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The map label for this gene is yjjG [H]

Identifier: 238892961

GI number: 238892961

Start: 767648

End: 768325

Strand: Direct

Name: yjjG [H]

Synonym: KP1_0788

Alternate gene names: 238892961

Gene position: 767648-768325 (Clockwise)

Preceding gene: 238892960

Following gene: 238892962

Centisome position: 14.63

GC content: 57.96

Gene sequence:

>678_bases
ATGAAATGGGACTGGATTTTCTTTGATGCCGATGAAACGCTGTTTACGTTTGATTCTTTCAGCGGCTTGCAGCGGATGTT
TCTCGACTACAGCGTGACCTTTACCGCCGAAGATTTTCAGGACTATCAGGCCGTGAACAAGCCGCTATGGGTGGATTACC
AAAACGGCGCCATCACCTCGCTGCAGCTGCAGCACCAGCGTTTTGACAGCTGGGCGGAACGTTTGAATGTGCCGCCCGGG
GAACTCAACGACGCGTTTATGAATGCGATGGCGGAAATCTGTGCCCCGTTGCCGGGCGCGGTCTCGCTGCTCAACGCGCT
GCAGGGCAAGGTCAGAATGGGCATCATCACCAACGGCTTTACCTCGCTGCAGCAGACTCGTCTGGAGCGCACAGGTTTAC
GCGATCACTTTGATTTGCTGATTATTTCTGAACAGGTGGGTGTCGCCAAGCCGGACGCGCGTATTTTCGATTATGCGCTG
GCGCAGGCGGGTAACCCACCGCGCTCGCGGGTGCTGATGGTCGGTGATACCGCCGAGTCGGATATTCGCGGCGGCGTGAA
CGCCGGACTGGCGACCTGCTGGCTCAATGCGCATCAGCGCGAGCTGCCGGCGGACCTCGAGCCGGACTGGACGGTGACCT
CGTTAAGCGAACTGGAGCAGCTCCTGTGTAAACACTGA

Upstream 100 bases:

>100_bases
ATGAGGCAACCATCCGCCGCAACTACTATCCTACGGCCGACGGACGCGAAGACGCCATTATTATGGCTCTGCCAATCAGT
ATGTAACACAAGGTGATACG

Downstream 100 bases:

>100_bases
TTGCCTCCCCCCCGTTGATGGGTAAAATAGCCGCAATTTTTCGTATTCCACATGCGTGGCCCATGGCCGCGTTTACTTAG
AAGATTAATTATGACGTTGT

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKWDWIFFDADETLFTFDSFSGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHQRFDSWAERLNVPPG
ELNDAFMNAMAEICAPLPGAVSLLNALQGKVRMGIITNGFTSLQQTRLERTGLRDHFDLLIISEQVGVAKPDARIFDYAL
AQAGNPPRSRVLMVGDTAESDIRGGVNAGLATCWLNAHQRELPADLEPDWTVTSLSELEQLLCKH

Sequences:

>Translated_225_residues
MKWDWIFFDADETLFTFDSFSGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHQRFDSWAERLNVPPG
ELNDAFMNAMAEICAPLPGAVSLLNALQGKVRMGIITNGFTSLQQTRLERTGLRDHFDLLIISEQVGVAKPDARIFDYAL
AQAGNPPRSRVLMVGDTAESDIRGGVNAGLATCWLNAHQRELPADLEPDWTVTSLSELEQLLCKH
>Mature_225_residues
MKWDWIFFDADETLFTFDSFSGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHQRFDSWAERLNVPPG
ELNDAFMNAMAEICAPLPGAVSLLNALQGKVRMGIITNGFTSLQQTRLERTGLRDHFDLLIISEQVGVAKPDARIFDYAL
AQAGNPPRSRVLMVGDTAESDIRGGVNAGLATCWLNAHQRELPADLEPDWTVTSLSELEQLLCKH

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=241, Percent_Identity=30.2904564315353, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1790833, Length=225, Percent_Identity=84, Blast_Score=406, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25303; Mature: 25303

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWDWIFFDADETLFTFDSFSGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITS
CCCEEEEEECCCCEEEEHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCEEEEECCCCEEE
LQLQHQRFDSWAERLNVPPGELNDAFMNAMAEICAPLPGAVSLLNALQGKVRMGIITNGF
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCH
TSLQQTRLERTGLRDHFDLLIISEQVGVAKPDARIFDYALAQAGNPPRSRVLMVGDTAES
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHEEEEEECCCCH
DIRGGVNAGLATCWLNAHQRELPADLEPDWTVTSLSELEQLLCKH
HHCCCCCCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKWDWIFFDADETLFTFDSFSGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITS
CCCEEEEEECCCCEEEEHHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCEEEEECCCCEEE
LQLQHQRFDSWAERLNVPPGELNDAFMNAMAEICAPLPGAVSLLNALQGKVRMGIITNGF
EHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCH
TSLQQTRLERTGLRDHFDLLIISEQVGVAKPDARIFDYALAQAGNPPRSRVLMVGDTAES
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHEEEEEECCCCH
DIRGGVNAGLATCWLNAHQRELPADLEPDWTVTSLSELEQLLCKH
HHCCCCCCCHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]