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The map label for this gene is ywbI [H]

Identifier: 238892557

GI number: 238892557

Start: 341756

End: 342637

Strand: Reverse

Name: ywbI [H]

Synonym: KP1_0330

Alternate gene names: 238892557

Gene position: 342637-341756 (Counterclockwise)

Preceding gene: 238892565

Following gene: 238892552

Centisome position: 6.53

GC content: 59.52

Gene sequence:

>882_bases
ATGGATATCCGAACGCTGCGCTATTTCGTTGAAGTGGTTCGTCAGCAGAGTTTTACTCGCGCGGCGGAAAAGCTGTTTGT
CACACAGCCCACCATCAGCAAGATGCTCAAGAATCTCGAAGATGAGCTGAACTGCACGCTGTTGATCCGCGACGGCCGCA
AACTGCTGCTCACCGATACCGGGCGCGTCGTCTTTGAACGCGGCCAGGCGATCTTGGGCGAGTTCAGCCAGCTGGAGTCA
GAGCTGAGCGATATCAATCACCTGCATAAAGGGGTGCTGCGGCTTGGCATTCCGCCGATGGTCGGGATGCTGATGGCCGA
GCCGATCAGTCGCTTCCGCCAGCGCTATCCGGGCGTCGAGCTGAAGATCGCCGAGTTTGGCGGCCTGACGGTCCAGCAGG
CGGTCAGCAATGGCGAACTTGATATGGCGATGACCGCCCTGCCTGTCGAGGAGGATAGCAGCCTCACCATTCTGCCGTTG
TTCAATCACCCGCTGTGCGTCCTGACGCCAAGGACCGCGGAGTGGGAAGGTAAAACCTCGCTCTCGCCGGCCGAGCTGGC
GTCGCATCCGCTGGTTATCTACAACGAGGAATTTGCCCTTAGCCAGCAGCTGATGCGGCTGTTTGCCGAGCATGACGTGA
AGCCACGTATCGCAGTGCGCAGCGGCCAGTGGGATTTTCTCGCCGCCATGGTGCAGGCGGGCATTGGCGTAGCGATCCTG
CCGGAACCGATTTGCCAGCGTCTCGACCGGCAGAATTTTTGCTGGATCCCGTTGCAAAGCGAGCTGCGCTGGGAGCTGGG
GATGATTTGGCGGGAAGGCGTATATATGTCGCGCAGCGCTGAAGCCTGGCTGACGTGCAGCAAAGCGTTCTGGCTGGAAT
AA

Upstream 100 bases:

>100_bases
ATAGTCCTGAAAAAAAGAAGTCAGGCGAGCAGTATAGAGAGCCGCCGAAGCGGACAGAAATGAATTAAAATCATCGCAGG
TATAGTCTCAGGGAATAATT

Downstream 100 bases:

>100_bases
TTCTCTGGTGACAACGCGTTCCGCAAGGGAAGGGGTAGCCCGGGTCAGGCGCTTGCGCCGCTGCCCGGGTTTCCCCCGGT
CGCGCTAACGCTTACCGGGG

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGQAILGEFSQLES
ELSDINHLHKGVLRLGIPPMVGMLMAEPISRFRQRYPGVELKIAEFGGLTVQQAVSNGELDMAMTALPVEEDSSLTILPL
FNHPLCVLTPRTAEWEGKTSLSPAELASHPLVIYNEEFALSQQLMRLFAEHDVKPRIAVRSGQWDFLAAMVQAGIGVAIL
PEPICQRLDRQNFCWIPLQSELRWELGMIWREGVYMSRSAEAWLTCSKAFWLE

Sequences:

>Translated_293_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGQAILGEFSQLES
ELSDINHLHKGVLRLGIPPMVGMLMAEPISRFRQRYPGVELKIAEFGGLTVQQAVSNGELDMAMTALPVEEDSSLTILPL
FNHPLCVLTPRTAEWEGKTSLSPAELASHPLVIYNEEFALSQQLMRLFAEHDVKPRIAVRSGQWDFLAAMVQAGIGVAIL
PEPICQRLDRQNFCWIPLQSELRWELGMIWREGVYMSRSAEAWLTCSKAFWLE
>Mature_293_residues
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDTGRVVFERGQAILGEFSQLES
ELSDINHLHKGVLRLGIPPMVGMLMAEPISRFRQRYPGVELKIAEFGGLTVQQAVSNGELDMAMTALPVEEDSSLTILPL
FNHPLCVLTPRTAEWEGKTSLSPAELASHPLVIYNEEFALSQQLMRLFAEHDVKPRIAVRSGQWDFLAAMVQAGIGVAIL
PEPICQRLDRQNFCWIPLQSELRWELGMIWREGVYMSRSAEAWLTCSKAFWLE

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=28.9855072463768, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=28.3582089552239, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI157672245, Length=251, Percent_Identity=26.2948207171315, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787530, Length=245, Percent_Identity=28.9795918367347, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693105, Length=303, Percent_Identity=24.4224422442244, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788887, Length=276, Percent_Identity=25.7246376811594, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789506, Length=295, Percent_Identity=21.6949152542373, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786401, Length=244, Percent_Identity=31.9672131147541, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.8683127572016, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=262, Percent_Identity=22.9007633587786, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367136, Length=273, Percent_Identity=23.4432234432234, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787601, Length=261, Percent_Identity=24.5210727969349, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789639, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787806, Length=289, Percent_Identity=22.4913494809689, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789173, Length=198, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788481, Length=241, Percent_Identity=23.2365145228216, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=290, Percent_Identity=23.7931034482759, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693193, Length=126, Percent_Identity=30.1587301587302, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=23.3333333333333, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=25.6198347107438, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=93, Percent_Identity=36.5591397849462, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082132, Length=253, Percent_Identity=26.4822134387352, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33317; Mature: 33317

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
GRVVFERGQAILGEFSQLESELSDINHLHKGVLRLGIPPMVGMLMAEPISRFRQRYPGVE
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
LKIAEFGGLTVQQAVSNGELDMAMTALPVEEDSSLTILPLFNHPLCVLTPRTAEWEGKTS
EEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCC
LSPAELASHPLVIYNEEFALSQQLMRLFAEHDVKPRIAVRSGQWDFLAAMVQAGIGVAIL
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PEPICQRLDRQNFCWIPLQSELRWELGMIWREGVYMSRSAEAWLTCSKAFWLE
CHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCEEECCCCCHHEEECHHHCCC
>Mature Secondary Structure
MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECC
GRVVFERGQAILGEFSQLESELSDINHLHKGVLRLGIPPMVGMLMAEPISRFRQRYPGVE
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCE
LKIAEFGGLTVQQAVSNGELDMAMTALPVEEDSSLTILPLFNHPLCVLTPRTAEWEGKTS
EEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCC
LSPAELASHPLVIYNEEFALSQQLMRLFAEHDVKPRIAVRSGQWDFLAAMVQAGIGVAIL
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PEPICQRLDRQNFCWIPLQSELRWELGMIWREGVYMSRSAEAWLTCSKAFWLE
CHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCEEECCCCCHHEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]