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The map label for this gene is rhtC [H]

Identifier: 238892900

GI number: 238892900

Start: 709978

End: 710640

Strand: Reverse

Name: rhtC [H]

Synonym: KP1_0721

Alternate gene names: 238892900

Gene position: 710640-709978 (Counterclockwise)

Preceding gene: 238892901

Following gene: 238892899

Centisome position: 13.54

GC content: 62.29

Gene sequence:

>663_bases
ATGCATACCTTATCGACGCTCTTTCCCGCCGTCTTCCCGGCGCTAGCCCTGTCCCACTTTGTCGCTCTGCTCAGTCCGGG
CCCTGATTTTTTTCTGCTGATCGGCTACGCCGTGCGCTACCGGATCCGCGGCAGCATCGGATTGTGTCTCGGCATCGCCG
CAGGCAATGCGCTGTATATTGTGCTCGCCATCGTCGGCTGGGGGCTTCTGCGCCAGGCGCCGCTGCTTTTTTTGCTCATC
GAACTGCTGGGGGCGGGCTATTTATTGTGGATTGGCAGCCTGCTGATACGCAGCCGTCCCGCGACGCTGGCGGTGGAGAG
CGTTCGCGCAGCGCGTCCGGGGTTCGGCAGGCAACTGCTGCTGGGGCTGGGGTCATCGCTGCTCAACCCCAAAAACGCCC
TGTTTTATCTGGCGCTGATGACTTCCCTGCTCGGGCCGGCTGTGACCCTGCTTCAGCAAACGGTGAGCGGGCTGTGGATG
GTCAGCGTGGTGTTCTTCTGGGATTTACTGCTGGTGAGCGCGATTGCGCTGCCGCAGATACAGCGCCGCCTGGGCGCCAT
CGTCTGGCGGCTCGAGCGGGCGGCGGGGGCGATCCTGATGCTCTTCGGCCTGTGGATTATCTGGCGATTTTTGCACGACC
TCGCCGTCAGGCTATATGCTTAA

Upstream 100 bases:

>100_bases
CCGCCACGCCGCGGCAGTATGCGCAAAGCAGATCAATATCTGACAATAAGTAATACGCCACCTGGCGTAGGGTGGCCTCT
GCACCATTATCGAGGCCACT

Downstream 100 bases:

>100_bases
GCATATGGAAAAACTCGCTGAACTGAAACGCGCCAAACTGCTGGCGCTGTCGCTGCTGCTGATTGCAGCCGCCATTTTTA
TCACTACCCTCGCGCTACCA

Product: amino acid threonine exporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MHTLSTLFPAVFPALALSHFVALLSPGPDFFLLIGYAVRYRIRGSIGLCLGIAAGNALYIVLAIVGWGLLRQAPLLFLLI
ELLGAGYLLWIGSLLIRSRPATLAVESVRAARPGFGRQLLLGLGSSLLNPKNALFYLALMTSLLGPAVTLLQQTVSGLWM
VSVVFFWDLLLVSAIALPQIQRRLGAIVWRLERAAGAILMLFGLWIIWRFLHDLAVRLYA

Sequences:

>Translated_220_residues
MHTLSTLFPAVFPALALSHFVALLSPGPDFFLLIGYAVRYRIRGSIGLCLGIAAGNALYIVLAIVGWGLLRQAPLLFLLI
ELLGAGYLLWIGSLLIRSRPATLAVESVRAARPGFGRQLLLGLGSSLLNPKNALFYLALMTSLLGPAVTLLQQTVSGLWM
VSVVFFWDLLLVSAIALPQIQRRLGAIVWRLERAAGAILMLFGLWIIWRFLHDLAVRLYA
>Mature_220_residues
MHTLSTLFPAVFPALALSHFVALLSPGPDFFLLIGYAVRYRIRGSIGLCLGIAAGNALYIVLAIVGWGLLRQAPLLFLLI
ELLGAGYLLWIGSLLIRSRPATLAVESVRAARPGFGRQLLLGLGSSLLNPKNALFYLALMTSLLGPAVTLLQQTVSGLWM
VSVVFFWDLLLVSAIALPQIQRRLGAIVWRLERAAGAILMLFGLWIIWRFLHDLAVRLYA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786522, Length=193, Percent_Identity=26.4248704663212, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24076; Mature: 24076

Theoretical pI: Translated: 11.51; Mature: 11.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLSTLFPAVFPALALSHFVALLSPGPDFFLLIGYAVRYRIRGSIGLCLGIAAGNALYI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
VLAIVGWGLLRQAPLLFLLIELLGAGYLLWIGSLLIRSRPATLAVESVRAARPGFGRQLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
LGLGSSLLNPKNALFYLALMTSLLGPAVTLLQQTVSGLWMVSVVFFWDLLLVSAIALPQI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLGAIVWRLERAAGAILMLFGLWIIWRFLHDLAVRLYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHTLSTLFPAVFPALALSHFVALLSPGPDFFLLIGYAVRYRIRGSIGLCLGIAAGNALYI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
VLAIVGWGLLRQAPLLFLLIELLGAGYLLWIGSLLIRSRPATLAVESVRAARPGFGRQLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
LGLGSSLLNPKNALFYLALMTSLLGPAVTLLQQTVSGLWMVSVVFFWDLLLVSAIALPQI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLGAIVWRLERAAGAILMLFGLWIIWRFLHDLAVRLYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]