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The map label for this gene is exbB [H]

Identifier: 238896519

GI number: 238896519

Start: 4498730

End: 4499461

Strand: Reverse

Name: exbB [H]

Synonym: KP1_4704

Alternate gene names: 238896519

Gene position: 4499461-4498730 (Counterclockwise)

Preceding gene: 238896520

Following gene: 238896518

Centisome position: 85.73

GC content: 59.7

Gene sequence:

>732_bases
GTGGGTAATAATTTGATGCAGGCGGATCTCTCCGTTTGGGGTATGTATCATCATGCCGATATTGTCGTTAAGGTGGTGAT
GATTGGCCTGATTCTGGCGTCGGTCGTCACATGGGCCATCTTCTTCGGTAAAGGGGCGGAAATCCTCGCCAGCAAGCGTC
GCCTCAAACGTGAACAGCAGCAGCTGGCGGAAGCCCGCTCTCTCGATCAGGCCAGCGATATCGCCAGCGCCTTTGAGGCG
AAAAGCCTCACCACCCAGCTTATCAATGAAGCGCAGAACGAACTCGAACTCTCTGCCGGTGCCGAAGACAATGAAGGCAT
CAAGGAACGAACCGGTTTTCGCCTTGAGCGCCGCGTTGCGGCGGTTGGTCGCCATATGGGGCGCGGTAACGGCTATCTGG
CGACCATCGGCGCCATTTCCCCGTTTGTGGGCCTGTTTGGTACCGTCTGGGGCATCATGAACAGCTTTATCGGCATCGCC
CAGACCCAGACCACCAATCTTGCGGTGGTAGCGCCGGGCATCGCAGAAGCGCTGCTGGCGACGGCCATCGGCCTGTTCGC
CGCCATCCCGGCGGTGGTCATCTATAACATCTTCGCCCGCATGATCGGCAGCTACAAGGCCTCGCTCGGCGACGTCGCCG
CTCAGGTACTCCTGCTGCAAAGCCGCGATCTGGACCTCAGCGCCAGCGGCGTGAAGCCGGTGCGCAGCGCGCAGAAATTA
CGGGTAGGTTGA

Upstream 100 bases:

>100_bases
TTGCTGCACAGTGTAAATACTAATGAGAACCACTATCAATTCGATGTCGTTTTGATATTATTGTGGGCAGATTTTGTGAT
TATCGTCGTGGAGATAGAGC

Downstream 100 bases:

>100_bases
TCGGCTATGGCGATGCGTCTTAATGAAAACCTGGACGATAACGGCGAAATGCATGAGATCAACGTGACGCCGTTTATCGA
CGTCATGCTGGTTCTGCTGA

Product: biopolymer transport protein ExbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MGNNLMQADLSVWGMYHHADIVVKVVMIGLILASVVTWAIFFGKGAEILASKRRLKREQQQLAEARSLDQASDIASAFEA
KSLTTQLINEAQNELELSAGAEDNEGIKERTGFRLERRVAAVGRHMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
QTQTTNLAVVAPGIAEALLATAIGLFAAIPAVVIYNIFARMIGSYKASLGDVAAQVLLLQSRDLDLSASGVKPVRSAQKL
RVG

Sequences:

>Translated_243_residues
MGNNLMQADLSVWGMYHHADIVVKVVMIGLILASVVTWAIFFGKGAEILASKRRLKREQQQLAEARSLDQASDIASAFEA
KSLTTQLINEAQNELELSAGAEDNEGIKERTGFRLERRVAAVGRHMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
QTQTTNLAVVAPGIAEALLATAIGLFAAIPAVVIYNIFARMIGSYKASLGDVAAQVLLLQSRDLDLSASGVKPVRSAQKL
RVG
>Mature_242_residues
GNNLMQADLSVWGMYHHADIVVKVVMIGLILASVVTWAIFFGKGAEILASKRRLKREQQQLAEARSLDQASDIASAFEAK
SLTTQLINEAQNELELSAGAEDNEGIKERTGFRLERRVAAVGRHMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQ
TQTTNLAVVAPGIAEALLATAIGLFAAIPAVVIYNIFARMIGSYKASLGDVAAQVLLLQSRDLDLSASGVKPVRSAQKLR
VG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=244, Percent_Identity=84.016393442623, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1786958, Length=208, Percent_Identity=33.1730769230769, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25926; Mature: 25795

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNNLMQADLSVWGMYHHADIVVKVVMIGLILASVVTWAIFFGKGAEILASKRRLKREQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QLAEARSLDQASDIASAFEAKSLTTQLINEAQNELELSAGAEDNEGIKERTGFRLERRVA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHH
AVGRHMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQTQTTNLAVVAPGIAEALLA
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
TAIGLFAAIPAVVIYNIFARMIGSYKASLGDVAAQVLLLQSRDLDLSASGVKPVRSAQKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RVG
CCC
>Mature Secondary Structure 
GNNLMQADLSVWGMYHHADIVVKVVMIGLILASVVTWAIFFGKGAEILASKRRLKREQQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QLAEARSLDQASDIASAFEAKSLTTQLINEAQNELELSAGAEDNEGIKERTGFRLERRVA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHH
AVGRHMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIAQTQTTNLAVVAPGIAEALLA
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHH
TAIGLFAAIPAVVIYNIFARMIGSYKASLGDVAAQVLLLQSRDLDLSASGVKPVRSAQKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RVG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]