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The map label for this gene is cysQ [H]

Identifier: 238892693

GI number: 238892693

Start: 479422

End: 480165

Strand: Direct

Name: cysQ [H]

Synonym: KP1_0484

Alternate gene names: 238892693

Gene position: 479422-480165 (Clockwise)

Preceding gene: 238892691

Following gene: 238892695

Centisome position: 9.13

GC content: 59.54

Gene sequence:

>744_bases
ATGTTAGAACAAGTATGTCAGCTTGCACGGAATGCGGGCGATGCCATCATGGAAGTCTACGATGGAAACCAGCCGATCAA
CGTCGCCAGCAAGAAAGATGATTCTCCGGTCACGGCGGCGGATATCGCAGCGCATAAAGTCATTGTCAGCGGCCTGCAGG
CGCTGGATCCGGATACCCCGATCCTCTCCGAGGAGGACCCGCCGTCCTGGGAAGTGCGCCAGCACTGGCAGCGCTACTGG
CTGGTCGACCCGCTGGACGGCACCAAAGAGTTTATTAAGCGTAACGGCGAATTCACCGTCAATATCGCGCTGATTGAAAA
CGGCAAGCCGACGCTGGGCGTTGTCTATGCGCCGGTGATGAAGGTGATGTACAGCGCGCAAAATGGTAAAGCCTGGAAAG
AAGAGTGTGGCGTACGCAAGCAGATCCAGGTCCGCGATGCCCGTCCGCCGCTGGTGGTGATTAGCCGCTCCCACAGCAAC
GATCCGGAGCTGCAGGAGTATCTTGAGCAACTGGGCGAACACCAGACCACCTCAATCGGTTCGTCGCTGAAATTCTGCCT
GGTGGCGGAAGGTCAGGCCCAGCTCTATCCGCGCTTCGGGCCGACCAGCACCTGGGACACCGCCGCCGGCCATGCGGTCG
CGGTGGCCGCCGGGGCGCATGTTCACGACTGGCAGGGGAAAACCCTCGACTACACGCCGCGTGAATCCTTCCTTAACCCC
GGCTTCCGGGTCTCTATTTATTAA

Upstream 100 bases:

>100_bases
GCAGAGAAACCGCCATCGTTATCACAGATAGCGGAACTCGCGGTGATGCGATATAAATAAAACAACGAGTTAACGCCACT
GTAACCAGACGAGGTGGAGA

Downstream 100 bases:

>100_bases
GCAATTTATGCAGCAGGTCGATCACCTGCTGCACCTCTTGTTGGGTGAGGGCGCCGTCTTTAGCCCACTGCACACGCCCG
TTCTTATCCAGCACCACGAT

Product: adenosine-3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLEQVCQLARNAGDAIMEVYDGNQPINVASKKDDSPVTAADIAAHKVIVSGLQALDPDTPILSEEDPPSWEVRQHWQRYW
LVDPLDGTKEFIKRNGEFTVNIALIENGKPTLGVVYAPVMKVMYSAQNGKAWKEECGVRKQIQVRDARPPLVVISRSHSN
DPELQEYLEQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTSTWDTAAGHAVAVAAGAHVHDWQGKTLDYTPRESFLNP
GFRVSIY

Sequences:

>Translated_247_residues
MLEQVCQLARNAGDAIMEVYDGNQPINVASKKDDSPVTAADIAAHKVIVSGLQALDPDTPILSEEDPPSWEVRQHWQRYW
LVDPLDGTKEFIKRNGEFTVNIALIENGKPTLGVVYAPVMKVMYSAQNGKAWKEECGVRKQIQVRDARPPLVVISRSHSN
DPELQEYLEQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTSTWDTAAGHAVAVAAGAHVHDWQGKTLDYTPRESFLNP
GFRVSIY
>Mature_247_residues
MLEQVCQLARNAGDAIMEVYDGNQPINVASKKDDSPVTAADIAAHKVIVSGLQALDPDTPILSEEDPPSWEVRQHWQRYW
LVDPLDGTKEFIKRNGEFTVNIALIENGKPTLGVVYAPVMKVMYSAQNGKAWKEECGVRKQIQVRDARPPLVVISRSHSN
DPELQEYLEQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTSTWDTAAGHAVAVAAGAHVHDWQGKTLDYTPRESFLNP
GFRVSIY

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=29.5081967213115, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5031789, Length=238, Percent_Identity=30.2521008403361, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7657236, Length=236, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790659, Length=247, Percent_Identity=86.6396761133603, Blast_Score=419, Evalue=1e-119,
Organism=Escherichia coli, GI1788882, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71995905, Length=266, Percent_Identity=27.0676691729323, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=266, Percent_Identity=27.0676691729323, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357303, Length=240, Percent_Identity=27.9166666666667, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641722, Length=269, Percent_Identity=26.7657992565056, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27369; Mature: 27369

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQVCQLARNAGDAIMEVYDGNQPINVASKKDDSPVTAADIAAHKVIVSGLQALDPDTP
CHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ILSEEDPPSWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNIALIENGKPTLGVVYAPVM
CCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHHHH
KVMYSAQNGKAWKEECGVRKQIQVRDARPPLVVISRSHSNDPELQEYLEQLGEHQTTSIG
HHHHHCCCCCHHHHHCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHC
SSLKFCLVAEGQAQLYPRFGPTSTWDTAAGHAVAVAAGAHVHDWQGKTLDYTPRESFLNP
CCEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCHHHHCCC
GFRVSIY
CEEEEEC
>Mature Secondary Structure
MLEQVCQLARNAGDAIMEVYDGNQPINVASKKDDSPVTAADIAAHKVIVSGLQALDPDTP
CHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ILSEEDPPSWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNIALIENGKPTLGVVYAPVM
CCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHHHH
KVMYSAQNGKAWKEECGVRKQIQVRDARPPLVVISRSHSNDPELQEYLEQLGEHQTTSIG
HHHHHCCCCCHHHHHCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHC
SSLKFCLVAEGQAQLYPRFGPTSTWDTAAGHAVAVAAGAHVHDWQGKTLDYTPRESFLNP
CCEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCHHHHCCC
GFRVSIY
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]