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The map label for this gene is qor [H]

Identifier: 238892524

GI number: 238892524

Start: 305743

End: 306726

Strand: Reverse

Name: qor [H]

Synonym: KP1_0293

Alternate gene names: 238892524

Gene position: 306726-305743 (Counterclockwise)

Preceding gene: 238892531

Following gene: 238892519

Centisome position: 5.84

GC content: 59.55

Gene sequence:

>984_bases
ATGGCAACACGCATCGAATTTTCGAAACACGGGGGACCGGAGGTGCTTCAGGCGGTTGAGTTCACGCCACGCGATCCCGC
AGAACATGAGATTCAGGTCGAAAACAAAGCCATCGGCATCAACTATATCGACACCTATGTTCGCAGCGGCCTTTATCCGC
CGCCGTCGCTGCCGAGCGGCCTGGGCACCGAGGCGGCCGGCATCGTCAGTAAAGTTGGCCATGGGGTCACGCATATTAAG
GTAGGCGATCGGGTGGTGTACGCCCAGTCGGCGCTCGGCGCCTACAGCACGGTACACAATGTGCTGGCCGACAAAGCGGC
GGTCCTGCCGGACGCTATCTCTTTCGAACAGGCCGCCGCGTCGTTCCTCAAAGGATTAACGGTCTGGTATCTGCTGCGCA
AAACCTATGAAATTAAGCCTGATGAGATGTTCCTGTTTCACGCGGCCGCTGGCGGCGTGGGGCTGATAGCCTGTCAGTGG
GCGAAAGCGCTGGGGGCGAAACTTATCGGTACCGTCGGCAGCGCGCAGAAAGCGCAGCGCGCCAAAGAGGCGGGCGCCTG
GCAGGTGATTAACTATCGCGAGGAGTCTATCGTGGAGCGGCTCAAGGCGCTCACCGACGGTAAGAAAGTGGCCGTCGTCT
ACGACTCGGTGGGGAAAGATACCTGGGAGGCCTCTCTGGACTGCCTGCAGCGCCGCGGCCTGATGGTCAGCTTTGGTAAC
TCCTCCGGTCCGGTGACCGGCGTTAATCTGGGGATCCTGAATCAAAAAGGCTCCCTGTACGTCACTCGCCCATCGCTGCA
GGGCTATATCACCAACCGGGAAGAACTGGAGGAAGCCTGCAGTGAACTGTTTTCGCTGATCGCCAGCGGGGTGATTAAAG
TGGACGTGGCTGAAAGTCAGATCTATCCGCTGAGCGAAGCGCGGCGGGCGCATGAAGTTCTGGAGAGCCGGGTGACGCAG
GGTTCGAGTTTGCTGCTGCCATAA

Upstream 100 bases:

>100_bases
CCATTAAGCGTGGCAGGCCTGAGGCGGGTAAGAAAATCCGTCGCCGCCGGCGCAGGCTGTTAAGCTTACTGAATAATCTC
GGAACAACACAGGAGCGAAC

Downstream 100 bases:

>100_bases
GTTGGCAGAAGGGGCAAAAGTTTAGGGCTTCCACCTGGGAAGCCCTTACTTTTTTTTAGTTCGGCTGTATGTAGGGTACA
GCGCGATGAATTCGTTAACG

Product: quinone oxidoreductase, NADPH-dependent

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MATRIEFSKHGGPEVLQAVEFTPRDPAEHEIQVENKAIGINYIDTYVRSGLYPPPSLPSGLGTEAAGIVSKVGHGVTHIK
VGDRVVYAQSALGAYSTVHNVLADKAAVLPDAISFEQAAASFLKGLTVWYLLRKTYEIKPDEMFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSAQKAQRAKEAGAWQVINYREESIVERLKALTDGKKVAVVYDSVGKDTWEASLDCLQRRGLMVSFGN
SSGPVTGVNLGILNQKGSLYVTRPSLQGYITNREELEEACSELFSLIASGVIKVDVAESQIYPLSEARRAHEVLESRVTQ
GSSLLLP

Sequences:

>Translated_327_residues
MATRIEFSKHGGPEVLQAVEFTPRDPAEHEIQVENKAIGINYIDTYVRSGLYPPPSLPSGLGTEAAGIVSKVGHGVTHIK
VGDRVVYAQSALGAYSTVHNVLADKAAVLPDAISFEQAAASFLKGLTVWYLLRKTYEIKPDEMFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSAQKAQRAKEAGAWQVINYREESIVERLKALTDGKKVAVVYDSVGKDTWEASLDCLQRRGLMVSFGN
SSGPVTGVNLGILNQKGSLYVTRPSLQGYITNREELEEACSELFSLIASGVIKVDVAESQIYPLSEARRAHEVLESRVTQ
GSSLLLP
>Mature_326_residues
ATRIEFSKHGGPEVLQAVEFTPRDPAEHEIQVENKAIGINYIDTYVRSGLYPPPSLPSGLGTEAAGIVSKVGHGVTHIKV
GDRVVYAQSALGAYSTVHNVLADKAAVLPDAISFEQAAASFLKGLTVWYLLRKTYEIKPDEMFLFHAAAGGVGLIACQWA
KALGAKLIGTVGSAQKAQRAKEAGAWQVINYREESIVERLKALTDGKKVAVVYDSVGKDTWEASLDCLQRRGLMVSFGNS
SGPVTGVNLGILNQKGSLYVTRPSLQGYITNREELEEACSELFSLIASGVIKVDVAESQIYPLSEARRAHEVLESRVTQG
SSLLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=30, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=30, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=30.8157099697885, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=30.8157099697885, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI194239676, Length=197, Percent_Identity=35.0253807106599, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=27.8481012658228, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI28557745, Length=304, Percent_Identity=28.6184210526316, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24308257, Length=238, Percent_Identity=28.1512605042017, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI67078404, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI67078406, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=87.7675840978593, Blast_Score=592, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17507255, Length=258, Percent_Identity=31.7829457364341, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536829, Length=296, Percent_Identity=28.3783783783784, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=319, Percent_Identity=37.9310344827586, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324486, Length=320, Percent_Identity=25.3125, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550423, Length=318, Percent_Identity=25.4716981132075, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35200; Mature: 35068

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRIEFSKHGGPEVLQAVEFTPRDPAEHEIQVENKAIGINYIDTYVRSGLYPPPSLPSG
CCCEECCCCCCCHHHHHHHCCCCCCCCCCEEEECCCEEEHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGHGVTHIKVGDRVVYAQSALGAYSTVHNVLADKAAVLPDAISFEQAAA
CCCHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SFLKGLTVWYLLRKTYEIKPDEMFLFHAAAGGVGLIACQWAKALGAKLIGTVGSAQKAQR
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
AKEAGAWQVINYREESIVERLKALTDGKKVAVVYDSVGKDTWEASLDCLQRRGLMVSFGN
HHHCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECC
SSGPVTGVNLGILNQKGSLYVTRPSLQGYITNREELEEACSELFSLIASGVIKVDVAESQ
CCCCEEEEEEEEEECCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEECCCC
IYPLSEARRAHEVLESRVTQGSSLLLP
CCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATRIEFSKHGGPEVLQAVEFTPRDPAEHEIQVENKAIGINYIDTYVRSGLYPPPSLPSG
CCEECCCCCCCHHHHHHHCCCCCCCCCCEEEECCCEEEHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGHGVTHIKVGDRVVYAQSALGAYSTVHNVLADKAAVLPDAISFEQAAA
CCCHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SFLKGLTVWYLLRKTYEIKPDEMFLFHAAAGGVGLIACQWAKALGAKLIGTVGSAQKAQR
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
AKEAGAWQVINYREESIVERLKALTDGKKVAVVYDSVGKDTWEASLDCLQRRGLMVSFGN
HHHCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECC
SSGPVTGVNLGILNQKGSLYVTRPSLQGYITNREELEEACSELFSLIASGVIKVDVAESQ
CCCCEEEEEEEEEECCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEECCCC
IYPLSEARRAHEVLESRVTQGSSLLLP
CCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]