHCEGRLMEVVEKSPLETN
PACPHFGKCGGCTYQTVAYEEQLKIKSTQVEKLLREVVSGELPFEGIIGSPVTEEYRNKMEFSFGDEYKDGPLALGLHKR
NSMYDIVPVTECKIIDEDYRKILTCVQDYAIEKELPFQHKLSHEGYLRHLLVRKSVKTGQILVDIVTTTQIEHDFTELVN
RLTSIEYKGTLTGVLHTFNDSLADAVINEKTELLYGHDYIEEELLGLRFKITPFSFFQTNSLGAEVLYSKAREYVLSGGF
GDVADSKPVIYDLYTGTGTIAQMLSPVASKVIGVEIVAEAVEAAKKNAAQNGLTNCEFIADDVLKALDNIEIKPDFIVLD
PPRDGIHPKALEKIIDYGVDRMVYISCKPTSLARDLVTLQERGYKVEKCCCVDMFPNTGHVESVCLLSRK
>Mature_470_residues
MCGMEYRLKKGSVYEGKVEKVDFPNKATVWVTDEDGQKEKAIVKNAIPGQTVRFCVNKKRKGHCEGRLMEVVEKSPLETN
PACPHFGKCGGCTYQTVAYEEQLKIKSTQVEKLLREVVSGELPFEGIIGSPVTEEYRNKMEFSFGDEYKDGPLALGLHKR
NSMYDIVPVTECKIIDEDYRKILTCVQDYAIEKELPFQHKLSHEGYLRHLLVRKSVKTGQILVDIVTTTQIEHDFTELVN
RLTSIEYKGTLTGVLHTFNDSLADAVINEKTELLYGHDYIEEELLGLRFKITPFSFFQTNSLGAEVLYSKAREYVLSGGF
GDVADSKPVIYDLYTGTGTIAQMLSPVASKVIGVEIVAEAVEAAKKNAAQNGLTNCEFIADDVLKALDNIEIKPDFIVLD
PPRDGIHPKALEKIIDYGVDRMVYISCKPTSLARDLVTLQERGYKVEKCCCVDMFPNTGHVESVCLLSRK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI269784680, Length=425, Percent_Identity=29.1764705882353, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI269784676, Length=425, Percent_Identity=29.1764705882353, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI20149688, Length=425, Percent_Identity=29.1764705882353, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI34222389, Length=420, Percent_Identity=28.0952380952381, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI51173878, Length=420, Percent_Identity=28.0952380952381, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI269784678, Length=369, Percent_Identity=28.4552845528455, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1789148, Length=430, Percent_Identity=27.906976744186, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1787083, Length=394, Percent_Identity=24.6192893401015, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790403, Length=220, Percent_Identity=30, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71997438, Length=500, Percent_Identity=25.6, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322909, Length=416, Percent_Identity=25, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24666579, Length=426, Percent_Identity=30.9859154929577, Blast_Score=152, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 52711; Mature: 52711

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGMEYRLKKGSVYEGKVEKVDFPNKATVWVTDEDGQKEKAIVKNAIPGQTVRFCVNKKR
CCCCCCEECCCCEECCCEEEECCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHCCCC
KGHCEGRLMEVVEKSPLETNPACPHFGKCGGCTYQTVAYEEQLKIKSTQVEKLLREVVSG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
ELPFEGIIGSPVTEEYRNKMEFSFGDEYKDGPLALGLHKRNSMYDIVPVTECKIIDEDYR
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEECHHHHH
KILTCVQDYAIEKELPFQHKLSHEGYLRHLLVRKSVKTGQILVDIVTTTQIEHDFTELVN
HHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHH
RLTSIEYKGTLTGVLHTFNDSLADAVINEKTELLYGHDYIEEELLGLRFKITPFSFFQTN
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHCCEEEECCEEEEECC
SLGAEVLYSKAREYVLSGGFGDVADSKPVIYDLYTGTGTIAQMLSPVASKVIGVEIVAEA
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VEAAKKNAAQNGLTNCEFIADDVLKALDNIEIKPDFIVLDPPRDGIHPKALEKIIDYGVD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCC
RMVYISCKPTSLARDLVTLQERGYKVEKCCCVDMFPNTGHVESVCLLSRK
EEEEEEECCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHEEEECCC
>Mature Secondary Structure
MCGMEYRLKKGSVYEGKVEKVDFPNKATVWVTDEDGQKEKAIVKNAIPGQTVRFCVNKKR
CCCCCCEECCCCEECCCEEEECCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHCCCC
KGHCEGRLMEVVEKSPLETNPACPHFGKCGGCTYQTVAYEEQLKIKSTQVEKLLREVVSG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
ELPFEGIIGSPVTEEYRNKMEFSFGDEYKDGPLALGLHKRNSMYDIVPVTECKIIDEDYR
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEECHHHHH
KILTCVQDYAIEKELPFQHKLSHEGYLRHLLVRKSVKTGQILVDIVTTTQIEHDFTELVN
HHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHH
RLTSIEYKGTLTGVLHTFNDSLADAVINEKTELLYGHDYIEEELLGLRFKITPFSFFQTN
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHCCEEEECCEEEEECC
SLGAEVLYSKAREYVLSGGFGDVADSKPVIYDLYTGTGTIAQMLSPVASKVIGVEIVAEA
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VEAAKKNAAQNGLTNCEFIADDVLKALDNIEIKPDFIVLDPPRDGIHPKALEKIIDYGVD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCC
RMVYISCKPTSLARDLVTLQERGYKVEKCCCVDMFPNTGHVESVCLLSRK
EEEEEEECCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]