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The map label for this gene is hipO [H]

Identifier: 238893544

GI number: 238893544

Start: 1387322

End: 1388500

Strand: Direct

Name: hipO [H]

Synonym: KP1_1448

Alternate gene names: 238893544

Gene position: 1387322-1388500 (Clockwise)

Preceding gene: 238893543

Following gene: 238893545

Centisome position: 26.43

GC content: 59.46

Gene sequence:

>1179_bases
ATGAGTGATTATGTAATTCCAGAAATTAAAGCGACGGAAGCGGAAATGATTTCTATCCGTCATTATTTACATGCCAATCC
GGAATTAAGTCTTGAAGAGTTTAATACCAGCGAACTGGTCGCCAGCAAGCTGACGGAGTGGGGCTATCAGGTGACGCGCG
GTCTCGGCAAGACCGGCGTGGTCGGCAGCCTGAGCAAAGGCGATTCTCCGCGCACCATCGGTTTACGCGCCGATATGGAT
GCCCTGCCGATCGAGGAAACCACCGGTTTACCCTGGGCCAGCACGGCGCCAGGAAAAATGCACGCCTGCGGCCATGACGG
TCACACCACCATTCTGCTGGCGGCGGCGAAATATATCGCCTCGCCGGCCTGTCAGTTCAACGGCACGGTGCATCTGATTT
TTCAGCCGGCGGAAGAGGCTATCGGCGGCGCGGATTTAATGATTAAAGACGGCCTGTTCGAGCAGTTCCCCTGCGAACGC
ATCTTTGGCTTGCACAACATGCCAGGCCTGCCTGTAGGCAAGCTGGGCTTCTACGCCGGTAACTTCATGGCCTCGGCGGA
CACCGTCAAAATCACGATTACCGGCTACGGCGGCCACGGCGCCCACCCCGAGCGCACCGTCGACCCGATCGTCGCCGGTG
CGGCGCTGGTGATGGCCCTGCAGAGCATTGTGGCGCGCAACGTGCCGCCGGGGGAAACGGCAGTGGTCAGCGTCGGCACC
TTCCAGGCCGGTATCGCCTCCAACGTCATTCCGGAGAGCGCGGTGATGGAGCTGAGCGTGCGGGCGATGAAGCCGGAAAT
CCGCGACCTGCTGATCAAGCGTATTCACGAGCTCGCTGACTTTACCGCCAAAAGCTATGGCGCCAGCAGCGTAGTGGAGG
TTTACGACTCCTATCCGGTATTAACCAACAGTCCTGAAGAGACCGATTTCGCCCGGGCGCTGGCGCTGGAGGTGTTTGGC
CGCGAAGGGGTCCTGGAGTCGGTCTCGCCGATGAACGCCAGCGAGGATTTCGCTTTTATGCTGCGCGAACGCCCGGGCAG
CTACTTCCTGCTCGGCAATGGCGAGAAAGGGGAGAAGGGCGGTTGCATGGTGCACAACCCCGGCTACGACTTTAACGATG
ACATTATCACCACCGGCGCGACGCTGTTCGCCCGTCTGGTGGAAAAACACTGTCGCTAA

Upstream 100 bases:

>100_bases
TAAATAAGATGCGTCCATTCCAGGTATTAGAAATGCTGCTTGCATAAACTTTTCATCGCGATACCGTGATAAGTCCTTAA
TTTATTTCCCGGAGAGCGGC

Downstream 100 bases:

>100_bases
TCTCTGGAGAAGAACGCGAATGAAAAAATCACTGTTGCTATGGCTGGCATTAATGGCGTCGACGTCGGCGCTGGCCGAAG
GGGGAAAGGAGATCCGCTTC

Product: aminobenzoyl-glutamate utilization protein

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSDYVIPEIKATEAEMISIRHYLHANPELSLEEFNTSELVASKLTEWGYQVTRGLGKTGVVGSLSKGDSPRTIGLRADMD
ALPIEETTGLPWASTAPGKMHACGHDGHTTILLAAAKYIASPACQFNGTVHLIFQPAEEAIGGADLMIKDGLFEQFPCER
IFGLHNMPGLPVGKLGFYAGNFMASADTVKITITGYGGHGAHPERTVDPIVAGAALVMALQSIVARNVPPGETAVVSVGT
FQAGIASNVIPESAVMELSVRAMKPEIRDLLIKRIHELADFTAKSYGASSVVEVYDSYPVLTNSPEETDFARALALEVFG
REGVLESVSPMNASEDFAFMLRERPGSYFLLGNGEKGEKGGCMVHNPGYDFNDDIITTGATLFARLVEKHCR

Sequences:

>Translated_392_residues
MSDYVIPEIKATEAEMISIRHYLHANPELSLEEFNTSELVASKLTEWGYQVTRGLGKTGVVGSLSKGDSPRTIGLRADMD
ALPIEETTGLPWASTAPGKMHACGHDGHTTILLAAAKYIASPACQFNGTVHLIFQPAEEAIGGADLMIKDGLFEQFPCER
IFGLHNMPGLPVGKLGFYAGNFMASADTVKITITGYGGHGAHPERTVDPIVAGAALVMALQSIVARNVPPGETAVVSVGT
FQAGIASNVIPESAVMELSVRAMKPEIRDLLIKRIHELADFTAKSYGASSVVEVYDSYPVLTNSPEETDFARALALEVFG
REGVLESVSPMNASEDFAFMLRERPGSYFLLGNGEKGEKGGCMVHNPGYDFNDDIITTGATLFARLVEKHCR
>Mature_391_residues
SDYVIPEIKATEAEMISIRHYLHANPELSLEEFNTSELVASKLTEWGYQVTRGLGKTGVVGSLSKGDSPRTIGLRADMDA
LPIEETTGLPWASTAPGKMHACGHDGHTTILLAAAKYIASPACQFNGTVHLIFQPAEEAIGGADLMIKDGLFEQFPCERI
FGLHNMPGLPVGKLGFYAGNFMASADTVKITITGYGGHGAHPERTVDPIVAGAALVMALQSIVARNVPPGETAVVSVGTF
QAGIASNVIPESAVMELSVRAMKPEIRDLLIKRIHELADFTAKSYGASSVVEVYDSYPVLTNSPEETDFARALALEVFGR
EGVLESVSPMNASEDFAFMLRERPGSYFLLGNGEKGEKGGCMVHNPGYDFNDDIITTGATLFARLVEKHCR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42065; Mature: 41934

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYVIPEIKATEAEMISIRHYLHANPELSLEEFNTSELVASKLTEWGYQVTRGLGKTGV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
VGSLSKGDSPRTIGLRADMDALPIEETTGLPWASTAPGKMHACGHDGHTTILLAAAKYIA
EECCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHC
SPACQFNGTVHLIFQPAEEAIGGADLMIKDGLFEQFPCERIFGLHNMPGLPVGKLGFYAG
CCCEECCCEEEEEEECHHHHCCCCCEEEECCCHHHCCHHHHHCCCCCCCCCCHHHHHHHC
NFMASADTVKITITGYGGHGAHPERTVDPIVAGAALVMALQSIVARNVPPGETAVVSVGT
CEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
FQAGIASNVIPESAVMELSVRAMKPEIRDLLIKRIHELADFTAKSYGASSVVEVYDSYPV
HHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LTNSPEETDFARALALEVFGREGVLESVSPMNASEDFAFMLRERPGSYFLLGNGEKGEKG
CCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
GCMVHNPGYDFNDDIITTGATLFARLVEKHCR
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDYVIPEIKATEAEMISIRHYLHANPELSLEEFNTSELVASKLTEWGYQVTRGLGKTGV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
VGSLSKGDSPRTIGLRADMDALPIEETTGLPWASTAPGKMHACGHDGHTTILLAAAKYIA
EECCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHC
SPACQFNGTVHLIFQPAEEAIGGADLMIKDGLFEQFPCERIFGLHNMPGLPVGKLGFYAG
CCCEECCCEEEEEEECHHHHCCCCCEEEECCCHHHCCHHHHHCCCCCCCCCCHHHHHHHC
NFMASADTVKITITGYGGHGAHPERTVDPIVAGAALVMALQSIVARNVPPGETAVVSVGT
CEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
FQAGIASNVIPESAVMELSVRAMKPEIRDLLIKRIHELADFTAKSYGASSVVEVYDSYPV
HHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LTNSPEETDFARALALEVFGREGVLESVSPMNASEDFAFMLRERPGSYFLLGNGEKGEKG
CCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCC
GCMVHNPGYDFNDDIITTGATLFARLVEKHCR
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]