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The map label for this gene is mrkD [H]

Identifier: 238892794

GI number: 238892794

Start: 592494

End: 593447

Strand: Direct

Name: mrkD [H]

Synonym: KP1_0601

Alternate gene names: 238892794

Gene position: 592494-593447 (Clockwise)

Preceding gene: 238892793

Following gene: 238892795

Centisome position: 11.29

GC content: 53.56

Gene sequence:

>954_bases
ATGAAGGTGTTATTAAAATCCGGCTGGCTGGTGCTGGCGTTGTGGCTGGTTTCTTTTGGTACACAGGCCTCCTGTGGTTT
CGCTTCCGGAGTGAGTAGTGAAGTTCCGGGGTATATCAGTTTCGGCAATGTGGCGGTCCAGCGTGATGCGGCGGTGGGCA
GTGTCATCGCCACGGCCACAACGGGGGCGTATAACGGCGGCAATACTATCGCCGGGTGTTCAGAAGCCTGGACCTACCGT
TGGGAACTGAGTAAATGGGGAACGCTGAGCAGTCTCGGAAGCAATATCTATAACACTAATGTTCCTGGAGTGGGTATCCG
GTTGACTAACACCTCTTCCGGGAAAGTGCTTCCCTATGACCAGAGTGTGGGCGCGAATGTTTATATTTACATCGGTGGTG
ATGGTATTAAAGCGGAGTTAATCAAAACGGGCGATATTACGGGAGGAACGCTGGATAGTGGCATGCTGGCGCGGGCCTCG
GTGGCGAACCAGTTTTATTTTGCCAATGTCACCCTGAATGGCACAAATACCATTACCTCTGAATCCTGCTCCGTTACCAC
TAACCCGGTTAATGTCCCGCTGGGTGACCATGACAAAAGCGAGTTCAGCGGTCCGGGTTCCGCAACGGCCTGGCAGACAT
TCAATATCAATCTGAGTTGTATTCAGGGCGCACGGATTAATGTGCGTATTGACGCCACAGCAGATAGCGACGCCGGCGTA
CCCGGCGTCATTAAACTCGACAGCGATCCGGTAAATGCCAGCGGTGTCGGCGTGCAGCTCTGGTACCGCTATGAAGACAG
CCCGGTACAGTTCGGTCAGGAGCGGTATTACTACACCTCGCCATCAGGCGGCAACGAATATGTTCAGCTTCAGGCGCGCT
ATTACCAGACAACACAGAGCATCACGGCCGGGAAAGCGAACGCCACGGCGACGTTTACGTTGACATATAAATAG

Upstream 100 bases:

>100_bases
GGTGAGCTGGAACGGGACGCGGCAGTGCATGGTGCTTTACCGGCTGCCGGAGAATGCCGGAAACGTTCCGGTGACGGAAA
CTGAACAGGAGTGTCGTTAA

Downstream 100 bases:

>100_bases
CTACCTGAACAATTATAAAGGTTTTAGACTAACCCTCTGTTTATCAGGGAAGATGATAATGATCCAATATTGGTGGAAAG
ATCTGTTTGATCGCAATAAT

Product: putative fimbrial adhesin precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKVLLKSGWLVLALWLVSFGTQASCGFASGVSSEVPGYISFGNVAVQRDAAVGSVIATATTGAYNGGNTIAGCSEAWTYR
WELSKWGTLSSLGSNIYNTNVPGVGIRLTNTSSGKVLPYDQSVGANVYIYIGGDGIKAELIKTGDITGGTLDSGMLARAS
VANQFYFANVTLNGTNTITSESCSVTTNPVNVPLGDHDKSEFSGPGSATAWQTFNINLSCIQGARINVRIDATADSDAGV
PGVIKLDSDPVNASGVGVQLWYRYEDSPVQFGQERYYYTSPSGGNEYVQLQARYYQTTQSITAGKANATATFTLTYK

Sequences:

>Translated_317_residues
MKVLLKSGWLVLALWLVSFGTQASCGFASGVSSEVPGYISFGNVAVQRDAAVGSVIATATTGAYNGGNTIAGCSEAWTYR
WELSKWGTLSSLGSNIYNTNVPGVGIRLTNTSSGKVLPYDQSVGANVYIYIGGDGIKAELIKTGDITGGTLDSGMLARAS
VANQFYFANVTLNGTNTITSESCSVTTNPVNVPLGDHDKSEFSGPGSATAWQTFNINLSCIQGARINVRIDATADSDAGV
PGVIKLDSDPVNASGVGVQLWYRYEDSPVQFGQERYYYTSPSGGNEYVQLQARYYQTTQSITAGKANATATFTLTYK
>Mature_317_residues
MKVLLKSGWLVLALWLVSFGTQASCGFASGVSSEVPGYISFGNVAVQRDAAVGSVIATATTGAYNGGNTIAGCSEAWTYR
WELSKWGTLSSLGSNIYNTNVPGVGIRLTNTSSGKVLPYDQSVGANVYIYIGGDGIKAELIKTGDITGGTLDSGMLARAS
VANQFYFANVTLNGTNTITSESCSVTTNPVNVPLGDHDKSEFSGPGSATAWQTFNINLSCIQGARINVRIDATADSDAGV
PGVIKLDSDPVNASGVGVQLWYRYEDSPVQFGQERYYYTSPSGGNEYVQLQARYYQTTQSITAGKANATATFTLTYK

Specific function: Involved In Regulation Of Length And Mediation Of Adhesion Of Type 1 Fimbriae (But Not Necessary For The Production Of Fimbriae). Involved In The Integration Of Fimh In The Fimbriae. [C]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 33465; Mature: 33465

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLKSGWLVLALWLVSFGTQASCGFASGVSSEVPGYISFGNVAVQRDAAVGSVIATAT
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEEEEEE
TGAYNGGNTIAGCSEAWTYRWELSKWGTLSSLGSNIYNTNVPGVGIRLTNTSSGKVLPYD
CCCCCCCCEECCCCCCEEEEEECCCCCCHHHHCCCCEECCCCCEEEEEECCCCCCEEECC
QSVGANVYIYIGGDGIKAELIKTGDITGGTLDSGMLARASVANQFYFANVTLNGTNTITS
CCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEHHHHCCEEEEEEEEECCCCEECC
ESCSVTTNPVNVPLGDHDKSEFSGPGSATAWQTFNINLSCIQGARINVRIDATADSDAGV
CCCEEECCCEECCCCCCCCHHCCCCCCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCC
PGVIKLDSDPVNASGVGVQLWYRYEDSPVQFGQERYYYTSPSGGNEYVQLQARYYQTTQS
CEEEEECCCCCCCCCEEEEEEEEECCCCHHCCCCEEEEECCCCCCEEEEEEEEEEECCCC
ITAGKANATATFTLTYK
EECCCCCCEEEEEEEEC
>Mature Secondary Structure
MKVLLKSGWLVLALWLVSFGTQASCGFASGVSSEVPGYISFGNVAVQRDAAVGSVIATAT
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEEEEEE
TGAYNGGNTIAGCSEAWTYRWELSKWGTLSSLGSNIYNTNVPGVGIRLTNTSSGKVLPYD
CCCCCCCCEECCCCCCEEEEEECCCCCCHHHHCCCCEECCCCCEEEEEECCCCCCEEECC
QSVGANVYIYIGGDGIKAELIKTGDITGGTLDSGMLARASVANQFYFANVTLNGTNTITS
CCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEHHHHCCEEEEEEEEECCCCEECC
ESCSVTTNPVNVPLGDHDKSEFSGPGSATAWQTFNINLSCIQGARINVRIDATADSDAGV
CCCEEECCCEECCCCCCCCHHCCCCCCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCC
PGVIKLDSDPVNASGVGVQLWYRYEDSPVQFGQERYYYTSPSGGNEYVQLQARYYQTTQS
CEEEEECCCCCCCCCEEEEEEEEECCCCHHCCCCEEEEECCCCCCEEEEEEEEEEECCCC
ITAGKANATATFTLTYK
EECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1670938; 2563996 [H]