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The map label for this gene is lepB [H]

Identifier: 238917248

GI number: 238917248

Start: 1359607

End: 1360356

Strand: Direct

Name: lepB [H]

Synonym: EUBELI_01322

Alternate gene names: 238917248

Gene position: 1359607-1360356 (Clockwise)

Preceding gene: 238917247

Following gene: 238917249

Centisome position: 63.41

GC content: 33.87

Gene sequence:

>750_bases
ATGACAGATTATAAAAATAATGAATTCGACGATGATAAAACATCAAAATACGATTTTGATGATGGCATAGAATTTCTTGA
TGATACTTATGAGCATCATGACAATGATTATTTTTCAGATTATGATGATAATGCTTCATACGAAACAGATATTCCGCGCT
ACAATGAAGAATACTATAATGACACTAAGGATTCCCAGAAGCAGGCTGCTAAAACCAGTGTTGGTTCTGAAATCTTTAGT
TTCTTAAAAATCCTGACATTGGCTATTATCATGGCATTTCTATTTACAAGATTTATCATTGTTAATGCCCAGGTACCTTC
TGGTTCTATGGAGAATACTATTCTCACAGGTGACAGACTTATAGGTTTCAGACTCGCCTACCTTTTCAGTGAGCCTAAGC
GCGGAGATATTGTAATATTCAAATATCCTGATGACGAATCTCAGAATTTCGTTAAACGGGTAATAGGAGTCCCTGGTGAT
GTAATACAGATTACCAATGGGCATGTATATGTGAATGGTGATATTCTTGAAGAAGATTATTTAAGAGAACCTATGTATAA
TGATGGTGATGAGCTAACCTATGTTGTACCTGCTGATTCATATTTTATGCTCGGAGATAACAGAAATAATTCCAAGGATT
CCAGATATTGGACCAACACATTTGTATCAAAAGATAAGATTATTGCTAAGGTTTCTTTCAGATATTTCAATGTCAGAACG
AAGCGTTTTACATTTTCTTTCATTAAATAA

Upstream 100 bases:

>100_bases
GACAGGATTCATTGCAAGAAGTAATAAAATCATGGAATTGCTTGCAAAATAACGCCTTTTAAACTATCATTGTCTTATAT
AAAGATAAGGACTATTTAAT

Downstream 100 bases:

>100_bases
CACTCTGAATAAAGAATAATATAAAGGGTACAATAATATGGCCGCTATGTTTCACAAACAATAGCGGTCATATTTGTTTT
TTGAAAGGAGAAATGCTATG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTDYKNNEFDDDKTSKYDFDDGIEFLDDTYEHHDNDYFSDYDDNASYETDIPRYNEEYYNDTKDSQKQAAKTSVGSEIFS
FLKILTLAIIMAFLFTRFIIVNAQVPSGSMENTILTGDRLIGFRLAYLFSEPKRGDIVIFKYPDDESQNFVKRVIGVPGD
VIQITNGHVYVNGDILEEDYLREPMYNDGDELTYVVPADSYFMLGDNRNNSKDSRYWTNTFVSKDKIIAKVSFRYFNVRT
KRFTFSFIK

Sequences:

>Translated_249_residues
MTDYKNNEFDDDKTSKYDFDDGIEFLDDTYEHHDNDYFSDYDDNASYETDIPRYNEEYYNDTKDSQKQAAKTSVGSEIFS
FLKILTLAIIMAFLFTRFIIVNAQVPSGSMENTILTGDRLIGFRLAYLFSEPKRGDIVIFKYPDDESQNFVKRVIGVPGD
VIQITNGHVYVNGDILEEDYLREPMYNDGDELTYVVPADSYFMLGDNRNNSKDSRYWTNTFVSKDKIIAKVSFRYFNVRT
KRFTFSFIK
>Mature_248_residues
TDYKNNEFDDDKTSKYDFDDGIEFLDDTYEHHDNDYFSDYDDNASYETDIPRYNEEYYNDTKDSQKQAAKTSVGSEIFSF
LKILTLAIIMAFLFTRFIIVNAQVPSGSMENTILTGDRLIGFRLAYLFSEPKRGDIVIFKYPDDESQNFVKRVIGVPGDV
IQITNGHVYVNGDILEEDYLREPMYNDGDELTYVVPADSYFMLGDNRNNSKDSRYWTNTFVSKDKIIAKVSFRYFNVRTK
RFTFSFIK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=100, Percent_Identity=37, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29128; Mature: 28997

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYKNNEFDDDKTSKYDFDDGIEFLDDTYEHHDNDYFSDYDDNASYETDIPRYNEEYYN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHC
DTKDSQKQAAKTSVGSEIFSFLKILTLAIIMAFLFTRFIIVNAQVPSGSMENTILTGDRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCHH
IGFRLAYLFSEPKRGDIVIFKYPDDESQNFVKRVIGVPGDVIQITNGHVYVNGDILEEDY
HHHHHEEHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCEEEEECCEECHHH
LREPMYNDGDELTYVVPADSYFMLGDNRNNSKDSRYWTNTFVSKDKIIAKVSFRYFNVRT
HCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEEEEEEEEE
KRFTFSFIK
EEEEEEECC
>Mature Secondary Structure 
TDYKNNEFDDDKTSKYDFDDGIEFLDDTYEHHDNDYFSDYDDNASYETDIPRYNEEYYN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHC
DTKDSQKQAAKTSVGSEIFSFLKILTLAIIMAFLFTRFIIVNAQVPSGSMENTILTGDRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCHH
IGFRLAYLFSEPKRGDIVIFKYPDDESQNFVKRVIGVPGDVIQITNGHVYVNGDILEEDY
HHHHHEEHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCEEEEECCEECHHH
LREPMYNDGDELTYVVPADSYFMLGDNRNNSKDSRYWTNTFVSKDKIIAKVSFRYFNVRT
HCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEEEEEEEEEEE
KRFTFSFIK
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]