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The map label for this gene is gsk [H]

Identifier: 238893446

GI number: 238893446

Start: 1287961

End: 1289265

Strand: Direct

Name: gsk [H]

Synonym: KP1_1336

Alternate gene names: 238893446

Gene position: 1287961-1289265 (Clockwise)

Preceding gene: 238893445

Following gene: 238893449

Centisome position: 24.54

GC content: 59.0

Gene sequence:

>1305_bases
ATGAAATTTCCCGGTAAACGCAAATCTAAACACTATTTTCCCGTTAACGCCCGCGATCCGCTGCTGCAGCAAATTCAGCC
GGAGAATGAATCCAGCGTCTCCTGGGTGGTCGGTATCGACCAGACGCTGGTGGATATCGAAGCGAAAGTGGATGAGGCGT
TTATCGTGCGCTACGGCCTGAGCGCGGGCCATTCGCTGGTGATTGAAGATGACGTCGCCGAGGCGCTGTACCAGGAGCTG
GTGCGCAACAATCTCATTACCCATCAGTTTGCCGGCGGCACCATCGGCAATACCATGCACAACTACTCGGTGCTGGCGGA
CGATCGCTCGGTGCTGCTTGGCGTGATGTGCAGCAATATCGAAATCGGCGGCTATGCCTATCGTTACCTGTGCAATACCT
CCAGCCGCACCGATCTGAACTATCTGCAGGGCGTCGACGGCGCCATTGGCCGCTGCTTTACCCTGATCGGTGACAGCGGC
GAGCGCACCTTCGCCATCAGCCCGGGCCACATGAACAAGCTGCGTCCGGAAAGCATTCCGGAAGCGGTGATCGCCGGCGC
CTCGGCGCTGGTGCTGACCTCTTACCTGGTCCGCTGCAAGCCGGGCGAGCCGATGCCGGACGCCACGATGAAGGCTATTG
AGTATGCCAAAAAGCACGATGTGCCGGTGGTGTTAACCCTCGGAACCAAATACGTGATTGCCGATAACCCGGCGTGGTGG
CAGGAGTTCCTGCAGGAGCATGTCTCTATTCTGGCAATGAACGAAGAGGAAGGGGAAGCGCTGACCGGCTTTGCCGATCC
GCTGTCAGCGGCGAATAAGGCGCTGGACTGGGTCGACCTGGTGCTGTGCACCGCCGGCCCGGCGGGCCTGTATATGGCAG
GCTTCACTGAAGAAGAGGCGAAGCGTAAAACCCAGCATCCGCTGCTGCCGGGGGCGATCCCGGAGTTTAACCAGTTTGAA
TTCAGCCGCGCGATGCGTCACCAGGATTGCGTTAATCCGCTGCGCATATATTCCCATATCGCTCCCTATATGGGCGGCCC
CGAGAAGATCATGAACACCAACGGCGCAGGCGACGGCGCGCTGGCGGCGCTGCTGCATGACATCACCGCCAATAACTACC
ACCGCAATAACGTACCCAACTCCAGCAAGCACAAATGCAAATGGCTGACCTACTCCTCGCTGGCGCAGGTGTGTAAATAT
GCCAACCGCGTGAGCTATCAGGTGCTGAACCAGCACTCGCCGCGTTTAACCCGCGGCCTGCCGGAGCGTGAGGACAGCCT
GGAAGAGGCGTACTGGGATCGGTAA

Upstream 100 bases:

>100_bases
TGAGATGATGGTCAATCTGACGGCGCCTTATCGCTGATCGCGCGCAGGGCGGGGAATATGCTACTATTTCCCGCTTGTTC
CCTGTTATTTAAGCGCCACT

Downstream 100 bases:

>100_bases
GCGCGTCCCTCTCCCGGCGGGGAGAGGGCAGTACATCAGCCGGTGACCACTTCGCCGGCCGGTGGCGTTTCCAGAAGCCG
CAGCATGGCGCGGGCAATTT

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPENESSVSWVVGIDQTLVDIEAKVDEAFIVRYGLSAGHSLVIEDDVAEALYQEL
VRNNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGGYAYRYLCNTSSRTDLNYLQGVDGAIGRCFTLIGDSG
ERTFAISPGHMNKLRPESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHDVPVVLTLGTKYVIADNPAWW
QEFLQEHVSILAMNEEEGEALTGFADPLSAANKALDWVDLVLCTAGPAGLYMAGFTEEEAKRKTQHPLLPGAIPEFNQFE
FSRAMRHQDCVNPLRIYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANNYHRNNVPNSSKHKCKWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEEAYWDR

Sequences:

>Translated_434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPENESSVSWVVGIDQTLVDIEAKVDEAFIVRYGLSAGHSLVIEDDVAEALYQEL
VRNNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGGYAYRYLCNTSSRTDLNYLQGVDGAIGRCFTLIGDSG
ERTFAISPGHMNKLRPESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHDVPVVLTLGTKYVIADNPAWW
QEFLQEHVSILAMNEEEGEALTGFADPLSAANKALDWVDLVLCTAGPAGLYMAGFTEEEAKRKTQHPLLPGAIPEFNQFE
FSRAMRHQDCVNPLRIYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANNYHRNNVPNSSKHKCKWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEEAYWDR
>Mature_434_residues
MKFPGKRKSKHYFPVNARDPLLQQIQPENESSVSWVVGIDQTLVDIEAKVDEAFIVRYGLSAGHSLVIEDDVAEALYQEL
VRNNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGGYAYRYLCNTSSRTDLNYLQGVDGAIGRCFTLIGDSG
ERTFAISPGHMNKLRPESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHDVPVVLTLGTKYVIADNPAWW
QEFLQEHVSILAMNEEEGEALTGFADPLSAANKALDWVDLVLCTAGPAGLYMAGFTEEEAKRKTQHPLLPGAIPEFNQFE
FSRAMRHQDCVNPLRIYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANNYHRNNVPNSSKHKCKWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEEAYWDR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=89.8617511520737, Blast_Score=828, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48136; Mature: 48136

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQIQPENESSVSWVVGIDQTLVDIEAKVDEAFIVRYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECC
SAGHSLVIEDDVAEALYQELVRNNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGGYAYRYLCNTSSRTDLNYLQGVDGAIGRCFTLIGDSGERTFAISPGHMNKLRPESIP
EECCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCHHCC
EAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHDVPVVLTLGTKYVIADNPAWW
HHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHH
QEFLQEHVSILAMNEEEGEALTGFADPLSAANKALDWVDLVLCTAGPAGLYMAGFTEEEA
HHHHHHHHHEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
KRKTQHPLLPGAIPEFNQFEFSRAMRHQDCVNPLRIYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANNYHRNNVPNSSKHKCKWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSLEEAYWDR
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGKRKSKHYFPVNARDPLLQQIQPENESSVSWVVGIDQTLVDIEAKVDEAFIVRYGL
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECC
SAGHSLVIEDDVAEALYQELVRNNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNI
CCCCEEEEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCEEEECCHHHHHHHHHCCE
EIGGYAYRYLCNTSSRTDLNYLQGVDGAIGRCFTLIGDSGERTFAISPGHMNKLRPESIP
EECCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCHHCC
EAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKKHDVPVVLTLGTKYVIADNPAWW
HHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHH
QEFLQEHVSILAMNEEEGEALTGFADPLSAANKALDWVDLVLCTAGPAGLYMAGFTEEEA
HHHHHHHHHEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
KRKTQHPLLPGAIPEFNQFEFSRAMRHQDCVNPLRIYSHIAPYMGGPEKIMNTNGAGDGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCHHH
LAALLHDITANNYHRNNVPNSSKHKCKWLTYSSLAQVCKYANRVSYQVLNQHSPRLTRGL
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PEREDSLEEAYWDR
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]