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The map label for this gene is zur [H]

Identifier: 238892519

GI number: 238892519

Start: 302826

End: 303347

Strand: Reverse

Name: zur [H]

Synonym: KP1_0287

Alternate gene names: 238892519

Gene position: 303347-302826 (Counterclockwise)

Preceding gene: 238892524

Following gene: 238892517

Centisome position: 5.78

GC content: 56.9

Gene sequence:

>522_bases
ATGCTCATGGATAAGACCCCTTCGCAAGAGATGTTAGCGCATGCTGAAAAGCTTTGCGCACAGCGCGGCGTACGCCTGAC
TCCACAGCGTCTGGAAGTGTTGCGCCTGATGAGCCTGCAGCAAGGGGCAATCAGCGCCTACGATCTGCTGGACTTGCTAC
GTGAAAAAGAGCCGCAGGCGAAGCCGCCGACGGTTTACCGTGCGCTGGAGTTTTTACTCGAGCAGGGTTTTGTCCATAAG
GTAGAGTCAACCAATAGCTATGTGCTGTGCCATCTGTTCGACCAGCCGACCCATAGCTCGGCCATGTTTATCTGCGACCG
CTGCGGCGTGGTAAAAGAAGAAGCGGCGGAAGGGGTGGAAGATATCATGCATACGCTGGCGGCCCGCATGGGGTTTGCCC
TGCGCCACAATGTGATAGAAGCTCACGGGCTTTGCGCGGGCTGCGTGGAAGTCGAAGCCTGCAGCACCCCGGGACACTGC
CAGCACGATCATACTATTCAGCTCAAAAAGAAAGCCCGCTGA

Upstream 100 bases:

>100_bases
GGTGCCGACAACCTGAAGTATGACCCGTATCACCTGCCGGCTCTCGGTGTTTTCTGAGGAACGTGATAAAGTAACAGATT
CAAATTCACGCAATCCGAGG

Downstream 100 bases:

>100_bases
GCGGCTGCCGCAGCGGGAAAAGGGTTAACGGCGCGTCCCTGCGCCATTCAGACAGGCACTAACACAAATGCTTCATTCTT
CGGATCAAGGAACGCTACCA

Product: zinc uptake transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLMDKTPSQEMLAHAEKLCAQRGVRLTPQRLEVLRLMSLQQGAISAYDLLDLLREKEPQAKPPTVYRALEFLLEQGFVHK
VESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEEAAEGVEDIMHTLAARMGFALRHNVIEAHGLCAGCVEVEACSTPGHC
QHDHTIQLKKKAR

Sequences:

>Translated_173_residues
MLMDKTPSQEMLAHAEKLCAQRGVRLTPQRLEVLRLMSLQQGAISAYDLLDLLREKEPQAKPPTVYRALEFLLEQGFVHK
VESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEEAAEGVEDIMHTLAARMGFALRHNVIEAHGLCAGCVEVEACSTPGHC
QHDHTIQLKKKAR
>Mature_173_residues
MLMDKTPSQEMLAHAEKLCAQRGVRLTPQRLEVLRLMSLQQGAISAYDLLDLLREKEPQAKPPTVYRALEFLLEQGFVHK
VESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEEAAEGVEDIMHTLAARMGFALRHNVIEAHGLCAGCVEVEACSTPGHC
QHDHTIQLKKKAR

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=171, Percent_Identity=86.5497076023392, Blast_Score=311, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19365; Mature: 19365

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMDKTPSQEMLAHAEKLCAQRGVRLTPQRLEVLRLMSLQQGAISAYDLLDLLREKEPQA
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
KPPTVYRALEFLLEQGFVHKVESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEEAAEGVE
CCCHHHHHHHHHHHCCHHEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHH
DIMHTLAARMGFALRHNVIEAHGLCAGCVEVEACSTPGHCQHDHTIQLKKKAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MLMDKTPSQEMLAHAEKLCAQRGVRLTPQRLEVLRLMSLQQGAISAYDLLDLLREKEPQA
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
KPPTVYRALEFLLEQGFVHKVESTNSYVLCHLFDQPTHSSAMFICDRCGVVKEEAAEGVE
CCCHHHHHHHHHHHCCHHEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHH
DIMHTLAARMGFALRHNVIEAHGLCAGCVEVEACSTPGHCQHDHTIQLKKKAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]