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The map label for this gene is yicJ [H]

Identifier: 238896517

GI number: 238896517

Start: 4496675

End: 4498126

Strand: Reverse

Name: yicJ [H]

Synonym: KP1_4701

Alternate gene names: 238896517

Gene position: 4498126-4496675 (Counterclockwise)

Preceding gene: 238896518

Following gene: 238896516

Centisome position: 85.7

GC content: 52.2

Gene sequence:

>1452_bases
GTGAATACCACTTCATCTGAGAGGGATTATATTGTGAATCACGATAATAAACTGTCATTTGCGGAGAAGCTGGGATATGG
CATGGGGGATGCAGCCTGCGGTATCGTTTACTCTTCGGTAACCATGTTTCTGACATGGTTTTATACGGATATTTACGGGC
TTTCTGCTGCCGCAGTCGGAGTGATGTTCCTGGTGACGCGGGTTCTGGATGCGATTACCGATCCGCTAACCGGCATTGTT
GCAGACCGTGTAAAGACCCGCTGGGGCCATTTTCGCCCGTGGCTTATCTGGTTTGCCGTACCTTATGCCGTGCTGGCGGT
AATGACCTTCACGACTCCGGAATTTGGCGCATCGGGTAAACTGGTTTATGCCTACCTGACCTACACCTTACTCATGCTGT
GTTACACCTTTATCAATATTCCCTACTGCGCATTGGGCGGAGTCATTACGCGTGATGAGAAGGATCGCCTTTCAGCCCAG
TCATATCGTTTTACGATCTCATCTCTGGCCGGTCTGATGGTTTCTGTCGCAACCCTGTTCCTGGTGGATTTTTTCGGTAA
AGAAAATAAGCAGTTTGGTTTTCAGGCGACAATGGGAATCATGGGCGCGATCGCTATTGTAATGCTGGCTTTTTGCTTCT
TCTCTACCAAAGAACGCGTGGCTCCAGCTGTTGAACAGCAGGGGAGCATACGCGAAGACCTCCGTCAGCTGCTGGCGAAT
GACCAGTGGCGTATTGTGGCGATAATTACTTTTTTCTCCAGTATGGCCGGGGTTATGCGCAGCGCCGCCACGCTCTATTA
TGCAACCTACCTGATGTTAGGCGGTGTGGAGTCAGCGGCGGGAACGGCCATGAAATCAGCATTTGTTTCCACCAGTGTCG
TTGGCACGATTATCGGCAGCATCGCCGCCGGATGGCTGGCCAAGCGCTATCGCGCGGTATCGCTGTTTAAAAATATCAAC
CTCCTGCTGGTCCTGGTTGGCGTCGTAATGTTCTTTGTGCCGCCGACCTGGCTGCCGGTGGTGTTCCCTTTATACTTCCT
GGTCGGCTTCTTCCATCAGATGTACCAGCCGTTTAAATGGAACATGATGGCCAACGCTGCCGATTATGGCGAATGGAAGT
TTGGCCGTCGCATCACGGGATTATCCTATTCCGGTAATCTGTTTGCTTTGAAAATGGGCATGGCGGTTGCTGGCGCCGCC
GTAGGTTTTTCGCTTGGGCTATTTGGCTATCAGGCGGGCGTAACGGCGCAGACTCCGTTGGCGACAATGGGAATTGTGGG
GCTGTTAACCCTCGGTCCATCACTATCTTACCTGCTCCTGTGGTGGCTGGCGCGTTTCTATAAGCTGGATGACAAAATGA
TGCAGACAATTCAGCGCGAGCTGTCCATGCGTCAGCAGCAGGGGCATTCAGAGACGCATTTGCCGCTAAACGCCGTTCCG
GAAAAGGCCTGA

Upstream 100 bases:

>100_bases
AAGACCAATCTTATAGATGTGTGACAACTTTCTCAGTTAACAGAAAACATAAACCCGATGCGAAAAATGACAATAGGATA
GTTTTTATCCTGCCTCTACA

Downstream 100 bases:

>100_bases
GGAGATGCGAAATATGACCCCTTCTGAATACCAGAATCCTATCTTATGCGCCGATTATTCCGACCCGGATATCGTGCGCG
TAGGCGATGATTTCTTTATG

Product: putative permease of the Na+:galactoside symporter family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNTTSSERDYIVNHDNKLSFAEKLGYGMGDAACGIVYSSVTMFLTWFYTDIYGLSAAAVGVMFLVTRVLDAITDPLTGIV
ADRVKTRWGHFRPWLIWFAVPYAVLAVMTFTTPEFGASGKLVYAYLTYTLLMLCYTFINIPYCALGGVITRDEKDRLSAQ
SYRFTISSLAGLMVSVATLFLVDFFGKENKQFGFQATMGIMGAIAIVMLAFCFFSTKERVAPAVEQQGSIREDLRQLLAN
DQWRIVAIITFFSSMAGVMRSAATLYYATYLMLGGVESAAGTAMKSAFVSTSVVGTIIGSIAAGWLAKRYRAVSLFKNIN
LLLVLVGVVMFFVPPTWLPVVFPLYFLVGFFHQMYQPFKWNMMANAADYGEWKFGRRITGLSYSGNLFALKMGMAVAGAA
VGFSLGLFGYQAGVTAQTPLATMGIVGLLTLGPSLSYLLLWWLARFYKLDDKMMQTIQRELSMRQQQGHSETHLPLNAVP
EKA

Sequences:

>Translated_483_residues
MNTTSSERDYIVNHDNKLSFAEKLGYGMGDAACGIVYSSVTMFLTWFYTDIYGLSAAAVGVMFLVTRVLDAITDPLTGIV
ADRVKTRWGHFRPWLIWFAVPYAVLAVMTFTTPEFGASGKLVYAYLTYTLLMLCYTFINIPYCALGGVITRDEKDRLSAQ
SYRFTISSLAGLMVSVATLFLVDFFGKENKQFGFQATMGIMGAIAIVMLAFCFFSTKERVAPAVEQQGSIREDLRQLLAN
DQWRIVAIITFFSSMAGVMRSAATLYYATYLMLGGVESAAGTAMKSAFVSTSVVGTIIGSIAAGWLAKRYRAVSLFKNIN
LLLVLVGVVMFFVPPTWLPVVFPLYFLVGFFHQMYQPFKWNMMANAADYGEWKFGRRITGLSYSGNLFALKMGMAVAGAA
VGFSLGLFGYQAGVTAQTPLATMGIVGLLTLGPSLSYLLLWWLARFYKLDDKMMQTIQRELSMRQQQGHSETHLPLNAVP
EKA
>Mature_483_residues
MNTTSSERDYIVNHDNKLSFAEKLGYGMGDAACGIVYSSVTMFLTWFYTDIYGLSAAAVGVMFLVTRVLDAITDPLTGIV
ADRVKTRWGHFRPWLIWFAVPYAVLAVMTFTTPEFGASGKLVYAYLTYTLLMLCYTFINIPYCALGGVITRDEKDRLSAQ
SYRFTISSLAGLMVSVATLFLVDFFGKENKQFGFQATMGIMGAIAIVMLAFCFFSTKERVAPAVEQQGSIREDLRQLLAN
DQWRIVAIITFFSSMAGVMRSAATLYYATYLMLGGVESAAGTAMKSAFVSTSVVGTIIGSIAAGWLAKRYRAVSLFKNIN
LLLVLVGVVMFFVPPTWLPVVFPLYFLVGFFHQMYQPFKWNMMANAADYGEWKFGRRITGLSYSGNLFALKMGMAVAGAA
VGFSLGLFGYQAGVTAQTPLATMGIVGLLTLGPSLSYLLLWWLARFYKLDDKMMQTIQRELSMRQQQGHSETHLPLNAVP
EKA

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=439, Percent_Identity=24.6013667425968, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI42713696, Length=160, Percent_Identity=30.625, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI211063479, Length=173, Percent_Identity=30.0578034682081, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082306, Length=455, Percent_Identity=43.2967032967033, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1786466, Length=469, Percent_Identity=38.592750533049, Blast_Score=344, Evalue=9e-96,
Organism=Escherichia coli, GI1787902, Length=476, Percent_Identity=32.1428571428571, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790561, Length=477, Percent_Identity=27.0440251572327, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI145693206, Length=459, Percent_Identity=26.797385620915, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI48994989, Length=459, Percent_Identity=26.1437908496732, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53460; Mature: 53460

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]