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The map label for this gene is actP

Identifier: 238892565

GI number: 238892565

Start: 349938

End: 351593

Strand: Reverse

Name: actP

Synonym: KP1_0340

Alternate gene names: 238892565

Gene position: 351593-349938 (Counterclockwise)

Preceding gene: 238892566

Following gene: 238892557

Centisome position: 6.7

GC content: 59.24

Gene sequence:

>1656_bases
ATGATCAAGAGAGTCCTGACGGCGCTCGCCGCCACGCTGCTGCCCCTCGGCGCTCACGCCGCAGACGCTATTACCGGCGC
GGTACAGCGCCAGCCGACCAACTGGCAGGCGATTGTCATGTTCCTGATTTTCGTTGCCCTGACGCTGTACATCACCTACT
GGGCCTCAAAACGGGTGCGTTCGCGCAGCGATTACTACACCGCCGGCGGCAATATTACCGGCTTCCAGAACGGGCTGGCG
ATTGCCGGCGACTTTATGTCAGCGGCGTCGTTCCTCGGTATCTCCGCGCTGGTGTATACCTCCGGCTACGATGGGCTGAT
CTACTCGCTGGGCTTTCTCGTCGGCTGGCCGATTATCCTGTTTCTAATTGCTGAACGTCTGCGCAATCTTGGCCGCTATA
CTTTTGCCGATGTCGCCTCTTACCGCCTGAAGCAGGGGCCGATCCGCACCCTCTCCGCCTGCGGTTCGCTGGTGGTGGTG
GCCCTGTATCTGATTGCCCAGATGGTGGGCGCCGGCAAGCTGATCCAGCTGCTGTTCGGCCTTAATTACCATGTCGCCGT
AGTGCTGGTTGGCGTGCTGATGGTGCTCTATGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTGCAGATTATTAAAG
CGGTTCTGCTGCTGTGCGGCGCCAGTTTTATGGCCTTTATGGTCATGAAGCACGTCGGCTTCAGCTTCAATAACCTGTTT
ACCGAGGCGATGGCGGTCCACCCGAAAGGGGCGGCGATTATGAGTCCCGGCGGACTGGTGAAAGATCCGATATCCGCGCT
CTCTCTGGGTCTGGGTCTGATGTTCGGTACCGCTGGCCTGCCGCATATTCTGATGCGCTTCTTTACCGTGAGCGACGCCA
AAGAAGCACGTAAAAGCGTCTTCTACGCCACCGGTTTTATGGGCTATTTCTATATCCTGACCTTTATCATCGGCTTCGGC
GCCATCATGCTGGTCGGCGCGAACCCGGCGTTTAAAGACGCGGCCGGACAGCTTATCGGCGGCAATAACATGGCGGCGGT
GCACCTGGCGGATGCGGTTGGCGGCAACCTGTTCCTCGGGTTTATCTCTGCGGTAGCCTTCGCCACTATCCTGGCGGTGG
TGGCGGGCCTGACCCTCGCCGGCGCGTCAGCGGTGTCGCACGACCTGTACGCCAACGTCTTCCGCAAGGGCGCGACCGAG
CGTCAGGAGCTGAAGGTCTCCAAGATCACCGTACTGATCCTTGGGGTGGTGGCCATTCTGCTGGGTATTCTGTTTGAAAA
TCAGAACATTGCTTTCATGGTCGGCCTGGCCTTCTCCATCGCCGCCAGCTGTAACTTCCCGATTATTCTGCTGTCGATGT
ACTGGTCGAAGCTGACCACCCGCGGCGCGATGGTCGGCGGCTGGCTGGGCCTGCTGACTGCGGTCATTCTGATGATCCTC
GGTCCTACCATTTGGGTGCAGATCCTCGGCCATGAGAAAGCGCTGTTCCCGTATGAATATCCGGCGCTGTTCTCCATTGC
CATCGCGTTCATTGGCATCTGGGTCTTCTCCGCCACCGATAACTCACCGGAAGGGATGCGCGAGCGCGAGCAGTTCCGCG
CCCAGTTTATCCGTTCACAAACCGGGATCGGTATCGAACGCGGCCAGGCGCATTAA

Upstream 100 bases:

>100_bases
GCGTGATCGTCATTTCGTTTATCCTGACCGGTATTTATGTCTGGCGAGCTAACGGTGAATTCGACCGTTTGACCAAAAGC
GTTCTCAACGAGGTAAAAGC

Downstream 100 bases:

>100_bases
TCGTCTTCTCCCTTCCCCGGCATCGTTCGGGGAAGGGATTCTCCCCTCAGTTATAAGTAAAGGTGATCACCCCGGTGGCG
TTGGCTGTCCCCGCGGTCAC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLA
IAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVV
ALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFG
AIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATE
RQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH

Sequences:

>Translated_551_residues
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLA
IAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVV
ALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFG
AIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATE
RQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH
>Mature_551_residues
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVRSRSDYYTAGGNITGFQNGLA
IAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVV
ALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFMGYFYILTFIIGFG
AIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATE
RQELKVSKITVLILGVVAILLGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQTGIGIERGQAH

Specific function: Transports acetate

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family

Homologues:

Organism=Homo sapiens, GI310128183, Length=514, Percent_Identity=24.7081712062257, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790503, Length=550, Percent_Identity=90.9090909090909, Blast_Score=1010, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=508, Percent_Identity=24.8031496062992, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACTP_KLEP3 (B5XXT7)

Other databases:

- EMBL:   CP000964
- RefSeq:   YP_002240964.1
- GeneID:   6939610
- GenomeReviews:   CP000964_GR
- KEGG:   kpe:KPK_5193
- HOGENOM:   HBG533958
- OMA:   LYASVWR
- ProtClustDB:   PRK09395
- HAMAP:   MF_01426
- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900
- PANTHER:   PTHR11819
- TIGRFAMs:   TIGR00813
- TIGRFAMs:   TIGR02711

Pfam domain/function: PF00474 SSF

EC number: NA

Molecular weight: Translated: 59126; Mature: 59126

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00456 NA_SOLUT_SYMP_1; PS00457 NA_SOLUT_SYMP_2; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x184750ac)-; HASH(0x18417a88)-; HASH(0x16695d2c)-; HASH(0x1905b9b4)-; HASH(0x18e960f0)-; HASH(0x18f455f4)-; HASH(0x19003d2c)-; HASH(0x18fb8afc)-; HASH(0x18bd7a5c)-; HASH(0x1903ac88)-; HASH(0x18c66ffc)-; HASH(0x18cab048)-; HASH(0x185bdb10)-; HASH(0x1871c004)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRVLTALAATLLPLGAHAADAITGAVQRQPTNWQAIVMFLIFVALTLYITYWASKRVR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRSDYYTAGGNITGFQNGLAIAGDFMSAASFLGISALVYTSGYDGLIYSLGFLVGWPIIL
CCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FLIAERLRNLGRYTFADVASYRLKQGPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFG
HHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
LNYHVAVVLVGVLMVLYVLFGGMLATTWVQIIKAVLLLCGASFMAFMVMKHVGFSFNNLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TEAMAVHPKGAAIMSPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAKEARKSV
HHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
FYATGFMGYFYILTFIIGFGAIMLVGANPAFKDAAGQLIGGNNMAAVHLADAVGGNLFLG
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCEECCCCEEEEEEHHHCCHHHHHH
FISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATERQELKVSKITVLILGVVAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LGILFENQNIAFMVGLAFSIAASCNFPIILLSMYWSKLTTRGAMVGGWLGLLTAVILMIL
HHHHHCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GPTIWVQILGHEKALFPYEYPALFSIAIAFIGIWVFSATDNSPEGMREREQFRAQFIRSQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
TGIGIERGQAH
CCCCCCCCCCH
>Mature Secondary Structure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CCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA