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The map label for this gene is lpfB [H]

Identifier: 238892792

GI number: 238892792

Start: 589314

End: 589994

Strand: Direct

Name: lpfB [H]

Synonym: KP1_0598

Alternate gene names: 238892792

Gene position: 589314-589994 (Clockwise)

Preceding gene: 238892791

Following gene: 238892793

Centisome position: 11.23

GC content: 59.03

Gene sequence:

>681_bases
ATGAACAGGTATGTACACGTTGCGCTGGCGTTCTTGCTGGCTTTATTTACCGTGCAGGCGCAGGCCGGAATCGTGATTGG
CGGGACGCGGGTGGTTTATGACGGGGATAAAAAAGAGGCCTCAGCGTCCATCCGTAACCCGGAGAAATCCGGCGTTTATC
TGGTGCAGAGCTGGGTGGATAATGGCGAACGGGGCGGCAAAGCGCCGTTTATCGTCACGCCGCCGCTGTTTCGCATTAAC
CCCGGTGAAGAGAATATGCTGCGCATCATTCGCACCGGCGGCAACCTGCCGCCGGACCGGGAGTCGGTGTTCTGGCTCAA
CGTAAAATCCATTCCCGCCACTGATGACAGCAAACCGCACACCAATGTATTGCAGGTAGTGGTGAAGTCGCGCCTGAAGC
TTTTTTACCGACCGGCGGGTCTGGACGGGCATCCGGAGGCCGCATACCGCCAGCTGTCGGTGGCCCGCAGCGGCAATCGC
CTGACTATCAGCAATCCGACGCCGTATTACGTCACGCTGTTCATCCTGAAGGTAGATGGGAAGGAGATAAAGAGTGCGGA
TATGGTGCCGCCGAAGGGCAGTGTGAGTTTCACGATCCCTTCCGCCACGGCGTCCCGCGTTAGCTGGCAGGCCATCAGCG
ACTACGGCGGCGTCAGCCAGTTCGAAAGCCGCCAGCTGTGA

Upstream 100 bases:

>100_bases
TGTGCCGTCGCGGGGCGCATTCTCCTCCTCCTACCCATGCGCCGCCGCATAACAGGGAGCGTTTCGCAGGGATGCGTATT
TTTCGTCCGGAGATAACAAG

Downstream 100 bases:

>100_bases
GGGGAGAGCGTGATGAACAACCCTGAACGGCGCACCATGATGATCCTGCTGGCGCTGCTGCTGGTGATGATCCTCCTGCT
GGCATATTTCCGCAACGCAG

Product: putative fimbrial chaperone protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNRYVHVALAFLLALFTVQAQAGIVIGGTRVVYDGDKKEASASIRNPEKSGVYLVQSWVDNGERGGKAPFIVTPPLFRIN
PGEENMLRIIRTGGNLPPDRESVFWLNVKSIPATDDSKPHTNVLQVVVKSRLKLFYRPAGLDGHPEAAYRQLSVARSGNR
LTISNPTPYYVTLFILKVDGKEIKSADMVPPKGSVSFTIPSATASRVSWQAISDYGGVSQFESRQL

Sequences:

>Translated_226_residues
MNRYVHVALAFLLALFTVQAQAGIVIGGTRVVYDGDKKEASASIRNPEKSGVYLVQSWVDNGERGGKAPFIVTPPLFRIN
PGEENMLRIIRTGGNLPPDRESVFWLNVKSIPATDDSKPHTNVLQVVVKSRLKLFYRPAGLDGHPEAAYRQLSVARSGNR
LTISNPTPYYVTLFILKVDGKEIKSADMVPPKGSVSFTIPSATASRVSWQAISDYGGVSQFESRQL
>Mature_226_residues
MNRYVHVALAFLLALFTVQAQAGIVIGGTRVVYDGDKKEASASIRNPEKSGVYLVQSWVDNGERGGKAPFIVTPPLFRIN
PGEENMLRIIRTGGNLPPDRESVFWLNVKSIPATDDSKPHTNVLQVVVKSRLKLFYRPAGLDGHPEAAYRQLSVARSGNR
LTISNPTPYYVTLFILKVDGKEIKSADMVPPKGSVSFTIPSATASRVSWQAISDYGGVSQFESRQL

Specific function: Required for the biogenesis of long polar fimbria; binds and interact with lpfA [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=212, Percent_Identity=41.9811320754717, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789532, Length=227, Percent_Identity=43.1718061674009, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1786743, Length=218, Percent_Identity=38.9908256880734, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1787171, Length=217, Percent_Identity=39.1705069124424, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI87081806, Length=234, Percent_Identity=35.042735042735, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786333, Length=238, Percent_Identity=34.8739495798319, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788428, Length=215, Percent_Identity=32.5581395348837, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786936, Length=218, Percent_Identity=32.5688073394495, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082203, Length=237, Percent_Identity=29.957805907173, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1788677, Length=151, Percent_Identity=35.7615894039735, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24803; Mature: 24803

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYVHVALAFLLALFTVQAQAGIVIGGTRVVYDGDKKEASASIRNPEKSGVYLVQSWVD
CCCCHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHCCCCCCCCCCCCEEEEEEECC
NGERGGKAPFIVTPPLFRINPGEENMLRIIRTGGNLPPDRESVFWLNVKSIPATDDSKPH
CCCCCCCCCEEECCCEEEECCCHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCH
TNVLQVVVKSRLKLFYRPAGLDGHPEAAYRQLSVARSGNRLTISNPTPYYVTLFILKVDG
HHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECC
KEIKSADMVPPKGSVSFTIPSATASRVSWQAISDYGGVSQFESRQL
CCCCCCCCCCCCCCEEEEECCCCCHHEEHEEHHCCCCCCCHHCCCC
>Mature Secondary Structure
MNRYVHVALAFLLALFTVQAQAGIVIGGTRVVYDGDKKEASASIRNPEKSGVYLVQSWVD
CCCCHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHCCCCCCCCCCCCEEEEEEECC
NGERGGKAPFIVTPPLFRINPGEENMLRIIRTGGNLPPDRESVFWLNVKSIPATDDSKPH
CCCCCCCCCEEECCCEEEECCCHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCH
TNVLQVVVKSRLKLFYRPAGLDGHPEAAYRQLSVARSGNRLTISNPTPYYVTLFILKVDG
HHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEECC
KEIKSADMVPPKGSVSFTIPSATASRVSWQAISDYGGVSQFESRQL
CCCCCCCCCCCCCCEEEEECCCCCHHEEHEEHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721701; 11677609 [H]