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The map label for this gene is htpG [H]

Identifier: 238917247

GI number: 238917247

Start: 1357564

End: 1359558

Strand: Direct

Name: htpG [H]

Synonym: EUBELI_01321

Alternate gene names: 238917247

Gene position: 1357564-1359558 (Clockwise)

Preceding gene: 238917246

Following gene: 238917248

Centisome position: 63.31

GC content: 36.14

Gene sequence:

>1995_bases
ATGTCAAAAGAACATGGTAATTTATCTATTAACAGCCAGAATATTTTCCCTATCATCAAGAAATGGATGTATTCTGACCA
TGATATCTTCTATAGAGAGTTAGTTTCTAATGCATGTGATGCTATCACTAAGCTCAAGAAGCTTTCAATGATTGGGGAGT
ATGAAGCTCCTGATGATATTGAATATAAGGTTGAAATTAAGCTTTCTGCAAAAGATAAGACCATTAAAATCATTGATAAC
GGTATCGGTATGACTAAGGAAGAGGTTGATGAGTATATCAACCAGATTGCTTTTTCAGGTGCTGAAGCATTCCTTGAGAA
GTATAAGGATAAGGCTAACGATGACCAGATTATCGGACATTTTGGTTTAGGTTTCTACTCAGCATTTATGGTTGCTGACC
AGGTTACTATTGATACTCTTTCATTTAAGGACGGAGCAGAATCAGTTCACTGGTCATGTGACGGAGGAACTGAATATGAT
ATAAGTGAGGGAACCAAAACAACTCCTGGCACTGAGATTACTCTTTACCTCAATGAGGACAGCTATGAATTTGCCAACGA
ATATAAGGCTAAAGAAGTTCTTGATAAGTACTGCTCTTTCATGCCGGTTCCAATCTTTGTAACTAACGAAGATGCGGGTG
AACAGACTGAGGAAATTCCTGAAGAAGAAGTTACAGAAAAAGATACAGTTCTTGATACATTTATAAAGGACGCTGTTACA
GAAGAAGTTGAGAAAGAAGATGGGACTAAGGAAACTGTTGAGAAAGTTCCAGCCAAAAAGATGGCTAAGATTGTAAAAAG
ACCTGTTGCAATCAACGATATCCATCCACTCTGGACAAAGCATCCTAATGAATGTTCAGATGAAGATTACAAGGAATTCT
ACCGCAAGGTATTCCACGATTATAAAGAACCATTATTCTGGATTCACCTTAATATGGATTATCCTTTCAATCTTAAGGGT
ATTCTCTACTTCCCTAAGATTAATACAGAGTATGAATCTATTGAAGGTACTATAAAGCTTTATAACAATCAGGTATTCGT
AGCAGATAACATCAAAGAAGTTATTCCAGAATTTTTACTTCTTCTTAAAGGTGTTATTGACTGCCCAGACCTTCCACTTA
ATGTATCACGTTCAGCACTTCAGAATGATGGATTTGTTAAGAAGATATCTGATTACATTACTAAAAAGGTTGCCGACAAG
CTTTCAGGAATGTGTAAAACAGATAAAGAGAACTATGAGAAATACTGGGATGACATCAATCCATTTATTAAATTCGGCTG
CTTAAAGGATGAGAAATTTGCAGAGAAGATGAATGATTACATCATATTCAAGAACCTTGATGGCAAATATTTGACTCTTA
AGGAATGTCTCGAAGAGAATAAAGAAAAACACGAAAACACTGTATTCTATGTAACAGATGAAGTTGAACAGAGTCAGTAT
ATCAACATGTTTAAGAACGAAGGAATTGATGCTGTAATTCTTACTCATAACATTGACCAGCCATTCATAACTAACATGGA
ATCCAAGAATGAAAATCTCAAGTTCAAGCGTATCGATGCAGATCTTTCAGACAGCTTTAAGGAAGAGACTTCTAAAGACG
AGTTGAAGGACATGACTGAAAAGCTCTCTAAGACTTTCAAGGATGCTCTTGGCAAAGAAAATTTAACTGTTAATGTCGAG
AAATTAAATGATTCATCTATATCTTCAATGATTACTCTTTCAGAAGAAAGCAGACGTATGCAGGATATGATGAAAATGTA
CGGTATGGCAGGTATGGACCCTAATATGTTTGGTGCTGAGGGTCAGACTCTTGTACTTAATGCTAACAATGACCTTGTCA
AATATGTTGCAGAACATGCAGACGGTGAAAATACTAAGATTATATGTGAACAGCTCTATGACCTTGCAATGCTCAGTCAT
GCGCCTCTTTCACCAGAGCAGATGACAGGATTCATTGCAAGAAGTAATAAAATCATGGAATTGCTTGCAAAATAA

Upstream 100 bases:

>100_bases
ACTCTTATTTAAGGAGTGCTAATTTTTGCTTGACTTATGTTTTATTGTGTATTAAATTAACATTTAGTTTAATACTATAC
AGATTGGAGAGTGAAATATT

Downstream 100 bases:

>100_bases
CGCCTTTTAAACTATCATTGTCTTATATAAAGATAAGGACTATTTAATATGACAGATTATAAAAATAATGAATTCGACGA
TGATAAAACATCAAAATACG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSKEHGNLSINSQNIFPIIKKWMYSDHDIFYRELVSNACDAITKLKKLSMIGEYEAPDDIEYKVEIKLSAKDKTIKIIDN
GIGMTKEEVDEYINQIAFSGAEAFLEKYKDKANDDQIIGHFGLGFYSAFMVADQVTIDTLSFKDGAESVHWSCDGGTEYD
ISEGTKTTPGTEITLYLNEDSYEFANEYKAKEVLDKYCSFMPVPIFVTNEDAGEQTEEIPEEEVTEKDTVLDTFIKDAVT
EEVEKEDGTKETVEKVPAKKMAKIVKRPVAINDIHPLWTKHPNECSDEDYKEFYRKVFHDYKEPLFWIHLNMDYPFNLKG
ILYFPKINTEYESIEGTIKLYNNQVFVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSALQNDGFVKKISDYITKKVADK
LSGMCKTDKENYEKYWDDINPFIKFGCLKDEKFAEKMNDYIIFKNLDGKYLTLKECLEENKEKHENTVFYVTDEVEQSQY
INMFKNEGIDAVILTHNIDQPFITNMESKNENLKFKRIDADLSDSFKEETSKDELKDMTEKLSKTFKDALGKENLTVNVE
KLNDSSISSMITLSEESRRMQDMMKMYGMAGMDPNMFGAEGQTLVLNANNDLVKYVAEHADGENTKIICEQLYDLAMLSH
APLSPEQMTGFIARSNKIMELLAK

Sequences:

>Translated_664_residues
MSKEHGNLSINSQNIFPIIKKWMYSDHDIFYRELVSNACDAITKLKKLSMIGEYEAPDDIEYKVEIKLSAKDKTIKIIDN
GIGMTKEEVDEYINQIAFSGAEAFLEKYKDKANDDQIIGHFGLGFYSAFMVADQVTIDTLSFKDGAESVHWSCDGGTEYD
ISEGTKTTPGTEITLYLNEDSYEFANEYKAKEVLDKYCSFMPVPIFVTNEDAGEQTEEIPEEEVTEKDTVLDTFIKDAVT
EEVEKEDGTKETVEKVPAKKMAKIVKRPVAINDIHPLWTKHPNECSDEDYKEFYRKVFHDYKEPLFWIHLNMDYPFNLKG
ILYFPKINTEYESIEGTIKLYNNQVFVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSALQNDGFVKKISDYITKKVADK
LSGMCKTDKENYEKYWDDINPFIKFGCLKDEKFAEKMNDYIIFKNLDGKYLTLKECLEENKEKHENTVFYVTDEVEQSQY
INMFKNEGIDAVILTHNIDQPFITNMESKNENLKFKRIDADLSDSFKEETSKDELKDMTEKLSKTFKDALGKENLTVNVE
KLNDSSISSMITLSEESRRMQDMMKMYGMAGMDPNMFGAEGQTLVLNANNDLVKYVAEHADGENTKIICEQLYDLAMLSH
APLSPEQMTGFIARSNKIMELLAK
>Mature_663_residues
SKEHGNLSINSQNIFPIIKKWMYSDHDIFYRELVSNACDAITKLKKLSMIGEYEAPDDIEYKVEIKLSAKDKTIKIIDNG
IGMTKEEVDEYINQIAFSGAEAFLEKYKDKANDDQIIGHFGLGFYSAFMVADQVTIDTLSFKDGAESVHWSCDGGTEYDI
SEGTKTTPGTEITLYLNEDSYEFANEYKAKEVLDKYCSFMPVPIFVTNEDAGEQTEEIPEEEVTEKDTVLDTFIKDAVTE
EVEKEDGTKETVEKVPAKKMAKIVKRPVAINDIHPLWTKHPNECSDEDYKEFYRKVFHDYKEPLFWIHLNMDYPFNLKGI
LYFPKINTEYESIEGTIKLYNNQVFVADNIKEVIPEFLLLLKGVIDCPDLPLNVSRSALQNDGFVKKISDYITKKVADKL
SGMCKTDKENYEKYWDDINPFIKFGCLKDEKFAEKMNDYIIFKNLDGKYLTLKECLEENKEKHENTVFYVTDEVEQSQYI
NMFKNEGIDAVILTHNIDQPFITNMESKNENLKFKRIDADLSDSFKEETSKDELKDMTEKLSKTFKDALGKENLTVNVEK
LNDSSISSMITLSEESRRMQDMMKMYGMAGMDPNMFGAEGQTLVLNANNDLVKYVAEHADGENTKIICEQLYDLAMLSHA
PLSPEQMTGFIARSNKIMELLAK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI154146191, Length=506, Percent_Identity=29.6442687747036, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI153792590, Length=506, Percent_Identity=29.6442687747036, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI20149594, Length=503, Percent_Identity=30.2186878727634, Blast_Score=216, Evalue=6e-56,
Organism=Homo sapiens, GI155722983, Length=197, Percent_Identity=36.5482233502538, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI4507677, Length=193, Percent_Identity=35.2331606217617, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1786679, Length=672, Percent_Identity=29.0178571428571, Blast_Score=259, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17542208, Length=670, Percent_Identity=28.5074626865672, Blast_Score=225, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17559162, Length=502, Percent_Identity=29.8804780876494, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI115535205, Length=698, Percent_Identity=24.785100286533, Blast_Score=186, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI115535167, Length=453, Percent_Identity=28.0353200883002, Blast_Score=182, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6325016, Length=682, Percent_Identity=27.5659824046921, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6323840, Length=684, Percent_Identity=27.1929824561404, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21357739, Length=557, Percent_Identity=32.3159784560144, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI17647529, Length=654, Percent_Identity=28.2874617737003, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24586016, Length=213, Percent_Identity=38.0281690140845, Blast_Score=144, Evalue=3e-34,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 76275; Mature: 76144

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEHGNLSINSQNIFPIIKKWMYSDHDIFYRELVSNACDAITKLKKLSMIGEYEAPDDI
CCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EYKVEIKLSAKDKTIKIIDNGIGMTKEEVDEYINQIAFSGAEAFLEKYKDKANDDQIIGH
EEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEH
FGLGFYSAFMVADQVTIDTLSFKDGAESVHWSCDGGTEYDISEGTKTTPGTEITLYLNED
HHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCEECCCCCCCCCCCCEEEEEECCC
SYEFANEYKAKEVLDKYCSFMPVPIFVTNEDAGEQTEEIPEEEVTEKDTVLDTFIKDAVT
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
EEVEKEDGTKETVEKVPAKKMAKIVKRPVAINDIHPLWTKHPNECSDEDYKEFYRKVFHD
HHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHH
YKEPLFWIHLNMDYPFNLKGILYFPKINTEYESIEGTIKLYNNQVFVADNIKEVIPEFLL
HCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHCCCEEEEECCEEEEECCHHHHHHHHHH
LLKGVIDCPDLPLNVSRSALQNDGFVKKISDYITKKVADKLSGMCKTDKENYEKYWDDIN
HHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PFIKFGCLKDEKFAEKMNDYIIFKNLDGKYLTLKECLEENKEKHENTVFYVTDEVEQSQY
HHHHHCCCCCHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCEEEEEECCHHHHHH
INMFKNEGIDAVILTHNIDQPFITNMESKNENLKFKRIDADLSDSFKEETSKDELKDMTE
HHHHHCCCCCEEEEEECCCCCHHCCCCCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHH
KLSKTFKDALGKENLTVNVEKLNDSSISSMITLSEESRRMQDMMKMYGMAGMDPNMFGAE
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECHHHHHHHHHHHHHCCCCCCCCCCCCC
GQTLVLNANNDLVKYVAEHADGENTKIICEQLYDLAMLSHAPLSPEQMTGFIARSNKIME
CCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLAK
HHCC
>Mature Secondary Structure 
SKEHGNLSINSQNIFPIIKKWMYSDHDIFYRELVSNACDAITKLKKLSMIGEYEAPDDI
CCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EYKVEIKLSAKDKTIKIIDNGIGMTKEEVDEYINQIAFSGAEAFLEKYKDKANDDQIIGH
EEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEH
FGLGFYSAFMVADQVTIDTLSFKDGAESVHWSCDGGTEYDISEGTKTTPGTEITLYLNED
HHHHHHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCEECCCCCCCCCCCCEEEEEECCC
SYEFANEYKAKEVLDKYCSFMPVPIFVTNEDAGEQTEEIPEEEVTEKDTVLDTFIKDAVT
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
EEVEKEDGTKETVEKVPAKKMAKIVKRPVAINDIHPLWTKHPNECSDEDYKEFYRKVFHD
HHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHH
YKEPLFWIHLNMDYPFNLKGILYFPKINTEYESIEGTIKLYNNQVFVADNIKEVIPEFLL
HCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHCCCEEEEECCEEEEECCHHHHHHHHHH
LLKGVIDCPDLPLNVSRSALQNDGFVKKISDYITKKVADKLSGMCKTDKENYEKYWDDIN
HHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PFIKFGCLKDEKFAEKMNDYIIFKNLDGKYLTLKECLEENKEKHENTVFYVTDEVEQSQY
HHHHHCCCCCHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCEEEEEECCHHHHHH
INMFKNEGIDAVILTHNIDQPFITNMESKNENLKFKRIDADLSDSFKEETSKDELKDMTE
HHHHHCCCCCEEEEEECCCCCHHCCCCCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHH
KLSKTFKDALGKENLTVNVEKLNDSSISSMITLSEESRRMQDMMKMYGMAGMDPNMFGAE
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECHHHHHHHHHHHHHCCCCCCCCCCCCC
GQTLVLNANNDLVKYVAEHADGENTKIICEQLYDLAMLSHAPLSPEQMTGFIARSNKIME
CCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLAK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]