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The map label for this gene is ubiC [H]

Identifier: 238892511

GI number: 238892511

Start: 295678

End: 296322

Strand: Direct

Name: ubiC [H]

Synonym: KP1_0279

Alternate gene names: 238892511

Gene position: 295678-296322 (Clockwise)

Preceding gene: 238892510

Following gene: 238892512

Centisome position: 5.63

GC content: 59.84

Gene sequence:

>645_bases
GTGCATCCTCCGGGATGCACCTTTTTTTGCACGCGCGGCAGCCTGTTGCATGGCTGTTGCGTGAATGATCGTATATTGAC
GTTTGCCCGCCACCAACCGCCTATTCTGCGATACAATGCTTTCACGTTATGTACCGGAGAATCAGGCATGTCCCATCCTG
CGCTTACGCGACTGCGTGCGCTGCGCTATTTTGCCGTTATGCCATCCCTGCCGCCGCCGCTAAGTGACTGGCTGCTGCTG
GAGGACTCAATGACCCAGCGCTTTGAACAACAAGGAAAGCAGGTCACCGTGACCCTGGTTAACGAAGGGTATATCGGCCG
TGACGCGCTGACTGACGAAGCGGCGCTGCTGCCCGACGAGCCGCGCTACTGGCTGCGGGAGATTATACTCAATGCCGATG
GCGAGCCCTGGCTGGCCGGGCGCACGGTGGCGCCGGAGTCGACGCTGTGTGGTCCGGAGCTGGCGCTACAGCAGCTCGGG
CAAACTCCGCTGGGCCGATACCTGTTTACGTCGTCGACATTAACCCGCGATTTTATTGAAATTGGTCGCGATGCAGCGCT
GTGGGGGCGTCGTTCCCGCCTGCGGCTGAGCGGCAAACCCCTGCTGCTGACCGAGCTTTTTTTGCCTGCGTCGCCGTTGT
ACTAA

Upstream 100 bases:

>100_bases
CGCCTCGGCTCGAAATCCGCTCGTTCCACCTTTATCAGCAGTGTAAAAGGCAAGGGGTAATCGTCTCCCCACAATGCTGA
TGTTTAGGCACAGCCTTTAG

Downstream 100 bases:

>100_bases
GAGGAAGAAAAAATGGAGTGGAGTCTGTCGCAGAATAAGCTGTTGGCGTTTCATCGCCTGATGCGCACTGACAAACCGAT
CGGCGCTTTGCTGCTGCTGT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHPPGCTFFCTRGSLLHGCCVNDRILTFARHQPPILRYNAFTLCTGESGMSHPALTRLRALRYFAVMPSLPPPLSDWLLL
EDSMTQRFEQQGKQVTVTLVNEGYIGRDALTDEAALLPDEPRYWLREIILNADGEPWLAGRTVAPESTLCGPELALQQLG
QTPLGRYLFTSSTLTRDFIEIGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY

Sequences:

>Translated_214_residues
MHPPGCTFFCTRGSLLHGCCVNDRILTFARHQPPILRYNAFTLCTGESGMSHPALTRLRALRYFAVMPSLPPPLSDWLLL
EDSMTQRFEQQGKQVTVTLVNEGYIGRDALTDEAALLPDEPRYWLREIILNADGEPWLAGRTVAPESTLCGPELALQQLG
QTPLGRYLFTSSTLTRDFIEIGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY
>Mature_214_residues
MHPPGCTFFCTRGSLLHGCCVNDRILTFARHQPPILRYNAFTLCTGESGMSHPALTRLRALRYFAVMPSLPPPLSDWLLL
EDSMTQRFEQQGKQVTVTLVNEGYIGRDALTDEAALLPDEPRYWLREIILNADGEPWLAGRTVAPESTLCGPELALQQLG
QTPLGRYLFTSSTLTRDFIEIGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=165, Percent_Identity=78.1818181818182, Blast_Score=258, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 24001; Mature: 24001

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPPGCTFFCTRGSLLHGCCVNDRILTFARHQPPILRYNAFTLCTGESGMSHPALTRLRA
CCCCCCEEEEECCCEEECEECCCCEEEEECCCCCEEEECEEEEEECCCCCCCHHHHHHHH
LRYFAVMPSLPPPLSDWLLLEDSMTQRFEQQGKQVTVTLVNEGYIGRDALTDEAALLPDE
HHHHHHCCCCCCCCCCEEEECHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
PRYWLREIILNADGEPWLAGRTVAPESTLCGPELALQQLGQTPLGRYLFTSSTLTRDFIE
HHHHHHHHHHCCCCCCEECCCEECCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHH
IGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY
HCCCHHHHCCCCEEEECCCCEEEEEHHCCCCCCC
>Mature Secondary Structure
MHPPGCTFFCTRGSLLHGCCVNDRILTFARHQPPILRYNAFTLCTGESGMSHPALTRLRA
CCCCCCEEEEECCCEEECEECCCCEEEEECCCCCEEEECEEEEEECCCCCCCHHHHHHHH
LRYFAVMPSLPPPLSDWLLLEDSMTQRFEQQGKQVTVTLVNEGYIGRDALTDEAALLPDE
HHHHHHCCCCCCCCCCEEEECHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
PRYWLREIILNADGEPWLAGRTVAPESTLCGPELALQQLGQTPLGRYLFTSSTLTRDFIE
HHHHHHHHHHCCCCCCEECCCEECCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHH
IGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY
HCCCHHHHCCCCEEEECCCCEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA