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The map label for this gene is cusC [H]

Identifier: 238892870

GI number: 238892870

Start: 674563

End: 675948

Strand: Reverse

Name: cusC [H]

Synonym: KP1_0689

Alternate gene names: 238892870

Gene position: 675948-674563 (Counterclockwise)

Preceding gene: 238892875

Following gene: 238892869

Centisome position: 12.88

GC content: 60.17

Gene sequence:

>1386_bases
ATGCGCTCAATACAGCTACTTACCCTCAGCGTGATATTTGCCTTAACCGGCTGTCTCTCGCTCGCTCCGGACTACCAGCG
CCCTGTCGCGCCGGTGCCGCAGCAGTTCTCTCTCAGCCAGAACAAGCTGGTTACTGCGAAAGTGGGCTATCAAGAGACCG
GCTGGCGCACCTTTTTCGTCGACCCGCAGGTGAAAAGCCTGATTAGCACCGCGCTGACCAACAACCGCGATCTACGGATG
GCGACGCTGAAAGTGCAGGAAGCCCGCGCCCAGTACCGGGTAACCGACGCCGACCGCTACCCGCAGCTTAACGGTGACGG
CAGCACCACCTATGGCGGCAAGCTCAAAGGCGACACCACCACCAGCAGCGATTATGCCGCCGGCTTAAACCTCAGCTACG
ACCTCGACTTCTTTGGCCGGTTGAAAAACCTTAGCGAAGCCGACCGACAGAACTTCTTCGCCAGCGAAGAGGCGCGGCGC
GCGGTGCATATCCTGTTGATTGCTAACGTTTCACAAAGCTACTTCAACCAGCGGCTGGCGGCAGCGCAGCTGCAGGTGGC
CAACGACACCTTGCAGAACTATCAGCAGTCTTACGCCTTCGTTGAAAAACAGCTGCTGACCGGGAGCACCACCGTGCTGG
CGCTGGAACAGGCGCGCGGCATGATCGAGAGCACCCGCGCCGATATCGCCAAACGTCAGGGCCAGCTGGCGCAGGCCAAT
AACGCCCTGCAGCTACTGCTCGGCAGCTATCAACATCTGCCGGACGATAGCGCCAGCAGCGCGGTAGACCTGCAAGGCGT
AACCCTGCCGCCATCGCTCTCCTCAGCGATCCTGCTGCAGCGGCCGGATATTCTGGAAGCCGAACACAGCCTGCAAGCGG
CCAACGCCAACATCGGCGCCGCGCGGGCGGCCTTCTTCCCGTCGATCACCCTGACCAGCTCGCTCTCCGGCAGCAGCAGC
GAGCTCTTCAGCCTGTTTAACGCCGGCGGCGCGATGTGGAACTTTATCCCCAAAATTGAACTGCCAATTTTCAACGCCGG
GCGTAATCAGGCCAACCTCGATCTGGCGGAAATCCGCCAGCAGCAGCAGGTGGTCAACTATGAACAAAAAATACAGTCCG
CCTTTAAAGAGGTGGCCGACGCGCTGGCCCAGCGCCAAAGCCTGGCCGATCAGATTGCCGCCCAGCAGCGCTATCTCGCT
TCACTAAATATCACCCTGCAGCGCGCCACTGCGCTCTATCGCCACGGCGCGGTCAGCTACATCGAAGTCCTGAGCGCCCA
GCGCGACATTTTCACCACCCGACAAACCCTGCTGGAACTCAACTATTCCCGTCAGGCGAATGAAATCACCCTGTTCACCG
CTCTCGGCGGCGGCTGGATGGAATAA

Upstream 100 bases:

>100_bases
ATCAGGAAAATGACAGCTTTGTCATTTTCCCGTCACGCCCTGAACAGAGCCCGCTACGTAAAGTAGCCGCCATGGATAAA
TCGTCGAAACTTCTGCCACC

Downstream 100 bases:

>100_bases
CCCGAGGAGTCTTGATTATGAATTCACTGTCTAAAATCGCCCTGTTTACCCTGCTCTCTGGCGCAGTGTTCGCCGCCCAG
GCTGCCGAACCGCACGCCGG

Product: copper/silver efflux system outer membrane protein CusC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRSIQLLTLSVIFALTGCLSLAPDYQRPVAPVPQQFSLSQNKLVTAKVGYQETGWRTFFVDPQVKSLISTALTNNRDLRM
ATLKVQEARAQYRVTDADRYPQLNGDGSTTYGGKLKGDTTTSSDYAAGLNLSYDLDFFGRLKNLSEADRQNFFASEEARR
AVHILLIANVSQSYFNQRLAAAQLQVANDTLQNYQQSYAFVEKQLLTGSTTVLALEQARGMIESTRADIAKRQGQLAQAN
NALQLLLGSYQHLPDDSASSAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGAARAAFFPSITLTSSLSGSSS
ELFSLFNAGGAMWNFIPKIELPIFNAGRNQANLDLAEIRQQQQVVNYEQKIQSAFKEVADALAQRQSLADQIAAQQRYLA
SLNITLQRATALYRHGAVSYIEVLSAQRDIFTTRQTLLELNYSRQANEITLFTALGGGWME

Sequences:

>Translated_461_residues
MRSIQLLTLSVIFALTGCLSLAPDYQRPVAPVPQQFSLSQNKLVTAKVGYQETGWRTFFVDPQVKSLISTALTNNRDLRM
ATLKVQEARAQYRVTDADRYPQLNGDGSTTYGGKLKGDTTTSSDYAAGLNLSYDLDFFGRLKNLSEADRQNFFASEEARR
AVHILLIANVSQSYFNQRLAAAQLQVANDTLQNYQQSYAFVEKQLLTGSTTVLALEQARGMIESTRADIAKRQGQLAQAN
NALQLLLGSYQHLPDDSASSAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGAARAAFFPSITLTSSLSGSSS
ELFSLFNAGGAMWNFIPKIELPIFNAGRNQANLDLAEIRQQQQVVNYEQKIQSAFKEVADALAQRQSLADQIAAQQRYLA
SLNITLQRATALYRHGAVSYIEVLSAQRDIFTTRQTLLELNYSRQANEITLFTALGGGWME
>Mature_461_residues
MRSIQLLTLSVIFALTGCLSLAPDYQRPVAPVPQQFSLSQNKLVTAKVGYQETGWRTFFVDPQVKSLISTALTNNRDLRM
ATLKVQEARAQYRVTDADRYPQLNGDGSTTYGGKLKGDTTTSSDYAAGLNLSYDLDFFGRLKNLSEADRQNFFASEEARR
AVHILLIANVSQSYFNQRLAAAQLQVANDTLQNYQQSYAFVEKQLLTGSTTVLALEQARGMIESTRADIAKRQGQLAQAN
NALQLLLGSYQHLPDDSASSAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGAARAAFFPSITLTSSLSGSSS
ELFSLFNAGGAMWNFIPKIELPIFNAGRNQANLDLAEIRQQQQVVNYEQKIQSAFKEVADALAQRQSLADQIAAQQRYLA
SLNITLQRATALYRHGAVSYIEVLSAQRDIFTTRQTLLELNYSRQANEITLFTALGGGWME

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=458, Percent_Identity=75.9825327510917, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI2367348, Length=478, Percent_Identity=24.2677824267782, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50711; Mature: 50711

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIQLLTLSVIFALTGCLSLAPDYQRPVAPVPQQFSLSQNKLVTAKVGYQETGWRTFFV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
DPQVKSLISTALTNNRDLRMATLKVQEARAQYRVTDADRYPQLNGDGSTTYGGKLKGDTT
CHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHEEECCCCCCCCCCCCCCCCCCCEECCCCC
TSSDYAAGLNLSYDLDFFGRLKNLSEADRQNFFASEEARRAVHILLIANVSQSYFNQRLA
CCCCHHCCCCEEECHHHHHHHHCHHHHHHHHCCCCHHHHCEEEEEEEECCHHHHHHHHHH
AAQLQVANDTLQNYQQSYAFVEKQLLTGSTTVLALEQARGMIESTRADIAKRQGQLAQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCHHHHHHHHHHHHCCCHHHHC
NALQLLLGSYQHLPDDSASSAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGA
HHHHHHHHHHHCCCCCCCCCEEEECCEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCH
ARAAFFPSITLTSSLSGSSSELFSLFNAGGAMWNFIPKIELPIFNAGRNQANLDLAEIRQ
HHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHCCCCEECEEEECCCCCCCCCHHHHHH
QQQVVNYEQKIQSAFKEVADALAQRQSLADQIAAQQRYLASLNITLQRATALYRHGAVSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IEVLSAQRDIFTTRQTLLELNYSRQANEITLFTALGGGWME
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRSIQLLTLSVIFALTGCLSLAPDYQRPVAPVPQQFSLSQNKLVTAKVGYQETGWRTFFV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
DPQVKSLISTALTNNRDLRMATLKVQEARAQYRVTDADRYPQLNGDGSTTYGGKLKGDTT
CHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHEEECCCCCCCCCCCCCCCCCCCEECCCCC
TSSDYAAGLNLSYDLDFFGRLKNLSEADRQNFFASEEARRAVHILLIANVSQSYFNQRLA
CCCCHHCCCCEEECHHHHHHHHCHHHHHHHHCCCCHHHHCEEEEEEEECCHHHHHHHHHH
AAQLQVANDTLQNYQQSYAFVEKQLLTGSTTVLALEQARGMIESTRADIAKRQGQLAQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHCCHHHHHHHHHHHHCCCHHHHC
NALQLLLGSYQHLPDDSASSAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGA
HHHHHHHHHHHCCCCCCCCCEEEECCEECCCCCCCCEEECCCCHHHHHHHHHHCCCCCCH
ARAAFFPSITLTSSLSGSSSELFSLFNAGGAMWNFIPKIELPIFNAGRNQANLDLAEIRQ
HHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHCCCCEECEEEECCCCCCCCCHHHHHH
QQQVVNYEQKIQSAFKEVADALAQRQSLADQIAAQQRYLASLNITLQRATALYRHGAVSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IEVLSAQRDIFTTRQTLLELNYSRQANEITLFTALGGGWME
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]