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The map label for this gene is ubiA [H]

Identifier: 238892512

GI number: 238892512

Start: 296335

End: 297201

Strand: Direct

Name: ubiA [H]

Synonym: KP1_0280

Alternate gene names: 238892512

Gene position: 296335-297201 (Clockwise)

Preceding gene: 238892511

Following gene: 238892514

Centisome position: 5.65

GC content: 59.86

Gene sequence:

>867_bases
ATGGAGTGGAGTCTGTCGCAGAATAAGCTGTTGGCGTTTCATCGCCTGATGCGCACTGACAAACCGATCGGCGCTTTGCT
GCTGCTGTGGCCGACGCTGTGGGCGCTATGGGTGGCCTCGCCGGGCGTCCCGCCGTTGTGGATCCTGGCGGTATTCGTCG
CCGGCGTCTGGCTGATGCGCGCCGCCGGCTGCGTGGTGAATGACTATGCCGACCGAAAATTTGATGGTCACGTAAAGCGT
ACCGCCCGCCGTCCGCTGCCGAGCGGCGATGTTACCGAGAAAGAGGCGCGAACGCTGTTTATCGTGCTGGTGCTGCTCTC
TTTCCTGTTGGTGCTCACCCTCAACACCATGACCATTCTGCTGTCGGTGGCGGCGCTGGCGCTGGCGTGGGTCTACCCGT
TTATGAAGCGCTACACTCATCTGCCGCAGGTGGTGCTGGGCGCGGCCTTTGGCTGGTCGATCCCGATGGCCTTCTCGGCC
GTCAGCGAATCGCTGCCGCTGAGCTGCTGGCTGATGTTCCTCGCCAATATTCTGTGGGCGGTGGCCTACGATACCCAGTA
TGCGATGGTGGATCGCGATGACGACGTTAAGATCGGCATCAAGTCGACGGCGATCCTGTTTGGCGAAAACGATCGTCTGA
TTATCGGTATCCTGCAGGTGGCCGTACTGGCGCTGATGGGCGCGGTGGGTTGGCTGAATGGGCTGGGCTGGGAATATTAC
TGGTCGCTGTTCGTGGCGGCGGGTCTGTTTGGCTGGCAGCAGAAGCTTATCTTCAATCGCGACCGCGATAACTGCTTCAA
AGCGTTTATGAACAATAACTACGTCGGGCTGGTGCTGTTCCTCGGCCTGGCGATGAGCTACCTGTAA

Upstream 100 bases:

>100_bases
GCTGTGGGGGCGTCGTTCCCGCCTGCGGCTGAGCGGCAAACCCCTGCTGCTGACCGAGCTTTTTTTGCCTGCGTCGCCGT
TGTACTAAGAGGAAGAAAAA

Downstream 100 bases:

>100_bases
CCTCCTGTCCGCTGCCCCCCGGCATTCCGGGGGGCAGCAAACGCCGCGTTACGCGTCGTCCTGCGTGACGCTCTCAATGG
TCAGTCGGACATCCGACGTA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MEWSLSQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVASPGVPPLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TARRPLPSGDVTEKEARTLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFSA
VSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQVAVLALMGAVGWLNGLGWEYY
WSLFVAAGLFGWQQKLIFNRDRDNCFKAFMNNNYVGLVLFLGLAMSYL

Sequences:

>Translated_288_residues
MEWSLSQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVASPGVPPLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TARRPLPSGDVTEKEARTLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFSA
VSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQVAVLALMGAVGWLNGLGWEYY
WSLFVAAGLFGWQQKLIFNRDRDNCFKAFMNNNYVGLVLFLGLAMSYL
>Mature_288_residues
MEWSLSQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVASPGVPPLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TARRPLPSGDVTEKEARTLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFSA
VSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQVAVLALMGAVGWLNGLGWEYY
WSLFVAAGLFGWQQKLIFNRDRDNCFKAFMNNNYVGLVLFLGLAMSYL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=286, Percent_Identity=36.013986013986, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1790473, Length=287, Percent_Identity=89.198606271777, Blast_Score=501, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17553718, Length=286, Percent_Identity=37.0629370629371, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=37.0629370629371, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=30.1449275362319, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=144, Percent_Identity=43.75, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=43.3566433566434, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=31.5254237288136, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355567, Length=280, Percent_Identity=38.2142857142857, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32387; Mature: 32387

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSLSQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVASPGVPPLWILAVFVAGVWLMR
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTARRPLPSGDVTEKEARTLFIVLVLLSFLLVLTLNTMTIL
HCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFSAVSESLPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQVAVLALMGAVGWLNGLGWEYY
HHHCCEEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
WSLFVAAGLFGWQQKLIFNRDRDNCFKAFMNNNYVGLVLFLGLAMSYL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWSLSQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVASPGVPPLWILAVFVAGVWLMR
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTARRPLPSGDVTEKEARTLFIVLVLLSFLLVLTLNTMTIL
HCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFSAVSESLPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGENDRLIIGILQVAVLALMGAVGWLNGLGWEYY
HHHCCEEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
WSLFVAAGLFGWQQKLIFNRDRDNCFKAFMNNNYVGLVLFLGLAMSYL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA