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The map label for this gene is coaE [H]

Identifier: 238893082

GI number: 238893082

Start: 909669

End: 910289

Strand: Reverse

Name: coaE [H]

Synonym: KP1_0926

Alternate gene names: 238893082

Gene position: 910289-909669 (Counterclockwise)

Preceding gene: 238893085

Following gene: 238893081

Centisome position: 17.34

GC content: 60.06

Gene sequence:

>621_bases
ATGGGGTACACAGTCGCGTTAACAGGCGGGATCGGCAGCGGTAAAAGTACGGTCGCCGACGCCTTCGCGCAGCTTGGGGT
TAAGGTTATCGATGCCGATGTTATCGCCCGTCAGGTGGTCGAGCCCGGTACCCCGGCGCTCCAGGCCATTGTCGGCCACT
TTGGACCACAAATGATTGCCCCCGACGGCACGCTGAACCGCCGCCTGCTGCGGGAAAAAATTTTTGCTCACGTGGAGGAA
AAAGCCTGGCTCAATGCGCTGTTGCACCCGCTGATTCAGCAGGAAACGCGCCGCCAGATGCAGGCCGCCACCTCCCCTTA
TCTCCTCTGGGTCGTACCTTTGCTGGTCGAAAACCGCCTGTCCGGCCAGGCCGATCGCGTACTGGTCGTCGATGTGCCGA
AAGAGACGCAAATCGAACGCACCATGCTGCGCGATAAGGTCAGCCGCGAACATGCTGAACATATTCTTGCCGCCCAGGCC
ACGCGCCAGCAGCGCCTGGCCGTCGCGGACGATGTTATTGAAAACACTGGCACGCCGGATGCAGTGGCATCGGATGTTGC
CCGCCTGCACGAAAAGTATTTAACGCTGGCATCGCAGGCCGCCTCACAGGAAAACTCGTAA

Upstream 100 bases:

>100_bases
GGGCCCTCACGACATGCTCACTGTCGCCTCCCCGGCGCGCTGCCAGTCATCGCTGTCTGCCTGCAAAAAATACGAGCAAT
CCGTTTCAGGGTCAGAAGAT

Downstream 100 bases:

>100_bases
TGCATACCCCCGTTCTGTTTGAACATCCTCTTAATGAGAAAATGCGCACCTGGCTGCGCATCGAATTTCTGATCCAGCAG
ATGGCTTTCCGTCCGCAGAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MGYTVALTGGIGSGKSTVADAFAQLGVKVIDADVIARQVVEPGTPALQAIVGHFGPQMIAPDGTLNRRLLREKIFAHVEE
KAWLNALLHPLIQQETRRQMQAATSPYLLWVVPLLVENRLSGQADRVLVVDVPKETQIERTMLRDKVSREHAEHILAAQA
TRQQRLAVADDVIENTGTPDAVASDVARLHEKYLTLASQAASQENS

Sequences:

>Translated_206_residues
MGYTVALTGGIGSGKSTVADAFAQLGVKVIDADVIARQVVEPGTPALQAIVGHFGPQMIAPDGTLNRRLLREKIFAHVEE
KAWLNALLHPLIQQETRRQMQAATSPYLLWVVPLLVENRLSGQADRVLVVDVPKETQIERTMLRDKVSREHAEHILAAQA
TRQQRLAVADDVIENTGTPDAVASDVARLHEKYLTLASQAASQENS
>Mature_205_residues
GYTVALTGGIGSGKSTVADAFAQLGVKVIDADVIARQVVEPGTPALQAIVGHFGPQMIAPDGTLNRRLLREKIFAHVEEK
AWLNALLHPLIQQETRRQMQAATSPYLLWVVPLLVENRLSGQADRVLVVDVPKETQIERTMLRDKVSREHAEHILAAQAT
RQQRLAVADDVIENTGTPDAVASDVARLHEKYLTLASQAASQENS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=37.7551020408163, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=37.7551020408163, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI110227607, Length=180, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI110227605, Length=165, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI110227603, Length=165, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI110227601, Length=165, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI205277394, Length=165, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786292, Length=204, Percent_Identity=75.4901960784314, Blast_Score=295, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17554944, Length=187, Percent_Identity=34.7593582887701, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320402, Length=182, Percent_Identity=36.8131868131868, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=32.2916666666667, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24658602, Length=170, Percent_Identity=30.5882352941176, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22469; Mature: 22338

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYTVALTGGIGSGKSTVADAFAQLGVKVIDADVIARQVVEPGTPALQAIVGHFGPQMIA
CCEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
PDGTLNRRLLREKIFAHVEEKAWLNALLHPLIQQETRRQMQAATSPYLLWVVPLLVENRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SGQADRVLVVDVPKETQIERTMLRDKVSREHAEHILAAQATRQQRLAVADDVIENTGTPD
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVASDVARLHEKYLTLASQAASQENS
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GYTVALTGGIGSGKSTVADAFAQLGVKVIDADVIARQVVEPGTPALQAIVGHFGPQMIA
CEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
PDGTLNRRLLREKIFAHVEEKAWLNALLHPLIQQETRRQMQAATSPYLLWVVPLLVENRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SGQADRVLVVDVPKETQIERTMLRDKVSREHAEHILAAQATRQQRLAVADDVIENTGTPD
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVASDVARLHEKYLTLASQAASQENS
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA