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The map label for this gene is mocR [H]

Identifier: 238893426

GI number: 238893426

Start: 1265542

End: 1267041

Strand: Direct

Name: mocR [H]

Synonym: KP1_1313

Alternate gene names: 238893426

Gene position: 1265542-1267041 (Clockwise)

Preceding gene: 238893424

Following gene: 238893433

Centisome position: 24.11

GC content: 63.53

Gene sequence:

>1500_bases
GTGCCATTAGAGTATGTTTTTATGGGGCCACGAGGAGGCAATATGAATATACCGGACGAGGGGTTTTTTACGCTGTTGAC
GCAGGGGATGCGGAACCGCACGGTCGAAACCTTACAGCGCGCCCTTTACCACACCTTACGTGACGCTATCCTGCAGGGAA
CCCTGACGGCCCGCTGCCGTTTACCCGGATCGCGGGTGATGGCCGAACGGCTACACCTGTCGCGGAATACGGTCAATGCC
GCACTGGAACAGCTGGCGCTGGAGGGGTACCTGATACGGAGCCGTCAGGGAACGCAGGTGGCACCACTCGCCTCCTGCCG
CCAGGAGGCGGGTCAGATGCCGCCCGTCGTGCTGCCTGAGCGGCTGCAAAGGCTGCCAGCCGCGATGCGCCGCGACTCAC
CGACGCTGGCATTTACGCCAGGCATGCCGGCGGTAAACTATTTCCCGCTGCCGCTGCCGCTGTGGCGGCGACTGATGGAT
AACGTGCTACGCGAAGATGGTAGCGCGCTGCTGGGTTATGGCGAAGCCGCGGGCGATCCTATGCTGCGAGAGGCTATCGC
TCGTCATCTGGCGCTCTCCCGGGGCATCCGGTGCGATATCCGGCAGATCGTCATCACCGAAGGCGCGCTGGAAGGCGTCA
ACTTATGCGCCTCGCTACTGACCAACCCGGGCGACAGCGTGTGGCTGGAAGAACCGGGGTACCTGGGGGCGAGGAGTGGC
TTTCAGCGGGCGGGACTGCGGGTCAGAGGAATGGCTGTCGACGATGAAGGGATGTGTATTGCCAACGGCGTCGCGGAGCC
GCCCCGGCTCATTTTCACCTCTCCTTCACACCAGTATCCCTGTGGGAGCATCATGAGCGCCGGGCGCCGTCTGGCGCTCG
TGGAATATGCCCGCCGGCACGGGGCGTGGATTGTGGAGGATGACTACGACAGCGAGTTTCGCCATAGCGGAGAACCGATC
CCGGCGATGCTGGGAATGGTGCCTGATGCCCCGGTGGTCTATCTCGGCACCTTCAGCAAAACGCTGTTTCCGGCGTTGCG
TATCGGTTTTATGGTTATGCCGCCCGCGCTGGCGGATGCTGCTCAGGACGCCATTGGCGCGCTGCTGCGCGGGGGACACC
GTGCTGAACAGCGGGCGCTGGCCAGATTTATCGAGAAGGGACACTATGCGCGCCATCTGGCAGCGATGCGCCGCCTGTAC
CGTAAACGTCAGCAACAGCTGCGCGAGGCGCTGGCGCAAGAGATAACCGTGCCGTGCGACGTTCTCGGCGGGGGAGGGGG
GATGCACCTGACGGTGGCGATGGAGGGCGTTAATGACCGGACGCTTGCGCAGCAGGCGCGCCAGTTTCAGCTGGCGCCCG
CCGCGTTAAGTCATTTCTATCTCGACCCGCAGCGAGCGCGGAGCGGACTGGTGCTTGGGTATGGCAATACCTCTGCTTCT
CGCTATCTCCCGGCGCTGCGGACCCTAAATCGCCTTATTGCGCAGCACCGGCGCGCGTGA

Upstream 100 bases:

>100_bases
CGCGACGCCGAGCGCCTGGCCAAACTGATTATATTCGCACATTGCGGTTTCCTTATTGGGGATTTACAGGCAGCGTACGC
GCTCGCTGGTTCCATAAAAA

Downstream 100 bases:

>100_bases
GGGTAAAGACATCGTAGAAGGATAGCTCGCCTTTGGTGGCGACCATCTTTTTGAGCTGCGCCTTCTGCTCGCTATCGACG
TCTGGCGACTGCAGGATACG

Product: putative GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MPLEYVFMGPRGGNMNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNA
ALEQLALEGYLIRSRQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLPLWRRLMD
NVLREDGSALLGYGEAAGDPMLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGARSG
FQRAGLRVRGMAVDDEGMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPI
PAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALARFIEKGHYARHLAAMRRLY
RKRQQQLREALAQEITVPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSAS
RYLPALRTLNRLIAQHRRA

Sequences:

>Translated_499_residues
MPLEYVFMGPRGGNMNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNA
ALEQLALEGYLIRSRQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLPLWRRLMD
NVLREDGSALLGYGEAAGDPMLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGARSG
FQRAGLRVRGMAVDDEGMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPI
PAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALARFIEKGHYARHLAAMRRLY
RKRQQQLREALAQEITVPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSAS
RYLPALRTLNRLIAQHRRA
>Mature_498_residues
PLEYVFMGPRGGNMNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNAA
LEQLALEGYLIRSRQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLPLWRRLMDN
VLREDGSALLGYGEAAGDPMLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGARSGF
QRAGLRVRGMAVDDEGMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPIP
AMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALARFIEKGHYARHLAAMRRLYR
KRQQQLREALAQEITVPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASR
YLPALRTLNRLIAQHRRA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=315, Percent_Identity=22.5396825396825, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33469970, Length=315, Percent_Identity=22.5396825396825, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790797, Length=434, Percent_Identity=29.0322580645161, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787710, Length=410, Percent_Identity=27.8048780487805, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54986; Mature: 54854

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50949 HTH_GNTR ; PS00527 RIBOSOMAL_S14

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEYVFMGPRGGNMNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCR
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
LPGSRVMAERLHLSRNTVNAALEQLALEGYLIRSRQGTQVAPLASCRQEAGQMPPVVLPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHCCCCCCHHHH
RLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLPLWRRLMDNVLREDGSALLGYGEAAGDP
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCH
MLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGARSG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
FQRAGLRVRGMAVDDEGMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRH
HHHCCCEEEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHC
GAWIVEDDYDSEFRHSGEPIPAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADA
CCEEEECCCCCHHHHCCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHH
AQDAIGALLRGGHRAEQRALARFIEKGHYARHLAAMRRLYRKRQQQLREALAQEITVPCD
HHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSAS
EECCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCEEEEECCCCHH
RYLPALRTLNRLIAQHRRA
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLEYVFMGPRGGNMNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCR
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
LPGSRVMAERLHLSRNTVNAALEQLALEGYLIRSRQGTQVAPLASCRQEAGQMPPVVLPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHCCCCCCHHHH
RLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLPLWRRLMDNVLREDGSALLGYGEAAGDP
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCH
MLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGARSG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
FQRAGLRVRGMAVDDEGMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRH
HHHCCCEEEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHC
GAWIVEDDYDSEFRHSGEPIPAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADA
CCEEEECCCCCHHHHCCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHH
AQDAIGALLRGGHRAEQRALARFIEKGHYARHLAAMRRLYRKRQQQLREALAQEITVPCD
HHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSAS
EECCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCEEEEECCCCHH
RYLPALRTLNRLIAQHRRA
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]